Nature Communications

Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism

Wataru Shihoya, Hiroaki Akasaka, Peter A. Jordan et al. Apr 22, 2025 10.1038/s41467-025-57960-x

Apolipoprotein-A1 transports and regulates MMP2 in the blood

Hassan Sarker, Rashmi Panigrahi, Ana Lopez-Campistrous et al. Apr 22, 2025 10.1038/s41467-025-59062-0

Detecting and calibrating large biases in global onshore wind power assessment across temporal scales

Chengzhi Hou, Zhiwei Xu, Kristopher B. Karnauskas et al. Apr 22, 2025 10.1038/s41467-025-59195-2

Atomically precise Ni clusters inducing active NiN2 sites with uniform-large vacancies towards efficient CO2-to-CO conversion

Guangyuan Xu, Xingjie Peng, Chuanqiang Wu et al. Apr 22, 2025 10.1038/s41467-025-59079-5

Structural basis of human Mediator recruitment by the phosphorylated transcription factor Elk-1

Didier Monté, Zoé Lens, Frédérique Dewitte et al. Apr 22, 2025 10.1038/s41467-025-59014-8

Abstract One function of Mediator complex subunit MED23 is to mediate transcriptional activation by the phosphorylated transcription factor Elk-1, in response to the Ras-MAPK signaling pathw...

The mammalian longevity associated acetylome

S. Feldman-Trabelsi, N. Touitou, R. Nagar et al. Apr 22, 2025 10.1038/s41467-025-58762-x

Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN

David Herreros, Carlos Perez Mata, Chari Noddings et al. Apr 22, 2025 10.1038/s41467-025-59135-0

Abstract Single-particle analysis by Cryo-electron microscopy (CryoEM) provides direct access to the conformations of macromolecules. Traditional methods assume discrete conformation...

Self-adaptive and large-area sprayable thermal management coatings for energy saving

Peng Zhou, Guangyang Jiang, Yuyan Wang et al. Apr 22, 2025 10.1038/s41467-025-59259-3

Shape morphing of soft robotics by pneumatic torsion strip braiding

Changchun Wu, Hao Liu, Senyuan Lin et al. Apr 22, 2025 10.1038/s41467-025-59051-3

Proton-coupled electron transfer controls peroxide activation initiated by a solid-water interface

Jian-Hua Chen, Wan-Ting Li, Kun-Yu Cai et al. Apr 22, 2025 10.1038/s41467-025-58917-w

Chloroplast precursor protein preClpD overaccumulation triggers multilevel reprogramming of gene expression and a heat shock-like response

Zheng-Hui Hong, Liyu Zhu, Lin-Lin Gao et al. Apr 22, 2025 10.1038/s41467-025-59043-3

Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria

Elisabetta Cacace, Manuela Tietgen, Meike Steinhauer et al. Apr 22, 2025 10.1038/s41467-025-58730-5

Abstract Nitroxoline is a bacteriostatic quinoline antibiotic, known to form complexes with metals. Its clinical indications are limited to uncomplicated urinary...

Targeted immunotherapy rescues pulmonary fibrosis by reducing activated fibroblasts and regulating alveolar cell profile

Jing Yan, Song-Yu Wang, Qi Su et al. Apr 21, 2025 10.1038/s41467-025-59093-7

Metal-organic double layer to stabilize selective multi-carbon electrosynthesis

Jian Cheng, Ling Chen, Yanzhi Zhang et al. Apr 21, 2025 10.1038/s41467-025-59025-5

High-temperature ferrimagnetic order triggered metal-to-insulator transition in CaCu3Ni2Os2O12

Xubin Ye, Yunyu Yin, Yingying Cao et al. Apr 21, 2025 10.1038/s41467-025-59041-5

Deconvolution of cell types and states in spatial multiomics utilizing TACIT

Khoa L. A. Huynh, Katarzyna M. Tyc, Bruno F. Matuck et al. Apr 21, 2025 10.1038/s41467-025-58874-4

Electron transfer engineering of artificially designed cell factory for complete biosynthesis of steroids

Qihang Chen, Wenqian Wei, Zikai Chao et al. Apr 21, 2025 10.1038/s41467-025-58926-9

Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing

Wiep van der Toorn, Patrick Bohn, Wang Liu-Wei et al. Apr 21, 2025 10.1038/s41467-025-59102-9

Abstract Nanopore direct RNA sequencing (dRNA-seq) enables unique insights into RNA biology. However, applications are currently limited by the lack of accurate and cost-effective sa...

Stereopy: modeling comparative and spatiotemporal cellular heterogeneity via multi-sample spatial transcriptomics

Shuangsang Fang, Mengyang Xu, Lei Cao et al. Apr 21, 2025 10.1038/s41467-025-58079-9

Evidence for excitonic condensation and superfluidity in black phosphorus

Jiadong Mei, Yue Wang, Ruixiang Fei et al. Apr 21, 2025 10.1038/s41467-025-58886-0

Unlocking the phase evolution of the hidden non-polar to ferroelectric transition in HfO2-based bulk crystals

Shuxian Wang, Yihao Shen, Xiaoyu Yang et al. Apr 21, 2025 10.1038/s41467-025-59018-4

Fe(OTf)3 or Photosensitizer-free blue light activated diazo-thioglycoside donors for Iterative and stereoselective glycosylations

Surya Pratap Singh, Umesh Chaudhary, Adrienne Daróczi et al. Apr 21, 2025 10.1038/s41467-025-56445-1

Age-related divergence of circulating immune responses in patients with solid tumors treated with immune checkpoint inhibitors

Chester Kao, Soren Charmsaz, Hua-Ling Tsai et al. Apr 21, 2025 10.1038/s41467-025-58512-z

Abstract Most new cancer diagnoses occur in patients over the age of 65. The composition and function of the immune system changes with age, but how the aged immune system affects responses...

Targeting CD38 immunometabolic checkpoint improves metabolic fitness and cognition in a mouse model of Alzheimer’s disease

Javier María Peralta Ramos, Giulia Castellani, Denise Kviatcovsky et al. Apr 20, 2025 10.1038/s41467-025-58494-y

The nucleoid of rapidly growing Escherichia coli localizes close to the inner membrane and is organized by transcription, translation, and cell geometry

Christoph Spahn, Stuart Middlemiss, Estibaliz Gómez-de-Mariscal et al. Apr 20, 2025 10.1038/s41467-025-58723-4

Abstract Bacterial chromosomes are spatiotemporally organized and sensitive to environmental changes. However, the mechanisms underlying chromosome configuration and reorganization a...

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