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Uncovering novel photoluminescence characteristics of Cu2ZnSnS4 thin-film solar cells through pulsed laser excitation

Photoluminescence (PL) spectroscopy under pulsed laser excitation was employed to investigate the recombination mechanisms in a Cu2ZnSnS4 (CZTS) thin-film solar cell over a temperature range of 8–300 K. The PL spectra revealed one asymmetric band at 1.27 eV at T = 8 K, which was successfully fitted using an asymmetric double sigmoidal shape, indicating spatial variations in localized states and bandgap fluctuations. The PL band exhibited a temperature-dependent blue shift (∼0.26 meV/K) and low thermal activation energy (∼22 meV), suggesting recombination involving closely spaced deep donor–deep acceptor pairs. Laser power-dependent PL measurements at 8 K showed a pronounced blue shift of approximately 31 meV per decade of laser power, attributed to a band-filling effect under high excitation densities. The results support a model in which recombination occurs near band-bending regions. This study highlights the sensitivity of pulsed laser excitation PL, revealing previously unresolved recombination dynamics and localized states in CZTS-based photovoltaic materials.

Observation of single antiferromagnetic magnon modes through tunneling spectroscopy of spin-1/2 Kitaev system α-RuCl3

The small-gap room-temperature semiconductor α-RuCl3, which is known to undergo a Mott-Hubbard transition at low temperatures, is one of the most promising candidates for realization of an exotic matter form, the quantum spin liquid state, which may have applications in quantum computing. Although extensively investigated by neutron scattering techniques, electronic study of this system in the form of van der Waals heterostructures has been limited mainly to graphene proximity. Here, we report a systematic study of planar and tunneling electronic properties of α-RuCl3 films, where we observe an n-type field effect on α-RuCl3 films at room temperature, with a Mott insulator nature onset below 120 K. For films of three-layer thickness and below, we find inelastic scattering features below the Néel temperature of 7–14.5 K, which we attribute to single-magnon modes. Our study confirms preserved low-temperature signatures of the zigzag antiferromagnetic order in the atomically thin limit and its single-magnon modes within the continuum through tunneling spectroscopy.

Single-shot ultrafast dynamics of nanosecond pulsed plasmas: Transition from ps–ns nonequilibrium to near-full ionization

The ultrafast multi-stage evolution of state-defining properties in atmospheric-pressure nanosecond pulsed plasmas is quantified using single-discharge, jitter-free, continuous streak-sweep spectroscopy of N2(C → B) molecular and N+/O+ ionic species with a single-shot time resolution as short as ∼160 ps. An early period of extreme nonequilibrium is observed with vibrational temperatures [TV(C)] dropping from ∼8000 K at <200 ps after plasma breakdown to <4000 K within ∼1 ns, with near-ambient rotational temperatures [TR(C)] ∼ 300 K due to limited collisional energy transfer. This early-time TV(C) trend is representative of a direct and unquenched look into the high-energy tail of the electron energy distribution function; thus, it tracks real-time changes in the mean electron energy via the N2(C) emission signatures. This is followed by the rapid onset of N+/O+ ionic emission after a distinct time delay of ∼14.9 ns due to multistep chemical kinetics. The ionic emission enables determination of electron densities (ne) >2 × 1019 cm−3 and electron temperatures (Te) >36 000 K, indicating the transition to a nearly fully ionized regime. The ps–ns temporal dynamics are also compared between air and N2 plasmas to assess the influence of collisional partners, as well as across the anode, cathode, and central gap regions to identify spatial variations in plasma behavior. This work demonstrates versatile continuously probing approach capable of spectro-temporal and spatially resolved single-shot measurements of key state variables in the ps–ns evolution of atmospheric-pressure nanosecond pulsed plasmas.

