Nature Communications
Articles in this Issue
Chemically modified tRNA enhances the translation capacity of mRNA rich in cognate codons
Noncanonical terpene cyclases for the biosynthesis of diterpenoids regulating chlamydospore formation in plant-associated Trichoderma
The Escherichia coli replication initiator DnaA is titrated on the chromosome
Abstract DNA replication initiation is orchestrated in bacteria by the replication initiator DnaA. Two models for regulation of DnaA activity in...
LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation
Néel spin-orbit torque in antiferromagnetic quantum spin and anomalous Hall insulators
Abstract Interplay between topological electrons and magnetic ordering enables efficient electrical control of magnetism. We extend the Kane-Mele model to include the exchange coupling to a...
STN1 facilitates metastasis by promoting transcription of EMT-activator ZEB1 in pancreatic cancer
Promiscuous and multivalent interactions between Eps15 and partner protein Dab2 generate a complex interaction network
Abstract Clathrin-mediated endocytosis depends on complex protein interactions. Eps15 plays a key role through interactions of its three EH domains with Asn-Pro-...
Root-to-shoot mobile mRNA CmoKARI1 promotes JA-Ile biosynthesis to confer chilling tolerance in grafted cucumbers
Flavonoid pathway intermediates implicate UVR8 in functions beyond canonical UV-B signaling
A small set of critical hyper-motifs governs heterogeneous flow-weighted network resilience
Visualization of enantiorecognition by excited-state conformation modulation
Metagenomic analysis reveals how multiple stressors disrupt virus–host interactions in multi-trophic freshwater mesocosms
Decoding technical multi-promoted ammonia synthesis catalysts
Abstract Ammonia is industrially produced by the Haber-Bosch process over a fused, multi-promoted iron-based catalyst. Current knowledge about the reaction has been derived from model system...
Structures and mechanisms of U6 snRNA m6A modification by METTL16
The bispecific innate cell engager AFM28 eliminates CD123+ leukemic stem and progenitor cells in AML and MDS
Abstract Strategies targeting leukemic stem and progenitor cells (LSPCs) are needed for durable remissions in acute myeloid leukemia (AML) and high-risk myelodysplastic neoplasms (MDS). Whil...
Highly scalable prefusion-stabilized RSV F vaccine with enhanced immunogenicity and robust protection
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma
Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women
Abstract Breast cancer (BC) is one of the most common cancers globally. Genetic testing facilitates screening and informs targeted risk-reduction and treatments. However, genes included in t...
Internally hollow Cu2O nanoframes with the abundance of {110} facets enhance direct propylene epoxidation
Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus
CO-promoted polyethylene hydrogenolysis with renewable formic acid as hydrogen donor
Integrating artificial intelligence and optogenetics for Parkinson’s disease diagnosis and therapeutics in male mice
Abstract Parkinson’s disease (PD), a progressive neurodegenerative disorder, presents complex motor symptoms and lacks effective disease-modifying treatments. Here we show that integrating a...
Catalytic cooperation between Ru and Pd atoms on hierarchical porous Ce-based oxide for boosting engine exhaust purification
Global warming reduces the carrying capacity of the tallest angiosperm species (Eucalyptus regnans)
Abstract Rising temperatures and increased frequency and intensity of droughts and heat waves have affected tree mortality rates worldwide. Here, we investigate how these changes have affect...