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Discover research articles across all indexed journals

Enhanced strength and chemical stability of Salix tetrasperma wood through thermal modification

Scientific Reports Sufiya Shabir, Bhupender Dutt, Rajneesh Kumar et al. Nov 27, 2025 DOI: 10.1038/s41598-025-27160-0

Integration of corpus linguistics and deep learning techniques for enhanced semantic-driven emotion detection on textual data

Scientific Reports Badriyya B. Al-onazi, Hassan Alshamrani, Hatim Dafaalla et al. Nov 27, 2025 DOI: 10.1038/s41598-025-28929-z

Evaluation of geological hazards susceptibility along a key railway based on machine learning

Scientific Reports Jiarong Liang, Wenwen Qi, Chong Xu et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26496-x

Influence of adjacent undercutting line positions on surrounding rock stability in block caving

Scientific Reports Yong Cao, Xinzhu Hua, Heng Zhang Nov 27, 2025 DOI: 10.1038/s41598-025-28625-y

Feasibility, accuracy and prognostic value of fully automated speckle tracking analysis-derived left ventricular ejection fraction and global longitudinal strain

Scientific Reports Yasufumi Nagata, Tetsuji Kitano, Yosuke Nabeshima et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26497-w

Abstract Left ventricular ejection fraction (LVEF) has been widely used for LV systolic assessment. However, it has drawbacks including large observer variability and unsatisfactory detectability of subclinical dysfunction. LV global longitudinal strain (LVGLS) by speckle-tracking on two-dimensional echocardiography (2DE) has been reported to be superior to LVEF. However, it may be influenced by the different methodology (manual versus semi-automated analyses) and biased study cohorts. A fully automated analysis can alleviate drawbacks of the LVEF and allow fair comparison between LVEF and LVGLS. We sought to evaluate the feasibility, accuracy of LVEF, and LVGLS measurements by the novel fully automated 2DE software against manual analysis and cardiac MRI feature-tracking (CMR-FT). Additionally, we tested prognostic utility of LVEF and LVGLS. In consecutive 436 patients undergoing CMR and 2DE, the fully automated analysis had excellent feasibility (97%). The correlation in LVEF and LVGLS between the fully automated analysis and the other two techniques was high ( r  = 0.82–0.95). During a median 26-month follow-up, 65 patients experienced cardiac events. In 422 patients successfully analyzed by the fully automated software (63 patients with cardiac events), both LVEF and LVGLS by the fully automated analysis were associated with cardiac events and their prognostic utility was not inferior to manual analyses. Nested Cox proportional hazard models and net reclassification analyses revealed fully automated analysis-derived LVEF and LVGLS did not have an incremental prognostic value over each other. A novel, fully automated analytical software demonstrated excellent applicability to clinical practice by providing reliable LVEF and LVGLS with comparable prognostic utility.

Macro- and meso- shear mechanical properties of rock-grout composite structures under different stress level and initial hydration damage

Scientific Reports Haoyu Rong, Guichen Li, Jiahui Xu et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26646-1

Abstract This study investigates the shear mechanical behavior of soft rock—grout coupled structures through triaxial shear tests and particle flow simulations on sandstone-resin composite specimens under varying normal stresses and immersion times. Key findings include: (1) Intensified hydration damage compromises shear resistance in both rock and interfaces, amplifies deformation, and degrades bearing capacity. (2) Elevated normal stress constrains microcrack coalescence, enhances bearing capacity. Failure modes of specimens—classified as interfacial shear sliding, mixed shear failure, or shear failure occurs exclusively within rock—depending on stress levels and hydration duration. (3) Prolonged immersion reduces energy thresholds for bond rupture, shifting crack propagation from abrupt surges to gradual increments. Weak zones migrate from interfaces to external rock. (4) Increased normal stress raises energy storage limits, suppresses microcrack coalescence, and strengthens weak zones. This study revealing the critical control of hydration damage and stress confinement on energy thresholds at the rock-grout interface, providing a theoretical basis for long-term stability prediction of anchorage structures.

Yielding brace system as a next-generation lateral load mechanism for seismic resilient cities

Scientific Reports Bush Rc, Varsha Rani, Anoop I. Shirkol et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26603-y

Higher-order sonification of the human brain

Scientific Reports Francisco-Shu Kitaura, Emi-Pauline Kitaura, Niels Janssen et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26438-7

Influence of layer thickness and extrusion ratio on strand morphology, porosity, surface roughness, and anisotropic mechanical properties in FDM

Scientific Reports Xiaofei Lou, Xin’an Tang, Lei Dong et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26253-0

Channel modeling and capacity optimization for optical RIS aided NOMA in indoor multiuser visible light communication IoT systems