The hepatic FGFR-ERK-HRG axis regulates heparin-induced thrombocytopenia with thrombosis

Heparin-induced thrombocytopenia (HIT) is a life-threatening prothrombotic disorder with substantial clinical mortality, characterized by pathologic antibody formation against platelet factor 4 (PF4)-heparin complexes. This study identified early pathologic mechanisms that initiate HIT immune complex formation and regulate thrombosis development. We found that repeated heparin administration over five days markedly enhanced platelet activation which implies an additional activating mechanism. Through plasma proteomic analysis, we observed that histidine-rich glycoprotein (HRG) levels were significantly reduced following successive heparin administration, and inversely related to platelet activation. Mechanistically, heparin and PF4 suppressed HRG expression via inhibiting the FGFR-ERK-Elk1 pathway whereby Elk1 directly binds to the HRG promoter region to regulate its liver expression. Physiological levels of HRG potently inhibited platelet activation, procoagulant activity, spreading, and aggregation, and significantly reduced thrombus formation under flow conditions. HRG bound to activated αIIbβ3 integrin in a zinc-dependent manner, thereby blocking its ligand-binding capacity. HRG also inhibited the formation of ultralarge PF4-heparin complexes (ULCs), disrupted the immune complexes (ULICs) comprising the HIT-like antibody KKO and ULCs, and blocked the binding of KKO to PF4/heparin on platelets. Furthermore, HRG attenuated ULCs-triggered autoantibody generation, inhibited the ULICs-induced neutrophil extracellular traps and microvascular thrombosis formation both in vitro and in a mouse model of HIT. In conclusion, our work establishes HRG as a pivotal regulator of pathologic immune responses and thrombosis in HIT, providing mechanistic insights into disease pathogenesis.

Publisher's Note: “Pressure-induced contact resistance dominance in scanning spreading resistance microscopy of undoped InAs/GaSb heterostructure” [Appl. Phys. Lett. <b>128</b> , 262106 (2026)]

HOW I TREAT BLEEDING IN WOMEN AND GIRLS WITH HEMOPHILIA/ HEMOPHILIA CARRIERS

Historically the impact of hemophilia for female carriers was believed to be restricted to their male offspring. Recent studies have highlighted the increased bleeding experienced by many hemophilia carriers, challenging traditional concepts of X-linked inheritance. These data have resulted in a mindset shift in the haemostasis community, culminating in the 2021 ISTH update on classification of hemophilia carriers. Women and girls with reduced factor VIII (FVIII) /factor IX (FIX) levels &amp;lt;0.40 IU/mL are now recognised as women and girls with hemophilia (WGH). Furthermore, hemophilia carriers who experience excessive bleeding despite normal FVIII/FIX levels are termed symptomatic carriers. Despite these changes, the impact of historic misconceptions surrounding hemophilia carriership remains and many families and healthcare providers may still believe that hemophilia carriers are at no risk of increased bleeding. Education is key to address these ongoing challenges and engagement with both hemophilia communities and physician organisations is critical. Hemophilia treatment centers must endeavour to ensure access for all hemophilia carriers and availability of services appropriate to needs of hemophilia carriers and WGH throughout their lifespan. In contrast to past publications that focus on pregnancy, in this article we address bleeding in hemophilia carriers and WGH at different life stages, including the impact of delay on diagnosis and the management of reproductive tract and joint bleeding.

Experimental observation of metamaterial-enabled high-density waveguides with low crosstalk

Crosstalk in densely spaced waveguides fundamentally constrains the integration density of photonic circuits. Although various strategies exist to mitigate crosstalk for transverse-electric (TE) modes, suppressing transverse-magnetic (TM) mode crosstalk remains challenging due to the weaker optical confinement of TM modes. Here, we address this challenge by introducing an anisotropic metamaterial between waveguide cores and the substrate, which effectively suppresses TM-mode crosstalk and enables dense waveguide integration. This mechanism is confirmed through both proof-of-principle microwave experiments and numerical simulations of on-chip silicon strip waveguides. We show that with a center-to-center separation of 1200 nm—nearly half the distance required by conventional waveguides—the designed silicon strip waveguides exhibit crosstalk below −20 dB for both fundamental TM and TE modes across a broad wavelength range from 1440 to 1555 nm. Our approach not only enhances the performance and integration compatibility of TM-mode-based photonic devices but also provides a viable pathway toward ultracompact, polarization-multiplexed integrated photonic circuits.

