Nature Communications
Articles in this Issue
Vibration-assisted fabrication of thin shells with spatially distributed imperfections
Abstract Thin-shell structures, found in biological systems such as beetle carapaces and widely used in aerospace and civil engineering, achieve remarkable strength-to-mass ratios gi...
Evolutionary diversity of cell-type-specific expression and stress response in Brassicaceae roots
Click-like Aldol Polycondensation in air for plastic electronics and beyond
Pan-genome analysis uncovers extensive structural variations in Africa’s indigenous legume crop cowpea
Polyadenylation of insulin mRNA by Tent5a regulates pancreatic beta cells
Abstract Pancreatic beta cells can compensate for increased metabolic demand by increasing their function. While many studies have investigated mechanisms of beta cell decompensation...
Evidence for Eocene aridification of the Atacama Desert’s hyperarid core
Abstract The Atacama Desert is the most arid non-polar region on Earth, yet the timing and drivers of its hyperaridity remain debated. The earliest record of ext...
Physics-informed multi-encoder adaptive optics enables rapid aberration correction for intravital microscopy of deep complex tissue
Multi-modal AI for comprehensive breast cancer prognostication
Precise discrimination of G-quadruplex conformation by chiral nanoassembly with photo-reversibility
High-depth whole genome sequencing of premalignant breast lesions reveals rearrangement hotspots and personalized management opportunities
Abstract Ductal carcinoma in situ is a non-obligate precursor lesion of breast cancer. Often detected by mammography, most cases are managed through surgical and/or radiotherapy appr...
An epifluorescence microscope design for naturalistic behavior and cellular activity in freely moving Caenorhabditis elegans
Abstract Understanding the neural basis of behavior requires imaging cellular activity in freely moving animals, which typically demands expensive, restrictive m...
Integrated genomic analyses identify oncogenic pathway interplay in hepatocarcinogenesis defining specific molecular subtypes
Kynurenic acid mediates epicardial fat-induced lymphatic metabolic dysfunction in atrial fibrillation
Abstract Atrial fibrillation represents a prevalent cardiac arrhythmia whose pathogenic mechanisms remain incompletely understood. Here, we identify impaired atrial lymphangiogenesis...
A modular multi-color fluorescence microscope for simultaneous tracking of cellular activity and behavior
Abstract We present a modular epifluorescence tracking microscope which enables ratiometric imaging of muscles, neurons, and other structures in moving animals....
An attention-demanding hunting paradigm engages the superior colliculus–zona incerta circuit mediating analgesia in male mice
Joint clinical and molecular subtyping of COPD with variational autoencoders
Spring–Summer Caribbean Sea marine heatwaves tied to previous Winter Indian Ocean marine heatwaves
Dual site targeting of the bacterial 70S ribosome by tetracyclines
Stem cell activity is linked to a transient acquisition of pluripotency during callus proliferation
Substrate recognition and allosteric inhibition of human betaine/GABA transporter 1
Recurrent evolution of ligand-binding domain multiplicity fine-tunes TGFβ signaling in vertebrates
Abstract From sponges to mammals, TGFβ signalling is a central regulator of body plan, cell fate and tissue homeostasis, with receptor architecture highly conserved across metazoans....
Genetic determinants of Staphylococcus aureus adhesion shape virulence trade-offs in bacteremia
Local drivers in accelerating North American heat stress
Abstract Climate change increases heat extremes, threatening human health and economies. Using reanalysis data and climate simulations, we show that since the 1940s, population expos...
Compounding hazards increase flood economic losses across Europe
Abstract Compound events-combinations of multiple hazards contributing to societal or environmental risk-can significantly exacerbate disaster impacts, yet their effect on flood-rela...