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Multicomponent Nanowire Aerogels With Tailored Adsorption Equilibrium for the Upcycling of Polyethylene Terephthalate
ABSTRACT Multicomponent nanowire aerogels (MNWAs) integrate 1D anisotropy with 3D porous frameworks, yet their synthesis remains challenging due to incompatible reduction kinetics and immiscibility of multicomponent systems. Herein, we develop a “confined topological transformation” strategy to directly fabricate MNWAs. We uncover the critical role of “confined interfacial bonding evolution competition mechanism” in governing noble metal interactions with Te templates during transformation. The MNWAs enable efficient value‐added conversion of polyethylene terephthalate (PET), demonstrating their practical potential. Specifically, the PdPtRuRhIrTe MNWAs/C exhibit remarkably high Faraday efficiency of 91.7% and yield rate of 12.05 mmol h −1 mg −1 for glycolic acid in electrocatalytic PET‐derived ethylene glycol oxidation reaction (EGOR), which is higher than that of multicomponent nanopartical aerogels and PdTe/PtTe/PdPtTe nanowire aerogels. Notably, the PdPtRuRhIrTe MNWAs/C maintain stable operation for over 1000 h in cyclic tests at an industrial‐level current density of 100 mA cm −2 in a membrane electrode assembly, with electrolyte replacement every 24 h. Further analysis and theoretical calculations reveal that the multicomponent nature synergistic effect of PdPtRuRhIrTe MNWAs promote the electronic and mass transmission, modulate the adsorption of surface‐adsorbed *OH and EG, thereby lowering the energy barrier of the potential determining step (the formation of *HOCH 2 CHOHOH) and ultimately enhancing the electrocatalytic performance.
Pathology‐Responsive Self‐Assembling Hydrogel Enabling Spatiotemporally Controlled Exosome Release and Redox Regulation for Intervertebral Disc Regeneration
ABSTRACT Intervertebral disc degeneration (IVDD) arises from disrupted metabolism and redox imbalance, severely impairing nucleus pulposus (NP) cells’ ability to repair the extracellular matrix (ECM). The early stage of IVDD is marked by excessive oxidative stress, lipid peroxidation, iron dysregulation and sustained catabolic enzyme activity, while late‐stage cellular aging ultimately renders NP cells highly susceptible to iron‐dependent cell death. To address these stage‐specific challenges, we developed a pathology‐adaptive self‐assembling hydrogel that exploits dynamically varying catabolic enzyme activity to trigger on‐demand delivery of antioxidant molecules and bioactive extracellular vesicles. Upon recognition of pathologically elevated MMP13, the hydrogel undergoes site‐specific structural disruption, thereby enabling spatiotemporally controlled exosome release. The hydrogel complex stabilizes redox balance by boosting intracellular glutathione, mitigating lipid peroxidation and restoring iron homeostasis. Furthermore, it activates PI3K‐Akt signaling and reinstates key anti‐ferroptosis proteins. Simultaneously, it promotes the synthesis of proteoglycans and type II collagen, collectively rebuilding the ECM niche. The combined effect of restored redox balance and regenerative signaling leads to significant structural and functional recovery of the damaged disc, as strongly evidenced in vivo animal studies. Overall, this spatiotemporal‐adaptive platform establishes a multifaceted strategy for regenerative engineering, offering a promising option for complex degenerative diseases.
Healable and Post‐Programmable Metal–Organic Framework—Vitrimer Composites
ABSTRACT Metal–organic framework (MOF) particles are commonly incorporated into polymer composites to impart porosity or functionality, but they often remain as fillers rather than defining the polymer network architecture. Here, we report a new design principle in which UiO‐66‐NH 2 nanoparticles are used as dynamic covalent crosslinkers for a linear polyimines to form MOF–vitrimer composites. Through imine bond formation between MOF‐bound amines and polymer aldehydes, the MOF becomes an integral network node, yielding free‐standing MOF–vitrimer composite films with high solvent resistance, while the MOF retains crystallinity. This architecture gives rise to properties beyond conventional MOF–polymer composites: dynamic imine exchange enables thermal healing, mechanical reprocessing, and chemical recycling. Furthermore, post‐synthetic tempering redistributes network connectivity and reprograms the mechanical properties from soft and extensible to stiff and strong, enabling material pluripotency and tunability to suit different applications. Unlike conventional organic crosslinkers, the MOF nodes also retain their intrinsic functions, allowing the composites to perform aqueous dye adsorption and organophosphate simulant hydrolysis while remaining easy to handle and recover. This work establishes MOFs as multifunctional dynamic crosslinkers for healable, recyclable, and post‐programmable hybrid materials, expanding MOF–polymer composites beyond passive filler architectures.
