Scientific Reports

Methylphenidate exposure alters brain gene expression and induces transgenerational DNA methylation changes in Poecilia reticulata guppies

Network analysis of serotonin CNVs shows biological convergence from genetic heterogeneity and discriminates between autism and developmental delay

Abstract Differentiating autism spectrum disorder (ASD) from developmental delay (DD) is critical for guiding early intervention, but overlapping features and shared biological mecha...

Tumor genome and microenvironment alteration by trastuzumab deruxtecan as neoadjuvant therapy for HER2-mutant NSCLC

H. pylori-induced hsa_circ_0085465 promotes gastric cancer cell proliferation, migration, and invasion by sponging miR-33b-3p

EEG-based biomarker for the identification of mild cognitive impairment via coherency analysis and iterative dynamic time warping

Herbosomal nanocarriers using natural-origin surfactants: a quercetin-based strategy for Alzheimer’s disease and oxidative-stress–driven neurodegeneration

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by oxidative stress, neuroinflammation, and cholinergic dysfunction. Quercetin (QUE) is a...

Detection of maxillary sinusitis of endodontic origin in cone-beam CT images using deep learning algorithms

Abstract Cone-Beam Computed Tomography (CBCT) scans were retrospectively collected and examined to acquire a balanced dataset representative of Normal Maxillary Sinus (NMS), Maxillar...

Household air pollution and under-five mortality in Kyrgyzstan: a survival analysis using multiple indicator cluster survey 2023 data

Novel rewiring mechanism for restoration of the fragmented social networks after attacks

Interpretable and extrapolation-stable model for predicting nanofluid thermal conductivity

Abstract Accurate prediction of nanofluid thermal conductivity is essential for the design of advanced thermal systems; however, existing approaches often face a...

First evidence of underground extractive tool use by chimpanzees in Kibale National Park, Uganda

Lightweight deep learning model for nonconvulsive status epilepticus diagnosis using EEG time–frequency analysis

Widely linear precoding with interference exploitation for improper signals in MU-MISO systems

A serious game for assessing upper-limb visuomotor adaptation in children with cerebral palsy during reaching tasks in virtual reality

Abstract Cerebral palsy (CP) is the most common non-progressive neurodevelopmental disorder, associated with impairments in motor control, posture, and adaptability. Understanding ho...

Development and external validation of a machine learning–based Cox model for predicting in-hospital survival in classic heatstroke: a multicenter retrospective study

Synthesis, in-vitro and in-silico bioactivity and computational studies of pyrene and p-methoxycinnamaldehyde linked 4-hydroxycoumarins

Reference-guided genome assembly of long non-coding rna transcripts reveals target genes associated with Crohn’s disease

Dynamic teaching path generation for quadruped robot programming by integrating R-GCN and SBERT

Simultaneous removal of fluoride and arsenic from water in a fixed-bed column using Fe-Al-MOF/CF composite: optimization by response surface methodology

Development and validation of the student readiness and anxiety scale for AI-assisted biology teaching (SRAS-AIBT)

Outdoor high-precision 3D dense mapping system based on stereo visual SLAM

Cervical microbial dysbiosis in single HPV16-positive HSIL

Development of a model for design radiation shielding composite aprons using machine learning

A multi-domain graph-integrated neural framework for robust acoustic anomaly detection under adverse environmental conditions

Abstract Acoustic event understanding and anomaly detection play a critical role in security monitoring, defence applications, and urban safety, yet current appr...

Sutureless capsular bag–intraocular lens complex scleral fixation using iris retractors in eyes with crystalline lens subluxation: long-term outcome