Nature Communications
Articles in this Issue
GLUT6-facilitated noncanonical glucose metabolic rewiring enables resistance to targeted cancer therapy
Host oxidative stress primes mycobacteria for rapid antibiotic resistance evolution
Abstract The rapid emergence of multidrug-resistant Mycobacterium tuberculosis (Mtb) threatens global tuberculosis (TB) c...
Deep-learning-empowered programmable topolectrical circuits
Satellite quantification of enhanced methane oxidation applied to the stratospheric plume following Hunga Tonga-Hunga Ha’apai eruption
Abstract Methane is a powerful greenhouse gas whose atmospheric sink remains uncertain, and emerging strategies to enhance its removal will require quantification and monitoring to v...
Evidence of hydrological regime shifts associated with a major decades-long drought in West Africa
The entorhinal spatial map integrates visual identity information of landmarks
Abstract Landmarks guide navigation by providing information through their location and identity. The medial entorhinal cortex (MEC) is well known for representing landmark location,...
Pivoting forestry and agricultural concessions toward conservation in Southeast Asia
Ferroptosis-armed dendritic cell vaccines for glioma immunotherapy
Abstract The type of cell death has proven to play a crucial role in cancer immunotherapy efficacy. Immunogenic cell death (ICD) enhances tumor adjuvanticity and antigenicity by rele...
Risk-adapted therapy guided by human papillomavirus (HPV) circulating tumor DNA in HPV-positive oropharyngeal cancer (ReACT 1.0): an exploratory phase II trial
CCDC120 phase separation contributes to desmosomal integrity and cardiac function
ANXA11 suppression restores muscular function in the mdx mouse model of Duchenne muscular dystrophy (DMD)
Channelized topography amplifies melt-sensitivity of cold Antarctic ice shelves
Abstract The stability of Antarctic ice shelves, which regulate the flow of grounded ice into the ocean, depends critically on ocean-driven basal melting. Basal channels, widespread...
MOF gel network crosslinked mixed matrix membranes with engineered interface for high-efficiency Helium recovery
Signal peptide peptidase-like proteases OsSPPL1 and OsSPPL2 facilitate ER-associated protein degradation in rice
Ultrahigh efficiency solar evaporation through orchestrated multiphase flow
Cellular and molecular basis of PfCoronin function in artemisinin resistance in Plasmodium falciparum
SCOTCH: isoform-level characterization of gene expression through long-read single-cell RNA sequencing
EV-ready building codes and electric vehicle adoption
A DeepSeek-powered AI system for automated chest radiograph interpretation in clinical practice
Abstract A global shortage of radiologists has increased the burden of chest X-ray interpretation, particularly in primary and resource-limited settings. Although artificial intellig...
Single-site oxidation-directed topological evolution of hydrogen-bonded organic frameworks for efficient photocatalysis
Mitochondria serve as a holdout compartment for aggregation-prone proteins hindering efficient degradation
Abstract The accumulation of protein aggregates has been causatively linked to the pathogenesis of neurodegenerative diseases. Here, we conduct a genome-wide CRISPR-Cas9 screen to id...
Trees halve urban heat island effect globally but unequal benefits only modestly mitigate climate-change warming
Photorealistic 3D Holographic Display with Natural Defocus Effect
Dynamic strength of iron under pressure-temperature conditions of Earth’s inner core
Predicting trajectories of illness using RNA velocity of whole blood
Abstract Transcriptomic analyses reveal the status of cells, tissues, or organisms, across states of health and disease. RNA velocity adds a temporal dimension to single cell analyse...