Solvation Reprogramming With Dual Cations Enables Catalytic Polysulfide Conversion and Stable Sodium Metal for Long‐Life Na‐S Batteries
ABSTRACT The practical development of room‐temperature sodium‐sulfur batteries faces significant challenges, primarily stemming from the polysulfide shuttle effect and the instability of the sodium anode. In this study, we propose a dual‐cation electrolyte engineering strategy that simultaneously addresses both bottlenecks by introducing K + into the conventional NaPF 6 /1‐ethoxy‐2‐(2‐methoxyethoxy)ethane electrolyte. The larger ionic radius and lower Lewis acidity of K + competitively modified the Na + solvation structure, weakening Na−Solvent interactions and reorganizing the solvation shell into contact ion pairs (CIPs), thus promoting the formation of inorganic‐rich solid electrolyte interphase. Theoretical calculations reveal that dominant NaKS x intermediates adsorbed via Na sites weaken S─S and Na─S bonds with dual‐cation induced charge delocalization, establishing catalytic cycle that lowers the kinetic barrier and relieves polysulfide shuttling. Meanwhile, the dendrite growth and parasitic side reactions are further suppressed within electrostatic shielding evoked by introduced K + . Consequently, a symmetric full cell architecture, with concave hollow mesoporous carbon nanospheres as both sulfur cathode matrix and sodiophilic anode coating, achieves a record lifespan of 10,000 cycles and a high‐capacity retention of 95.3% at 10 A g −1 and high energy density of 223 Wh kg −1 for pouch cell. This work offers a comprehensive design strategy, advancing practical metal‐sulfur batteries through electrolyte solvation and electrode interface engineering.
Suppressing Intrinsic Anti‐Site Defects via Targeted Li‐Occupation Unlocks Ultrahigh‐Rate Capability in Vanadium‐Free NASICON Cathodes
ABSTRACT Vanadium‐free Na superionic conductor (NASICON)‐type Na 3 MnTi(PO 4 ) 3 (NMTP) has been recognized as a prospective cathode material for sodium‐ion batteries owing to the abundance of raw materials, and its eco‐friendly composition. Yet the intrinsic anti‐site defects (IASDs) derived from the occupation of Mn 2+ on the Na‐vacancy site (Mn/M2_v) in NMTP severely deteriorates the Mn redox kinetics, causing abnormal voltage hysteresis and unsatisfactory rate performance. This study rationally designed a targeted Li‐occupation to effectively restrain the Mn/M2_v IASDs formation. Theoretical calculations identify that the tiny Li + ions preferentially occupy the alkali‐metal vacancies instead of Mn 2+ and selectively occupy M2 (18 e )‐sites rather than M1 (6 b )‐sites, thereby effectively inhibiting anti‐site occupation of Mn 2+ . This is experimentally validated in the prepared Na 2.95 Li 0.05 MnTi(PO 4 ) 3 (NMTP‐Li0.05), where minimal Li doping leads to significant suppression of Mn/M2_v IASDs. During charge‐discharge, the introduced Li + exhibits high mobility between M1/M2 sites and low electrostatic repulsion with Na + . Therefore, the NMTP‐Li0.05 achieves promoted kinetics with eliminated voltage hysteresis and an ultrahigh‐rate capability of 70.2 mA h g −1 at 100 C, which is exceptional among V‐free NASICON cathodes. This work establishes an effective strategy for IASDs suppression in polyanionic cathodes and paves the way for developing high‐performance and sustainable sodium‐ion batteries.