Measurable Residual Disease-Dependent Unfavorable Outcomes in Pediatric PAX5-Rearranged B-Acute Lymphoblastic Leukemia

PAX5-altered acute lymphoblastic leukemia (PAX5-alt ALL) is a recently recognized molecular subtype of B-ALL characterized by a distinct transcriptional signature and frequent PAX5 fusions (PAX5-r). While PAX5-alt ALL has been associated with intermediate outcomes, clinical data specifically investigating pediatric PAX5-r ALL remain limited. We collected and analyzed 159 pediatric cases of PAX5-r ALL treated between 2001-2024 within AIEOP-BFM ALL studies across Italy, Germany and Austria, revealing high-risk clinical features. Comparative analyses of patients consecutively enrolled in the AIEOP-BFM ALL 2017 study (PAX5-r, n=96 vs. non-PAX5-r, n=1948) confirmed higher rates of hyperleukocytosis at diagnosis (22.9% vs. 8%, p&amp;lt;0.001) and enrichment of IKZF1plus profile (14.7% vs. 7.8%, p=0.0015) in PAX5-r patients. No relevant differences in terms of minimal/measurable residual disease (MRD)-based treatment response and risk-group stratification were observed. PAX5-r patients had a 4-year EFS and OS of 72.6±5.7% and 95.4±2.3%, respectively. Four-year EFS were 100%, 63.4±9.7% and 63.3±10% for standard-risk, medium-risk (MR) and high-risk (HR) groups, respectively, indicating that the poor prognostic impact of PAX5-r applies only when end-of-induction MRD is positive (MR/HR). Whole transcriptome sequencing revealed high FLT3 median expression in PAX5-r ALL and high-throughput drug screening of patient-derived xenografts (PDXs) showed marked sensitivity to several FLT3 inhibitors. Gilteritinib showed potent ex vivo cytotoxicity and synergism with dexamethasone in PAX5-r PDX models. Collectively, this study investigated clinical and biological features of pediatric PAX5-r ALL highlighting its MRD-dependent unfavorable prognosis and identifying FLT3 overexpression as a novel, potential therapeutic target.

Splitting and merging behaviors of the positive streamer propagating in an atmospheric pressure argon plasma jet

Atmospheric pressure plasma jet (APPJ) offers extensive potential applications and has become a hot topic in low-temperature plasma research. The streamer dynamics are crucial to the distribution of reactive species in APPJ. To shed light on the streamer dynamics, the behaviors of splitting and merging are reported in this work for the positive streamer propagating in an argon APPJ. Results indicate that two discharges (the negative and the positive streamers) occur at the voltage rising edge and the falling edge, respectively. Their discharge intensities vary with changing pulse amplitude (Va) and bias voltage (Vb). High-speed photography reveals that the track of the positive streamer is filamentary, whose structure evolves with increasing Va from a cone, a fork, and to a fork and void. Additionally, the fork-and-void structure becomes a two-void shape with decreasing Vb. Moreover, the positive streamer demonstrates various behaviors, including linear propagation, splitting, merging, double splitting, and double merging. Spatial distributions of streamer velocity, electron excitation temperature, electron density, and molecular vibration temperature are also investigated. It is deduced that splitting and re-splitting are attributed separately to the negative ions and the Penning effect in the interfacial layer. If the negative ions in the interfacial layer are insufficient or the Penning effect at the axis is strong enough, merging and re-merging occur, respectively. The results mentioned above are of great significance for improving the performance of APPJ.

FERMT3 alternative splicing enhances kindlin-3 membrane recruitment for neutrophil adhesion during stress myelopoiesis

Leukocyte Adhesion Deficiency syndrome type III (LAD-III) is characterized by recurrent infections and is caused by FERMT3 gene mutations. FERMT3 encodes two isoforms, a standard kindlin-3 and a longer splicing variant, which differs by the addition of four residues Ile-Pro-Arg-Arg (IPRR) in the pleckstrin homology (PH) domain (kindlin-3-IPRR). Previous studies suggested that kindlin-3-IPRR was dysfunctional in inducing neutrophil adhesion, attributed to altered phospholipid binding of the IPRR-containing PH domain. Here we show that kindlin-3-IPRR is fully functional in activating β2 integrins and promotes neutrophil adhesion. The IPRR insert enhances phospholipid binding in vitro and promotes association of kindlin-3 with the plasma membrane. By analyzing RNA sequencing datasets of neutropoiesis, we show that the kindlin-3 short isoform lacking IPRR is highly expressed in neutrophil precursors but downregulated in mature neutrophils. In contrast, a higher proportion of the long isoform was detected in hematopoietic stem cells (HSCs) and mature neutrophils. Kindlin-3-IPRR supports robust adhesion of HSCs. We propose that kindlin-3-IPRR may be crucial in conditions requiring rapid neutrophil mobilization. Indeed, kindlin-3 splicing is altered in neutrophils from patients undergoing stress myelopoiesis after exposure to granulocyte colony-stimulating factor (G-CSF) or HSC transplantation (HSC-T) compared with healthy donors. During stress myelopoiesis induced by G-CSF treatment, the kindlin-3 long isoform is selectively upregulated in mature neutrophils, coinciding with enhanced β2 integrin activation. These findings support a model in which alternative splicing of FERMT3 dynamically fine-tunes integrin activation and leukocyte adhesion during hematopoietic stress, with potential implications for monitoring hematopoietic recovery after HSC transplantation.

