Nature Communications
Articles in this Issue
Pantothenate kinase 4 controls skeletal muscle substrate metabolism
AbstractMetabolic flexibility in skeletal muscle is essential for maintaining healthy glucose and lipid metabolism, and its dysfunction is closely linked to metabolic diseases. Exercise enhances metab...
Virtual Frisch grid perovskite CsPbBr3 semiconductor with 2.2-centimeter thickness for high energy resolution gamma-ray spectrometer
Maximizing the clinical utility and performance of cytology samples for comprehensive genetic profiling
Abstract Comprehensive molecular profiling by next-generation sequencing has revolutionized tumor classification and biomarker evaluation. However, routine imple...
Fam102a translocates Runx2 and Rbpjl to facilitate Osterix expression and bone formation
AbstractBone remodeling maintains the robustness of the bone tissue by balancing bone resorption by osteoclasts and bone formation by osteoblasts. Although these cells together play a crucial role in...
Enterocyte-like differentiation defines metabolic gene signatures of CMS3 colorectal cancers and provides therapeutic vulnerability
Evidence for saddle point-driven charge density wave on the surface of heavily hole-doped iron arsenide superconductors
AbstractUnconventional superconductivity is known for its intertwining with other correlated states, making exploration of the intertwined orders important for understanding its pairing mechanism. In...
Nucleus-translocated GCLM promotes chemoresistance in colorectal cancer through a moonlighting function
AbstractMetabolic enzymes perform moonlighting functions during tumor progression, including the modulation of chemoresistance. However, the underlying mechanisms of these functions remain elusive. He...
Characterization and structural analysis of a versatile aromatic prenyltransferase for imidazole-containing diketopiperazines
Glia detect and transiently protect against dendrite substructure disruption in C. elegans
Compound electron acceleration at planetary foreshocks
AbstractShock waves, the interface of supersonic and subsonic plasma flows, are the primary region for charged particle acceleration in multiple space plasma systems, including Earth’s bow shock, whic...
Sulfur-locked multiple resonance emitters for high performance orange-red/deep-red OLEDs
All-solid-state batteries designed for operation under extreme cold conditions
A soft thermal sensor for the continuous assessment of flow in vascular access
AbstractHemodialysis for chronic kidney disease (CKD) relies on vascular access (VA) devices, such as arteriovenous fistulas (AVF), grafts (AVG), or catheters, to maintain blood flow. Nonetheless, unp...
NHSL3 controls single and collective cell migration through two distinct mechanisms
AbstractThe molecular mechanisms underlying cell migration remain incompletely understood. Here, we show that knock-out cells for NHSL3, the most recently identified member of the Nance-Horan Syndrome...
Room-temperature creation and conversion of individual skyrmion bags in magnetic multilayered disks
Soft Metalens for Broadband Ultrasonic Focusing through Aberration Layers
Paracrine role of endothelial IGF-1 receptor in depot-specific adipose tissue adaptation in male mice
AbstractDuring recent decades, changes in lifestyle have led to widespread nutritional obesity and its related complications. Remodelling adipose tissue as a therapeutic goal for obesity and its compl...
Gigantic Tellegen responses in metamaterials
Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
Distinct roles of dentate gyrus and medial entorhinal cortex inputs for phase precession and temporal correlations in the hippocampal CA3 area
AbstractThe hippocampal CA3 subregion is a densely connected recurrent circuit that supports memory by generating and storing sequential neuronal activity patterns that reflect recent experience. Whil...
DPFunc: accurately predicting protein function via deep learning with domain-guided structure information
Dengue virus IgG and neutralizing antibody titers measured with standard and mature viruses are protective
A new class of natural anthelmintics targeting lipid metabolism
Structures of Saccharolobus solfataricus initiation complexes with leaderless mRNAs highlight archaeal features and eukaryotic proximity
AbstractThe archaeal ribosome is of the eukaryotic type. TACK and Asgard superphyla, the closest relatives of eukaryotes, have ribosomes containing eukaryotic ribosomal proteins not found in other arc...
Targeting pleuro-alveolar junctions reverses lung fibrosis in mice
Abstract Lung fibrosis development utilizes alveolar macrophages, with mechanisms that are incompletely understood. Here, we fate map connective tissue during mouse lung fibrosis and observe...