Strain‐Driven In Situ Ni Exsolution on (Sr,Ca)(Ti,Ni)O <sub>3</sub> (100) Facets Boosts Hydrogen Spillover and Selective CO <sub>2</sub> ‐to‐C <sub>2+</sub> Photoreduction
ABSTRACT Photocatalytic CO 2 reduction offers a sustainable route to value‐added chemicals, yet conventional systems suffer from limited efficiency and hydrocarbon selectivity due to the spatial mismatch between CO 2 adsorption and proton sources, delaying proton‐coupled electron transfer (PCET). Here, we construct a Ni/(Sr,Ca)(Ti,Ni)O 3 heterostructure (Ni/SCTNO) via molten salt exsolution and aluminothermic reduction. Ca 2+ doping introduces lattice strain, which drives the in situ exsolution of Ni nanoparticles on the (100) facet, while oxygen vacancies create a positive space charge layer. These effects synergistically form Schottky junctions that act as hydrogen spillover centers, enabling directional H* migration to CO 2 sites and spatiotemporally coordinating proton–electron transport. Under simulated sunlight, CH 4 , C 2 H 4 , and C 2 H 6 yields reach 41.89, 18.01, and 16.53 µmol·g − 1 ·h − 1 , respectively, with a total hydrocarbon selectivity of 55.03%, surpassing most reported perovskite‐based photocatalysts. This work presents an integrated strategy combining heterointerface engineering, strain regulation, and surface modification for efficient CO 2 ‐to‐multicarbon fuel conversion.
Circularly Polarized Lasing and Ultrafast Optical Helicity Switching in Chiral Perovskite Microcavities
ABSTRACT Robust helicity that can be generated intrinsically and controlled on ultrafast timescales would open attractive opportunities for terahertz photonic switching and chirality‐sensitive quantum devices. Yet such control remains challenging because the intrinsic chiral perturbation of molecular emitters is usually too small to establish a robust helicity bias that can break symmetry and sustain the ultrafast emergence and switching of a helicity‐selected optical state. In this study, we address this challenge by engineering chiral R/S quasi‐2D perovskite microcavities (R/S‐2DPMs) and establishing a hierarchical framework for chirality amplification in this platform. The resulting R/S 2DPMs support single‐mode lasing with quality factors on the order of 10 3 . Polarization‐resolved measurements show pronounced dissymmetry amplification from molecule dissymmetry of g mol ∼ 10 −4 to spontaneous emission dissymmetry of g sp ∼ 10 −2 and then through stimulated emission dissymmetry of g laser ∼ 0.78. Time‐resolved spectroscopy further reveals opposite ultrafast helicity switching on 1 ∼ 3 ps timescales in R/S‐enantiomeric microcavities. These results establish chiral quasi‐2D perovskite microcavities as a compact platform that converts weak microscopic chirality into robust circularly polarized lasing and ultrafast helicity switching, opening new opportunities for chiral photonics and helicity‐programmable coherent light sources.
Synergistic Design Strategies Breaking the Energy Storage Trade‐Off in Lead‐Free Dielectrics
ABSTRACT Development of lead‐free dielectric capacitors with simultaneously high recoverable energy‐storage (ES) density ( W rec ) and breakdown strength ( E b ) is hindered by a fundamental constraint; although high E b permits large electric fields, conventional ferroelectrics suffer from premature polarization saturation, limiting further enhancement of W rec . We demonstrate a mechanism‐guided strategy for Bi 0.5 Na 0.5 TiO 3 (BNT)‐based relaxor ferroelectric ceramics, centered on optimized polar nanoregion (PNR) responses and delayed polarization saturation. Phase‐field simulations show that interconnected rhombohedral/tetragonal (R/T)‐related PNRs with appropriate size and dynamic responsiveness can be progressively activated under electric fields, enabling delayed polarization saturation, sustained Δ P growth, and low hysteresis loss. Guided by this mechanism, compositional disorder, R/T phase coexistence are integrated in the BNT‐based system to construct an optimized PNR landscape. The optimized multilayer ceramic capacitors deliver a record ES potential ( ξ = W rec / E b ) of 278 J kV −1 m −2 , together with a high W rec of 26.4 J cm −3 at 950 kV cm −1 and 89% ES efficiency. Atomic‐resolution microscopy confirms pronounced local chemical heterogeneity and coexisting R/T‐related PNRs, consistent with the optimized PNR response predicted by phase‐field simulations. These results establish a generalizable framework for overcoming the intrinsic ξ – E b trade‐off and advancing next‐generation high‐ W rec dielectric capacitors for ES and pulsed‐power applications.