Radiation force alignment for accurate orbital angular momentum measurement in acoustic vortex beams

We introduce a hologram-based method to determine the physically optimal axis for measuring the orbital angular momentum (OAM) transferred by acoustic vortex beams to an absorbing target. The axis is aligned with the net radiation force vector obtained from holographically measured pressure field. This alignment eliminates the transverse force component, making the measured torque independent of lateral position and equal to the OAM flux. The method is validated with vortex beams generated by multi-sector phase plates on a planar transducer and significantly improves upon conventional geometric alignment for nonparaxial and aberrated beams.

Risk of recurrence in patients with provoked venous thromboembolism: a prospective cohort study

Venous thromboembolism (VTE) provoked by transient risk factors is generally considered low risk, supporting short-term anticoagulation. However, this paradigm is based on heterogeneous definitions of provoking factors. In a prospective cohort study, we evaluated recurrence risk using the International Society on Thrombosis and Haemostasis (ISTH) classification of major and minor transient risk factors. Patients with symptomatic deep vein thrombosis and/or pulmonary embolism who completed ≥3 months of anticoagulation were followed after treatment discontinuation. Patients with cancer, major thrombophilia, pregnancy-associated VTE, or indication for extended anticoagulation were excluded. The primary outcome was symptomatic recurrent VTE. Cumulative incidence was estimated by Kaplan-Meier analysis. The study was terminated early due to unexpectedly high recurrence risk among patients with major provoking factors. Between 2019 and 2025, 242 patients were followed for a median of 23.9 months; 72 had major and 170 minor transient risk factors. Recurrent VTE occurred in 13 patients with major and 7 with minor risk factors. At 24 months, recurrence risk was 9.5% (95% CI, 6.0-14.0) overall, 19.7% (11.0-30.2) after major, and 5.0% (2.2-9.5) after minor risk factors. No recurrence occurred in 81 women with hormone-associated VTE; after their exclusion, the recurrence risk among patients with other minor risk factors increased to 9.1% (95% CI 4.0-17.0). Recurrence after provoked VTE is not uniformly low and varies substantially by the type of transient risk factor. These findings challenge current treatment paradigms and support individualized decisions regarding anticoagulation duration.

Surface-modified ZnO nanowire arrays ultraviolet photodetector with Cu nanoparticles for enhanced detection performance

The state-of-the-art ultraviolet photodetectors (UV PDs) have been extensively used in environmental monitoring, security checks, and optical communication. The conventional ZnO UV PDs often exhibit low sensitivity and slow response/decay speed. In this study, Cu nanoparticles (NPs) were first used to modify the surface of ZnO nanowire array (ZNWA) UV PDs. The results showed that after Cu NP modification, the dark current (Id) of the device at 5 V bias was reduced by more than one order of magnitude, while its responsivity and detectivity were about twice those of the ZNWA UV PD. The response and decay times reduced by 2.8 and 27.4 s, respectively. The present simple scheme offers a new strategy to suppress the Id in ZnO UV PDs for ultrasensitive photodetection applications.

Electrical-controlled and layer-filtered altermagnetic tunnel junction with all-in-one architecture

Altermagnets (AMs) offer a rare combination of zero net magnetization and non-relativistic spin splitting. However, achieving efficient switching of AM states remains a critical challenge for practical spintronic devices. Here, based on the finding that the external out-of-plane electric field lifts the band degeneracy of bilayer V2Se2O and hosts layer-dependent spin polarization at the Fermi level, we propose a scheme to achieve an all-electric-controlled AM tunnel junction solely with the bilayer V2Se2O via the first-principles quantum transport calculations. As the electric field applied to two ends switches from the same direction to the opposite direction, two prominent conduction states can be achieved, leading to a tunneling magnetoresistance as high as ∼1010%. Notably, the transport channels are layer-filtered, that is, only the bottom layer contributes to the tunneling unless the spin-splitting bands from the conduction and the valence bands cross together when the electric field increases to 0.25 V/Å. Our findings provide theoretical guidance for utilizing AM bilayers in low-power, high-speed memory devices and highlight a feasible route for the electrical manipulation of layer-resolved AM transport.

