Nature Communications
Articles in this Issue
Conformational biosensors delineate endosomal G protein regulation by GPCRs
Abstract Many GPCRs trigger a second phase of G protein-coupled signaling from endosomes after signaling from the plasma membrane, necessitating GPCRs to increas...
H pilin cyclisation and pilus biogenesis are promiscuous but electrostatic perturbations impair conjugation efficiency
Abstract During conjugation, plasmid DNA is transferred from donor to recipient bacteria via the plasmid-encoded mating pilus, formed as thin helical assemblies of polymerised pilin...
Isolable radical cation and dication of dialumene
Abstract Alkenes are known to undergo successive oxidation to form alkene-derived radical cations and dications, which have found applications across various fields. As the aluminum...
Cooperative clamp-mediated promoter recognition by poxviral RNA polymerase and its TBP/TFIIB-like partner
Abstract The recruitment of RNA polymerase to gene promoters is a critical step in gene expression. For RNA polymerase II, this process is initiated by TBP and TFIIB, with homologs o...
Phase diagram and spectroscopic signatures of a supersolid in the quantum ising magnet K2Co(SeO3)2
Interface-driven energy-independent charge extraction in GaN photocatalysts
Abstract Ultrafast charge transfer dynamics are key to photocatalytic efficiency, governing energy relaxation and surface reactivity. However, the temporal evolution of carrier energ...
Turbulent dynamo in the terrestrial magnetosheath
cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis
Energy-sensing molecule RORγ regulates cholesterol metabolism and immune signaling in diabetic kidney disease and aging
Structural defects in amyloid-β fibrils drive secondary nucleation
Abstract Formation of new amyloid fibrils and oligomers from monomeric protein on the surfaces of existing fibrils is an important driver of many disorders such as Alzheimer’s and Pa...
Eelgrass ecosystem collapse and social-ecological regime shift driven by hydropower development and climate change
Mitochondrial heteroplasmy is a risk factor for the development of chronic lymphocytic leukemia
A bacterial YopJ-family acetyltransferase suppresses host immune response by Nε-acetylation of JAK1
R-loop editing by DNA cytosine deaminase APOBEC3B modulates the activity of oestrogen receptor enhancers
Abstract Oestrogen receptor (ER) activation leads to the formation of DNA double strand breaks (DSB), promoting genomic instability and tumour heterogeneity. The single-stranded DNA...
Non-cascade random walks in solid-state high harmonic generation
Abstract Random walks—both classical and quantum—unlocked new possibilities in search algorithms and information processing. Although linear photonic systems, with flexible tunabilit...
A Stellar magnesium to silicon ratio in the atmosphere of an exoplanet
Abstract The elemental compositions of exoplanets encode information about their formation environments and internal structures. While volatile ratios such as ca...
Hidden pressure-stabilized lead reservoirs in Earth’s mantle
Ocean dynamics shape marine heatwaves and their predictability
Abstract Marine heatwaves have become more frequent and intense under anthropogenic warming, posing increasing threats to marine ecosystems and coastal societies, necessitating a bet...
Thermal catalytic synthesis of ammonia using uranium/graphdiyne composite at mild conditions
ATPγS substantially defeats the biasing mechanism for kinesin steps
Abstract Kinesin-1 microtubule motors are ATP-fuelled, twin-headed cargo transporters that step processively along microtubules, with a load-dependent directional bias. Here we show...
Quantum coupling in colloidal homodimers of epitaxially attached CdSe@CdS dot@platelets probed on single-particle level
An aqueous battery using an electrolyte with a pH of 7 and suitable for direct environmental discard
Structural insight into hierarchical DNMT3A autoinhibition and its dysregulation in disease
Abstract DNA methyltransferase DNMT3A-mediated DNA methylation is important for genomic imprinting and transcriptional regulation. However, how the regulatory domains of DNMT3A coope...