Anion‐Polarity‐Induced Interfacial Reconstruction Directs Crystallographic Texture for Highly Reversible Sn Anodes
ABSTRACT Controllable Sn electrodeposition is crucial for achieving highly reversible Sn metal batteries, but remains a significant challenge. Here, preferential exposure of Sn(211) planes with a uniform and compact morphology is achieved via an anion‐polarity‐driven interfacial regulation strategy during plating and stripping. Strong and crystallographically selective adsorption of CF 3 SO 3 − on Sn effectively modulates deposition behavior. Owing to its large intrinsic dipole, CF 3 SO 3 − establishes a pronounced surface‐normal interfacial dipole field on Sn(211), which suppresses growth along this plane while accelerating deposition on competing orientations, thereby driving the gradual evolution toward dominant Sn(211) exposure. Consequently, the reconstructed Sn anode delivers outstanding performance, including 99.88% Coulombic efficiency over 10,200 cycles at 10 mA cm −2 in Sn//Cu cells, ultralong cycling stability of 3456 h (∼4.8 months) in Sn//Sn symmetric cells, and 71% capacity retention after 20,000 cycles in full cells. The dipole‐based interfacial descriptor proposed in this work correlates anion polarity with crystallographic texture evolution in metal electrodeposition, providing a rational route toward controllable electrochemical reconstruction for high‐performance metal batteries.
Biointegrated Battery‐Based Electroceuticals
ABSTRACT Biointegrated batteries offer innovative technological platforms for tissue regeneration and disease treatment. Beyond serving as a power source for medical devices, they actively contribute to therapy by generating localized electric fields (EFs) and releasing therapeutically beneficial products. Accordingly, biointegrated batteries support a wide range of biomedical applications, including tissue regeneration, cancer therapy, cardiac pacing, and drug delivery. This review offers an overview of the recent advances in biointegrated battery‐based electroceuticals, emphasizing their applications in electrostimulation, electrochemical product‐mediated therapy, and drug delivery. This review provides a brief overview of the working principles of battery‐based electrocatalysts, focusing on their therapeutic mechanisms and highlighting their unique contributions in advancing disease treatment strategies. Finally, we discuss the future directions and provide insights into the broad adoption of battery‐based electroceutical technologies in next‐generation biomedical therapeutics.
Sub‐Nanometer Curvature Unlocks Quantum Orbital Flexoelectricity in Graphene
ABSTRACT Flexoelectricity, defined as polarization induced by strain gradients, is especially pronounced in two‐dimensional (2D) materials due to their mechanical flexibility and sensitivity to deformation. In nanostructures with nanometer‐scale curvature, bending can perturb out‐of‐plane π orbitals and generate quantum‐mechanical polarization and electrostatic modulation beyond classical lattice distortion alone. Here, we combine scanning probe measurements and first‐principles calculations to provide experimental and theoretical evidence for large intrinsic quantum orbital flexoelectricity in graphene nanowrinkles (GNWrs) with estimated polarization densities of P th ∼ 4 C m −2 and P exp ∼ 1 C m −2 , exceeding those of mesoscale systems by 5 to 7 orders of magnitude. These GNWrs exhibit high apex curvature, undergo atomic‐level buckling, and produce localized strain fields, as supported by atomic force microscopy analysis and Raman spectroscopy. Kelvin probe force microscopy reveals curvature‐dependent work‐function shifts, while conductive atomic force microscopy detects reproducible GNWr‐associated currents with a threshold voltage ( Φ th ∼ 1 V) comparable to the band offset predicted by ab initio calculations (∼ 1.2 V). These results support an interpretation in which curvature‐induced flexoelectric dipoles reshape the local electronic potential. GNWrs therefore provide a structurally simple carbon‐based platform for probing quantum‐mechanical flexoelectricity.
