cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis

Hideo Negishi; Yusuke Wada; Yoshitaka Shirasaki; Tomoya Hayashi; Yuji Kubota; Tomio Iwasaki; Mina Kurosawa; Tatsuma Ban; Daisuke Muto; Yusuke Suenaga; Taichi Kojima; Yuzuki Matsuda; Sean Lord Irish; Kosuke Dodo; Toru Suzuki; Mai Yamagishi; Burcu Temizoz; Atsushi Yoshimori; Chisato Kanai; Yoji Nagasaki; Masaki Ohmuraya; Tomohiko Tamura; Atsushi Iwama; Toshifumi Inada; Etsushi Kuroda; Kouji Kobiyama; Noriko Toyama-Sorimachi; Mutsuhiro Takekawa; Cevayir Coban; Ken J. Ishii

doi:10.1038/s41467-026-68839-w

cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis

H Hideo Negishi Y Yusuke Wada Y Yoshitaka Shirasaki T Tomoya Hayashi Y Yuji Kubota T Tomio Iwasaki M Mina Kurosawa T Tatsuma Ban D Daisuke Muto Y Yusuke Suenaga T Taichi Kojima Y Yuzuki Matsuda S Sean Lord Irish K Kosuke Dodo T Toru Suzuki M Mai Yamagishi B Burcu Temizoz A Atsushi Yoshimori C Chisato Kanai Y Yoji Nagasaki M Masaki Ohmuraya T Tomohiko Tamura A Atsushi Iwama T Toshifumi Inada E Etsushi Kuroda K Kouji Kobiyama N Noriko Toyama-Sorimachi M Mutsuhiro Takekawa C Cevayir Coban K Ken J. Ishii (Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health and Nutrition, Saito Asagi)

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published February 18, 2026

DOI 10.1038/s41467-026-68839-w

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (30)

H

Hideo Negishi

Y

Yusuke Wada

Y

Yoshitaka Shirasaki

T

Tomoya Hayashi

Y

Yuji Kubota

T

Tomio Iwasaki

M

Mina Kurosawa

T

Tatsuma Ban

D

Daisuke Muto

Y

Yusuke Suenaga

T

Taichi Kojima

Y

Yuzuki Matsuda

S

Sean Lord Irish

K

Kosuke Dodo

T

Toru Suzuki

M

Mai Yamagishi

B

Burcu Temizoz

A

Atsushi Yoshimori

C

Chisato Kanai

Y

Yoji Nagasaki

M

Masaki Ohmuraya

T

Tomohiko Tamura

A

Atsushi Iwama

T

Toshifumi Inada

E

Etsushi Kuroda

K

Kouji Kobiyama

N

Noriko Toyama-Sorimachi

M

Mutsuhiro Takekawa

C

Cevayir Coban

K

Ken J. Ishii

Laboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant Research, National Institutes of Biomedical Innovation, Health and Nutrition, Saito Asagi

cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis

Article Details

Journal Info

Authors (30)

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