Sustainable Poly(Lactic Acid)/Graphene Oxide Bioelectronic Platform for Neurotransmitters Sensing and Tunable Stimulation of Astrocytes

ABSTRACT Biocompatible and biodegradable electrode platforms were developed using laser‐scribed poly(lactic acid)/graphene oxide (PLA/GO) composites, prepared via an innovative waterborne dispersion method. Laser treatment enabled the formation of graphene/graphite‐like structures. By varying the fluence of the laser used, it was possible to modulate the physico–chemical properties of the conductive traces obtained, finally leading to materials characterized by tunable sheet resistance, chemical structure, and morphology. Thanks to the low charge transfer resistance and the peculiar electrocatalytic and antifouling properties observed, the platforms were applied as electrochemical sensors for the detection of various biomarkers in biological fluids, namely ascorbic and uric acid, nicotinamide adenine dinucleotide (NADH) and catecholamine‐based neurotransmitters, outperforming commercial carbon screen‐printed electrodes. Contextually, laser‐scribed electrodes were used to demonstrate the effectiveness of a novel approach for selectively stimulating Ca 2 + signaling in astrocytes. The results here reported open the possibility to apply laser‐scribed PLA/GO as innovative eco‐sustainable solutions for simultaneous treatment of pathological conditions and monitoring of the resulting neurotransmitter expression in in vitro and in vivo models.

Dual Oxygen Precursors Boosting the Ionic Conductivity of Glassy Electrolytes for All‐Solid‐State Sodium Batteries

ABSTRACT Amorphous halide‐based solid electrolytes (SEs) are promising candidates for all‐solid‐state Na batteries (ASSNaBs) due to their structural flexibility and favorable mechanical properties. Among them, aluminum‐based halide electrolytes are particularly attractive owing to their low cost and oxidative stability; however, previously reported systems typically exhibit limited room‐temperature ionic conductivity (&lt;1 mS cm −1 ). In this work, we report the synthesis of a transparent, viscoelastic Na–Al SE with the specific composition 0.6NaClO–AlCl 3 –0.175SeO 2 , achieved through the strategic introduction of dual oxygen sources (NaClO and SeO 2 ). This approach enables the modulation of charge carrier concentrations while simultaneously supplying sufficient oxygen. Furthermore, we introduce the concept of deoxygenation enthalpy to rationalize the selection of these dual oxygen sources among various oxide candidates. The resulting electrolyte achieves a high Na + conductivity of 2.03 mS cm −1 at ambient temperatures, among the highest reported for Na–Al halide electrolytes. Molecular dynamics simulations confirm that segmental motion within the disordered framework actively facilitates Na + transport, underpinning the observed viscoelastic behavior. When integrated into ASSNaB with uncoated NaNi 0.4 Fe 0.2 Mn 0.4 O 2 cathode, the electrolyte enables stable long‐term cycling and superior thermal compatibility, demonstrating practical applicability. This work establishes a new paradigm in rational precursor design for high‐performance viscoelastic SEs.

Ultrafast Electrochromic Flexible Displays via Solvent‐Induced Porous and Loosely Packed Films

ABSTRACT Electrochromic devices (ECDs) represent one of the promising application areas of organic electrochromic materials, offering advantages such as low power consumption and nonemissive operation based on ambient light modulation. However, current electrochromic materials typically exhibit limited response speeds, which still pose a significant challenge to realizing truly dynamic display technology. In this work, we used tetrahydrofuran (THF) to induce solvation in a hydroxyl‐terminated side‐chain electrochromic polymer. The hydrogen bonds formed during this process generate induced polarization, which promotes the aligned arrangement of surrounding solvent molecules. Consequently, the uneven distribution of solvent triggers phase separation during spin‐coating, ultimately forming a porous electrochromic film with a high specific surface area. By constructing this multi‐layered porous thin film, we achieve a coloration response time of 0.87 s and a bleaching response time of 0.22 s, while maintaining a high optical contrast of 70.89% at 500 nm. Additionally, benefiting from the ability of hydrogen bonding to alleviate mechanical stress, we fabricated both active and passive display matrix prototypes on rigid and flexible substrates, achieving a fast switching rate of 0.1 s under a low operating voltage of 1.4 V (Bleaching time = 5 ms). This strategy exhibits a certain degree of generality, highlighting the potential of side‐chain‐engineered, solvent‐induced assembly for developing ultrafast electrochromic display materials.