Universal Strategy for Phase‐Selective Synthesis of Monolayer TMDs via Colloidal Chemistry
ABSTRACT Colloidal synthesis of monolayer transition metal dichalcogenides (TMDs) remains challenging regarding uniform size, thickness, and crystalline phase. While significant progress has been made in phase engineering, a unified chemical strategy for on‐demand selection of both 2H and 1T′ phases across multiple TMD systems within a single chemical synthesis strategy has remained elusive. Here, we report a universal colloidal strategy for selective synthesis of both 2H and 1T′ phases across four representative TMDs — MoS 2 , MoSe 2 , WS 2 , and WSe 2 — by tuning the metal‐to‐chalcogen precursor ratio ([M]:[X]) and ligand composition. We demonstrate that phase selection in W‐based TMDs is governed primarily by precursor stoichiometry: relatively lower chalcogen ratios favor the metastable 1T′ phase, while higher ratios stabilize the thermodynamic 2H phase. In contrast, Mo‐based TMDs remain locked in the 2H phase regardless of precursor ratios; however, the introduction of oleic acid into an oleylamine‐based ligand environment induces successful synthesis of 1T′ phase. This work represents, for the first time, a general approach for phase‐selective synthesis of all four TMD analogues using common precursors and ligands. These results establish a generalized design principle for phase‐selective colloidal synthesis of TMDs and provide a foundation for exploring phase‐dependent quantum phenomena and functional properties.
Topological Crosslinker Design Regulates Interfacial and Active Species Transport in Zinc‐Iodine Batteries
ABSTRACT Aqueous zinc‐ion batteries (ZIBs) are limited by interfacial instability and an intrinsic trade‐off between mechanical strength and ionic conductivity in polymer gel electrolytes (PGEs), restricting their cycling durability and practical application. Here, we report a topology‐regulated crosslinker strategy that redefines crosslinkers from passive structural components to active regulators of ion transport and interfacial chemistry. A tetra‐armed poly(2‐ethyl‐2‐oxazoline) (4‐PEtOx) crosslinker is integrated into a zwitterionic network to construct a hydrogel electrolyte (4‐PVEX). The unique molecular topology establishes a dense yet dynamic hydrogen‐bonding framework, enabling continuous Zn 2+ transport pathways while maintaining high mechanical strength. As a result, 4‐PVEX stabilizes the Zn/electrolyte interface, promotes uniform dendrite‐free Zn deposition, suppresses parasitic reactions, and effectively immobilizes polyiodide species while accelerating iodine redox kinetics. Zn||Zn symmetric cell exhibits stable cycling for over 2700 h, and Zn||Cu cell delivers an average Coulombic efficiency of 99.7% over 1000 cycles. Moreover, Zn||I 2 full cell retains 90% of its initial capacity after 10 000 cycles at 10 C. This work demonstrates molecular topology as a powerful design dimension for advanced gel electrolytes and provides new insights into interfacial and transport regulation in aqueous metal batteries.
Activation‐Free Liquid‐Metal Composite Elastomers via Ultrasonic‐Enabled Interface Welding for Strain‐Insensitive Electronics
ABSTRACT Liquid metal (LM)‐based stretchable electronics are often limited by their native insulating oxide shell, typically necessitating destructive post‐activation or resulting in blends with limited extreme‐strain capabilities. Herein, we report an activation‐free LM composite elastomer (ALCE) featuring a robust metallurgical interface between LM nanoparticles and silver nanowires (Ag NWs). Unlike conventional physical mixing, we harness acoustic cavitation to facilitate in situ alloying. As the solvent subsequently evaporates, the welded components preferentially sediment to yield a macroscopic gradient architecture. This establishes a continuous conductive bottom network protected by a polymer‐rich upper layer, delivering a conductivity of 2.4 × 10 6 S/m. Benefiting from these robust welded junctions, the ALCE exhibits a distinctive initial decrease in resistance up to 400% strain, compensating for deformation‐induced resistance increases to achieve exceptional strain insensitivity ( R/R 0 = 1.8 at 1200% strain). Finally, we demonstrate its practical performance with robust stretchable sensors and a skin‐conformable human‐animal interactive system, establishing a scalable strategy toward high‐performance bioelectronics.
