Nature Communications
Articles in this Issue
Metabolomics and proteomics reveal blocking argininosuccinate synthetase 1 alleviates colitis in mice
Efficient GHz electro-optical modulation with a nonlocal lithium niobate metasurface in the linear and nonlinear regime
Abstract Electro-optical modulation is essential in optical signal processing and laser technology, yet modulators based on the Pockels effect in flat optics lag behind bulk and integrated p...
Microscopic theory of polariton group velocity renormalization
Isotope-driven hydrogel smart windows for self-adaptive thermoregulation
The structure of the Tad pilus alignment complex reveals a periplasmic conduit for pilus extension
Abstract The Tad ( T ight ad herence) pilus is a bacterial appendage implicated i...
Single urinary extracellular vesicle proteomics identifies complement receptor CD35 as a biomarker for sepsis-associated acute kidney injury
Exploring the intersection of natural sciences and information technology via entropy and randomness
Tunable reciprocal and nonreciprocal contributions to 1D Coulomb drag
Vinyl cyclopropanes as a unifying platform for enantioselective remote difunctionalization of alkenes
Abstract Asymmetric remote difunctionalization of alkenes is a longstanding challenge in synthetic chemistry, offering the potential to install two functional groups simultaneously across di...
Time-dependent catalytic activity in aging condensates
Abstract Biomolecular condensates are dynamic cellular compartments that concentrate proteins and enzymes to regulate biochemical reactions in time and space. While these condensates can enh...
Simulations and active learning enable efficient identification of an experimentally-validated broad coronavirus inhibitor
Abstract Drug screening resembles finding a needle in a haystack: identifying a few effective inhibitors from a large pool of potential drugs. Large experimental screens are expensive and ti...
Epigenomic diagnosis and prognosis of Acute Myeloid Leukemia
Abstract Despite the critical role of DNA methylation, clinical implementations harnessing its promise have not been described in acute myeloid leukemia. Utilizing DNA methylation fr...
An on-chip phased array for non-classical light
Abstract Quantum science and technology can offer fundamental enhancements in sensing, communications and computing. The expansion from wired to wireless links is an exciting prospect for qu...
Cas13d-mediated isoform-specific RNA knockdown with a unified computational and experimental toolbox
Single-nuclei multiomics analysis identifies abnormal cardiomyocytes in a murine model of cardiac development
Heterogeneous preferences and asymmetric insights for AI use among welfare claimants and non-claimants
Abstract The deployment of AI in welfare benefit allocation accelerates decision-making but has led to unfair denials and false fraud accusations. In the US and UK (N = 3249), we examine pub...
2-oxoglutarate:acceptor oxidoreductase-catalyzed redox cycling effectively targets coccoid forms of Helicobacter pylori
A single mutation may contribute to accelerated evolution of SARS-CoV-2 toward Omicron
Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers
Abstract ADAR1 is an RNA editing enzyme which prevents autoimmunity by blocking interferon responses triggered by cytosolic RNA sensors, and is a potential target in immuno-oncology. However...
Bridging small molecule calculations and predictable polymer mechanical properties
Multichannel bioelectronic sensing using engineered Escherichia coli
Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis
Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes
Abstract Wolbachia is a promising strategy to inhibit dengue virus (DENV) transmission by Ae. aegypti...