Nature Communications
Articles in this Issue
Equity and reliability of public electric vehicle charging stations in the United States
Abstract Equitable coverage and reliable operation of electric vehicle charging stations (EVCSs) are crucial for a just transition to a carbon-free future. Yet, a comprehensive national anal...
Author Correction: Focal liver lesion diagnosis with deep learning and multistage CT imaging
Reversible proliferative arrest induced by rapid depletion of RNase MRP
Abstract Cellular quiescence is a state of reversible proliferative arrest that plays essential roles in development, resistance to stress, aging, and longevity of organisms. Here we report...
USP37 prevents premature disassembly of stressed replisomes by TRAIP
Abstract The eukaryotic replisome, which consists of the CDC45-MCM2-7-GINS (CMG) helicase, replicative polymerases, and several accessory factors, sometimes enco...
Cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens
Enzymatic twists evolved stereo-divergent alkaloids in the Solanaceae family
Switch-like gene expression modulates disease risk
The green algae CO2 concentrating mechanism and photorespiration jointly operate during acclimation to low CO2
Abstract Due to low availability of CO2 in aquatic environment, microalgae have evolved a CO2 concentrating mechanism (CCM). It has long been thought that operation of CCM would suppress pho...
Unveiling hidden particle-level defects in glasses
Single-cell analysis reveals immune cell abnormalities underlying the clinical heterogeneity of patients with systemic sclerosis
Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis
Abstract Anti-NMDA receptor (NMDAR) encephalitis is a devastating disease with severe psychiatric and neurological symptoms believed to be caused by pathogenic autoantibodies that bind to th...
Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62
Abstract Aneuploidy, or aberrant chromosomal content, disrupts cellular proteostasis through altered expression of numerous proteins. Aneuploid cells accumulate SQSTM1/p62-positive c...
Stable heritability of type 1 diabetes in a Swedish Nationwide Cohort Study
Abstract Incidence of type 1 diabetes is increasing globally, which is hypothesized to be due to environmental influences. We leverage Swedish nationwide registers linked to all children (n ...
A continental scale analysis reveals widespread root bimodality
Author Correction: Characteristics of the first confirmed case of human infection with mpox virus clade Ib in China
Bladder cancer variants share aggressive features including a CA125+ cell state and targetable TM4SF1 expression
Abstract Histologic variant (HV) subtypes of bladder cancer are clinically aggressive tumors that are more resistant to standard therapy compared to conventional urothelial carcinoma (UC). L...
TRPML2 in distinct states reveals the activation and modulation principles of the TRPML family
Spectral properties of two superconducting artificial atoms coupled to a resonator in the ultrastrong coupling regime
Circulating cell-free DNA methylation patterns indicate cellular sources of allograft injury after liver transplant
Abstract Post-transplant complications reduce allograft and recipient survival. Current approaches for detecting allograft injury non-invasively are limited and do not differentiate...
Nuclear deformability increases PARPi sensitivity in BRCA1-deficient cells by increasing microtubule-dependent DNA break mobility
Abstract Microtubules and nuclear transmembrane SUN1/2 proteins promote the mobility of DNA Double Strand Breaks (DSBs) induced by ionizing radiation and the misrepair of one-ended DSBs indu...
Publisher Correction: A machine learning and centrifugal microfluidics platform for bedside prediction of sepsis
stClinic dissects clinically relevant niches by integrating spatial multi-slice multi-omics data in dynamic graphs
Abstract Spatial multi-slice multi-omics (SMSMO) integration has transformed our understanding of cellular niches, particularly in tumors. However, challenges like data scale and diversity,...
Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas
Abstract A major challenge hampering therapeutic advancements for high-risk sarcoma patients is the broad spectrum of molecularly distinct sarcoma types and the corresponding lack of suitabl...
Global warming may increase the burden of obstructive sleep apnea
Abstract High ambient temperatures are associated with reduced sleep duration and quality, but effects on obstructive sleep apnea (OSA) severity are unknown. Here we quantify the effect of 2...