A Vertically Bandgap‐Cascaded Perovskite Single‐Crystal Film Heterojunction for On‐Chip Spectral Imaging
ABSTRACT On‐chip spectral imaging is highly attractive for portable sensing, precision inspection, biomedical analysis, and intelligent vision systems, yet it remains challenging to simultaneously achieve fast response and accurate spectral decoding within a compact device architecture. Here, we develop a vertically bandgap‐cascaded perovskite single‐crystal film heterojunction for computational spectral imaging. The monolithic MAPbCl 3 /MAPbBr 3 /MAPbI 3 single‐crystal film heterojunction (∼200 µm), fabricated by sequential solution epitaxy, integrates wavelength‐dependent absorption depth with staircase type‐I band alignment, enabling bias‐polarity‐switchable and depth‐selective carrier collection across the device thickness. This design produces electrically programmable spectral response codes while preserving high quantum efficiency and rapid photoresponse. The device exhibits a maximum external quantum efficiency (EQE) of ∼82%, a rise time as short as 8 µs, a peak‐wavelength accuracy of ∼1.4 nm, a spectral resolution of ∼2.7 nm, and broadband operation spanning ∼400–820 nm. Integration on a thin‐film transistor substrate further enables hyperspectral imaging and accurate spectral/color reconstruction, highlighting vertically engineered perovskite heterojunctions as a promising platform for compact, high‐performance spectral imaging.
De Novo‐Designed Peptide‐Engineered Multimodal Platform for Post‐Ischemic Stroke Tissue Repair
ABSTRACT Orchestrating tissue regeneration in complex pathologies like post‐ischemic stroke requires materials that can precisely regulate multiple signaling pathways. A central challenge is engineering a single platform integrating mechanical, electrical, and biochemical cues to redirect these pathological networks. Here, we present a computation‐driven, multimodal hydrogel engineered to function as a programmable regulatory node. The system integrates a computationally screened de novo vasculogenic peptide scaffold and surface‐engineered, inflammation‐responsive conductive MXene nanosheets. This rational surface engineering solves the critical bottleneck of MXene instability, preserving colloidal stability for over 2 months and maintaining high conductivity (1.2 mS/cm) within the injectable system. In a mouse model of ischemic stroke, this targeted modulation reconstructed the neurovascular unit integrity, suppressed glial scarring, and promoted remyelination and synaptic repair. Crucially, the platform re‐established neural electrical signal transmission, leading to the recovery of neural function. Mechanistically, machine learning‐driven transcriptomics highlighted Akt2 as a candidate regulatory hub, while untargeted metabolomics, prompted by a striking hair yellowing phenotype, suggested metabolic remodeling involving the phospholipase D signaling pathway. Our findings demonstrate a promising data‐driven, bottom‐up rational design paradigm for advanced bioelectronic tissue repair materials.
An Ultrathin, Permeable, and Battery‐Free Monolithically Integrated System for Emotion Sensing and Interaction
ABSTRACT Emotion regulation is critical for mental and physical health. Biomarkers such as dopamine and cortisol in body fluids are relevant to emotional status, while there is a lack of feasible devices to achieve personalized emotion management with minimized interferences. This study presents an ultrathin and battery‐free monolithically integrated sensing system for wireless tracking of stress‐related biomarkers with human–machine interaction. The system can be printed on a flexible and porous thermoplastic polyurethane (TPU) membrane with a thickness of around 36 µm, exhibiting remarkable air/moisture permeability of 162 mm/s and 1230 g/m 2 /day. It achieves dopamine and cortisol analysis with detection limits down to 0.25 µM and 1.65 nM. An integrated near‐field communication module enables wireless power harvesting and data transmission for continuous stress monitoring during daily activities, accompanied by emotion‐interactive feedback. The proposed printable method enables monolithic integration of multifunctional devices on ultrathin and permeable platforms toward mental health management in a wearable fashion.
