Nature Communications
Articles in this Issue
Recurrent connections facilitate occluded object recognition by explaining-away
Abstract Despite the ubiquity of recurrent connections in the brain, their role in visual processing is less understood than that of feedforward connections. Occluded object recognit...
Plasma proteome mediates the associations between air pollution exposure and disease risk
Ultra-coherent meta-emitter tailors arbitrary thermal wavefront
Discover the maze-like network for glabridin biosynthesis
Ultralow CNT-reinforced phase-change fibers for scalable wearable thermoregulation
Probing the molecular structure at graphite–water interfaces by correlating 3D-AFM and SHINERS
Abstract Water at solid surfaces is key for many processes ranging from biological signal transduction to membrane separation and renewable energy conversion. However, under realisti...
Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C
Safety and biologic activity of a bispecific T cell receptor targeting HIV Gag in males living with HIV: a first-in-human trial
Abstract HIV persistence in reservoirs despite antiretroviral therapy (ART) is a barrier to a permanent cure. We present the affinity-enhanced TCR bispecific IMC...
Molecular signatures of resilience to Alzheimer’s disease in neocortical layer 4 neurons
Abstract Selective neuronal vulnerability is a hallmark of Alzheimer’s disease (AD), yet the molecular basis of resilience remains poorly understood. Using singl...
A spatiotemporal atlas of cerebrovascular development in zebrafish
Fluorescence mapping of atropisomer populations enabled by through-space conjugation
Reliable repurposing of the antibody interactome inside the cell
Abstract Eighty-five percent of the human proteome has at least one interacting monoclonal antibody. These molecules penetrate the cytoplasm poorly and are very often non-functional...
Neoadjuvant modified FOLFIRINOX plus nivolumab in borderline-resectable pancreatic ductal adenocarcinoma: a pilot phase 1 trial
Abstract Chemotherapy and immune checkpoint inhibitor combinations have failed to improve survival in pancreatic ductal adenocarcinoma (PDAC), except in rare microsatellite instabili...
Tomato antiviral ubiquitin-proteasome system recognizes viral 59 kDa protein to confer tomato chlorosis virus resistance
Nanotwin architecture and ultra-high valley degeneracy lead to high thermoelectric performance in GeTe-based thermoelectric materials
Abstract Here, we achieve a high peak ZT of 2.5 as well as an exceptional average ZT...
Enhanced methane chlorination via RuO2-gas convection electrode with in-situ generated dynamical three-phase boundaries
Architectural and evolutionary features of TE-derived TSSs shape tissue-specific promoter activity in the human genome
Abstract Transposable elements are abundant in the human genome and have been increasingly recognized as sources of alternative promoters. Yet, the extent of their transcriptional ac...
Early detection of aberrant cell fate and repair using circulating progenitor cells in patients with heterotopic ossification
Multicomponent synergistic immobilization via in-situ and dynamic exchange strategies for constructing hierarchical biopharmaceuticals
Room-temperature polariton condensate in a quasi-2D hybrid perovskite
Abstract Quasi-2D halide perovskites are chemically synthesized realizations of quantum well stacks with giant exciton oscillator strengths, tunable emission spe...
Printed origami thermoelectric generator achieves > 20 Wm−² from low-grade heat via material and process design
Abstract Printing facilitates low-cost thermoelectric generators to power battery-free internet-of-things devices, wearables, and Industry 4.0 systems. However,...
Transition to bio-based plastic packaging reveals complex climate–biodiversity trade-offs
Abstract Plastics are a major contributor to global greenhouse gas emissions and biodiversity loss, with packaging accounting for around 40% of European plastic production. Bio-based...
DNA diamond formulates a decomposable composite letter constellation model for DNA data storage
Abstract Oligonucleotide multiplicity is an inherent property of current DNA synthesis technology. Composite letter DNA storage exploits this property to improve logical density and...
Covalent modification of a glutamic acid inspired by HaloTag technology
Abstract For targeted covalent protein modification at low-reactivity aspartates and glutamates, new methods are in high demand. We report a technique inspired by the HaloTag technol...