Trions as Fundamental Species in Chemically Doped Polymer Semiconductors

ABSTRACT Doping is a cornerstone strategy for enhancing charge transport in semiconducting polymers, important for their application in, for example, semi‐transparent electrode materials, thermoelectric devices, and antistatic coatings. Both chemical and electrochemical doping have, for this purpose, been the focus of extensive research resulting in considerable progress. However, the interactions between neutral excitons and doping‐induced charges to form multi‐particle states are largely unexplored in soft organic semiconductors, and their signatures remain poorly understood. Here, we demonstrate that coupling between excitons and polarons in doped polymers can lead to bound states such as trions (i.e., quasiparticles of an electron and two holes delocalized across three chromophores for p ‐doping), or bound exciton‐hole pairs. Combining spectroscopic evidence with theoretical insights, we hypothesize that polymer architecture, dopant chemistry, and charge delocalization govern the formation and stability of these multi‐particle states. More broadly, our findings reveal that trions and bound exciton‐hole pairs—that is, three‐body entities—are a key species in organic semiconductors that could open new pathways toward optoelectronic functionalities beyond conventional doping, including enhanced charge transport and quantum‐coherent excitations.

Gold‐Stabilized Copper Enables Anodic Hydrogen Evolution for Ultralow‐Voltage CO‐to‐Ethylene Electrolysis

ABSTRACT Electrochemical upgrading from CO 2 and CO to ethylene has typically been coupled with the oxygen evolution reaction (OER), whose high standard reduction potential leads to full‐cell voltages above 2.2 V at 200 mA/cm 2 . Here we explored an alternative anodic reaction, where furfural is oxidized to furoic acid, a reaction having a low onset potential ( E 0 ≈ 0.05 V vs. RHE), and which reaction is accompanied by the evolution of H 2 : an anodic hydrogen evolution reaction (a‐HER). In early experiments, copper oxide as a‐HER catalyst exhibit limited stability (&lt; 10 min) and activity (80 mA/cm 2 at 0.8 V cell ). We found, using operando spectroscopy, that hydroxide forms on the surface of copper and deactivates the desired a‐HER process. When we screened candidate metal dopants, we found the best to be Au, for it served to stabilize the Cu surface, enablinained a‐HER: 260 mA cm −2 at 0.8 V cell and stable operation for 16 h. Integrated into a paired CO‐to‐ethylene electrolyzer, this delivered 0.92 V fullcell at 400 mA cm −2 , required 40 GJ electricity per ton of ethylene, and co‐produced 460 kg H 2 per ton ethylene. To enable comparison with CO 2 ‐to‐ethylene reports, which require an additional CO 2 ‐to‐CO step, we estimate ∼ 69 GJ/tonC 2 H 4 .

Bubble‐Assisted Dynamic Confinement Enables Programmable Solid‐State Photoswitching and Heterogeneous Photoresponsive Architectures

ABSTRACT Achieving programmable photoisomerization of azobenzenes in the solid‐state remains a long‐standing challenge for photoresponsive materials. Here, we introduce a dynamic soft‐confinement strategy using bubble‐assisted assembly to manipulate molecular aggregation via tunable surface energy at the solid‐liquid interface. By controlling the morphologies of microfluidic channels (necktie‐like, strip‐like, and necklace‐like), we achieve distinct self‐assembled aggregates of microcubes, corded scaffolds, and microplates, with tailored freedom of the photoswitchable molecule. The strip‐like channel, formed by thinning bubble walls, traps metastable intermediates, yielding a corded scaffold structure with favorable light penetration, weaker intermolecular interactions, and loosened molecular packing for isomerization. This design achieves near‐quantitative bidirectional E ⇆ Z photoisomerization (96%–98%) in the solid‐state, rivaling solution‐like performance. Multi‐scale characterization and computational analyses reveal the critical role of confined aggregation kinetics in controlling molecular motion. Furthermore, heterogeneous patterning demonstrates programmable photoresponsive arrays for photomechanical applications. This strategy provides a scalable platform for dynamically controlling supramolecular self‐assembly pathways and designing solid‐state photoresponsive materials with programmable functions.