Metal‐Organic Framework Electrolytes for Sub‐ –60°C Solid‐State Lithium Batteries
ABSTRACT Solid‐state lithium battery (SSLB) operating at ultralow temperatures (< −60°C) poses a formidable challenge for conventional solid‐state electrolytes (SSEs), including polymeric and inorganic materials. Herein, we report the design and fabrication of electron‐cloud‐homodistributed metal‐organic framework (ECH–MOF) with weakly temperature‐dependent Li + transport as SSE materials for SSLB operation at ultralow temperatures. To be specific, the metal nodes anchor electron‐rich ClO 4 − anions as Li + conducting sites, and organic ligands with strong electron‐withdrawing groups contribute to electron cloud homodistribution along Li + transport path, affording a spatially uniform, ultralow‐energy‐barrier landscape for ultralow‐temperature Li + transport. We reveal that Li + in ECH–MOF SSE migrates via a quantum‐tunneling‐like slipping manner, rather than the classical thermally activated hopping manner. The ECH‐MOF SSE yields the ultralow E a of 0.045 eV and single Li + conductivity of 1.2 × 10 −5 S cm −1 at −60°C—a temperature where most SSEs are essentially insulators. The assembled high‐voltage NCM 811||Li half‐cell delivers high discharge capacity of 109.2 mAh g −1 with high‐capacity retention of 62% after 1000 cycles at −60°C and 1C, extending the operational envelope of SSLBs into the ultralow‐temperature regime. The electron‐cloud homogenization strategy presents a universal platform for developing next‐generation low‐temperature ionic conductors (H + , Li + , Na + , Zn 2+ , etc.).
<i>Turritopsis nutricula</i> ‐Inspired Engineered Biomimetic Skin Promoting Aged Wound Repair via DAZAP1 Phase Separation‐Related Mitochondrial Metabolism Reprogramming
ABSTRACT Aging‐associated wound healing deficiency causes a variety of health complications and makes both economic and psychological burdens on patients greatly, with current therapies failing to address underlying pathophysiology and aging‐related impairments. Inspired by Turritopsis nutricula , we directly fabricated biomimetic skin matrix (BSM) from human adipose tissue (AT) by decellularization, then incorporated with amino‐functionalized apoptotic bodies (FABs) to construct a biomimetic skin (BSM@FABs). BSM@FABs effectively displayed high fibroblast affinity while reversing cellular senescence, accelerating migration, and stimulating neovascularization in aged wounds. Mechanistically, we identified a pioneering DAZAP1 liquid‐liquid phase separation (LLPS) triggered by BSM@FABs. These biomolecular condensates in the LLPS process enhanced tricarboxylic acid (TCA) cycle flux and oxidative phosphorylation (OXPHOS), concomitant with suppressed glycolysis and reduced mitochondrial reactive oxygen species, thereby resolving aging‐impaired mitochondrial dysfunction. Our work introduces a novel LLPS‐targeted strategy for aged wound treatment by reprogramming mitochondrial energy metabolism.
CVD Grown Hybrid MoSe <sub>2</sub> –WSe <sub>2</sub> Lateral/Vertical Heterostructures With Strong Interlayer Exciton Emission
ABSTRACT Lateral heterostructures (LHSs) of 2D transition metal dichalcogenides (TMDs) offer a powerful platform to investigate photonic and electronic phenomena at atomically sharp interfaces. However, their controlled engineering, including tuning lateral domain size and integration into vertical van der Waals heterostructures with other 2D materials, remains challenging. Here, we present a facile route for the synthesis of two types of heterostructures (HSs), consisting of monolayers (MLs) of MoSe 2 and WSe 2 —purely lateral (HS I) and hybrid lateral/vertical (HS II)—using liquid precursors of transition metal salts and chemical vapor deposition (CVD). Depending on the growth parameters, the heterostructure type and its lateral dimensions can be adjusted. We characterized properties of the HS I and HS II by complementary spectroscopic and microscopic techniques, including Raman and photoluminescence (PL) spectroscopy, optical and atomic force microscopy (AFM), and scanning and transmission electron microscopy (TEM). The PL measurements reveal strong interlayer exciton (IE) emission in the MoSe 2 /WSe 2 region of HS II, which dominates the spectrum at 4 K and persists up to room temperature (RT). These results demonstrate high optical quality of the grown HSs, which in combination with the scalability of the developed approach, pave the way for fundamental studies and device applications based on these unique 2D quantum materials.