Scientific Reports Mohamed El Jbari, Mohamed Moussaoui, Felipe Augusto Pereira de Figueiredo et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26674-x

Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

Nature Sanjeev S. Ranade, Feiya Li, Sean Whalen et al. Nov 27, 2025 DOI: 10.1038/s41586-025-09593-9

Strontium/copper doped nano-bioactive glass for biomedical applications

Scientific Reports Manar M. Ahmed, Amany A. El-Kheshen, Mona Moaness Nov 27, 2025 DOI: 10.1038/s41598-025-27551-3

Abstract This work is reported for the preparation and characterization of nano bioactive glass doped with copper and strontium in the system (SiO 2 -CaO-P 2 O 5 -CuO-SrO).Compared to traditional procedures, the Sol-gel approach offers a number of advantages for glass formation, including improved control over size and morphology. At the expense of CaO, CuO and SrO were added to the glass compositions. CuO and SrO were used for their highly antibacterial effects and bioactivity enhancement. To confirm the bioactivity of all the glass samples, scanning electron microscopy (SEM), Brunauer Emmett Teller (BET) surface area measurements, Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD) were used to assess the morphological and structural characteristics of the produced glasses. The particles that developed on the glass samples’ surface during immersion in the simulated body fluid (SBF) were analysed to detect the glasses’ bioactivity. The hydroxyapatite (HAp) layer’s development was verified by EDX analysis. ICP (Inductively Coupled Plasma) Spectroscopy was used to analyse the ion release in the SBF solution. Additionally, the impact of the antibacterial activity on several types of bacteria (including Gram-positive , Gram-negative , and antifungal bacteria ) was examined. Moreover, Ciprofloxacin was used as a model medication to test the drug loading efficiency. The Korsmeyer-Peppas kinetic model and zero order models were used to study the drug release mechanisms. The cytotoxicity of the nano-bioactive glass against human bone osteosarcoma cells (MG-63) and bone marrow stromal cells was also evaluated using the MTT assay.

Revisiting convolutional design for efficient CNN architectures in edge-aware applications

Scientific Reports Onur Erdem Korkmaz Nov 27, 2025 DOI: 10.1038/s41598-025-27856-3

Analysis of factors affecting the academic performance of university students using machine learning

Scientific Reports Yuri Reina Marín, Lenin Quiñones Huatangari, Judith Nathaly Alva Tuesta et al. Nov 27, 2025 DOI: 10.1038/s41598-025-28870-1

Investigating asphalt aggregate bonding degradation through aging and temperature effects using multiscale testing methods

Scientific Reports Lemin Liu, Tao Liu, Xiaohua Fan et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26507-x

Abstract Moisture damage in asphalt mixtures is a critical durability concern influenced by interfacial adhesion between asphalt and aggregates. This study systematically evaluates adhesion performance using digital image analysis and surface energy theory across four asphalt types (OR50, OR70, OR90, ORSBS) and five aggregates (limestone, basalt, granite, diabase, diorite). Key findings reveal that limestone exhibits superior adhesion stability (100% adhesion rate under aging) due to chemical bonding, while acidic aggregates (e.g., granite) show significant sensitivity to moisture and aging. A novel quantitative method combining water immersion tests and pixel-based stripping area analysis demonstrated high correlation (R 2 > 0.9) with surface energy-derived ER values, validating its reliability. Temperature and aging effects were further quantified, showing adhesion loss under thermal/oxidative aging, with SBS-modified asphalt outperforming base binders. These results provide a robust framework for material selection in pavement design, emphasizing aggregate alkalinity and polymer modification as key factors for moisture resistance.

The left ventricular mechanical dispersion as a marker of disease severity in transthyretin cardiac amyloidosis

Scientific Reports Katarzyna Holcman, Paweł Rubiś, Bogdan Ćmiel et al. Nov 27, 2025 DOI: 10.1038/s41598-025-26329-x

Integrating GAN-based machine learning with nonlinear Kalman filtering for enhanced state estimation

Scientific Reports Lior Tobaly, Eyal Yaniv, Zeev Zalevsky Nov 27, 2025 DOI: 10.1038/s41598-025-26339-9

Author Correction: Learning the natural history of human disease with generative transformers

Nature Artem Shmatko, Alexander Wolfgang Jung, Kumar Gaurav et al. Nov 27, 2025 DOI: 10.1038/s41586-025-09879-y

Bacteria use a decoy defence molecule to set a trap for viruses

Nature Malcolm F. White Nov 27, 2025 DOI: 10.1038/d41586-025-03125-1

Differential grain quality responses of rice varieties under combined salt, cadmium and arsenic stresses

Scientific Reports Sulthan Rifasa, Muhammed Ramzan Khan, Muhammed Uzair et al. Nov 27, 2025 DOI: 10.1038/s41598-025-29746-0