Nature Communications
Articles in this Issue
Selective control of prefrontal neural timescales by parietal cortex
Abstract The frontal eye field (FEF) and posterior parietal cortex (PPC) are key hubs of the dorsal attention network, yet how parietal inputs shape prefrontal circuit temporal dynam...
Purkinje cell intrinsic activity shapes cerebellar development and function
Abstract The emergence of functional cerebellar circuits is heavily influenced by activity-dependent processes. However, the contribution of intrinsic Purkinje c...
Nitrogen fixation in a non-equilibrium spatially distributed electric field
Gene expression dynamics of human and mouse craniofacial development at the single-cell level
Cerebrospinal fluid NPTX1 and NPTXR predict neurodegeneration and clinical progression in Alzheimer’s disease
Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage
Abstract Neural crest cells contribute to craniofacial formation by differentiating into skeletogenic mesenchyme and neuro-glial lineages. Using Smart-seq2 singl...
Getting robots back on track by reconstituting control in unexpected situations with online learning
Abstract Robotic systems are increasingly common in strictly controlled environments (e.g. warehouses), but they have yet to fully integrate into our everyday lives. Everyday scenari...
Long-read sequencing of families reveals increased germline and postzygotic mutation rates in repetitive DNA
Abstract Long-read sequencing improves sensitivity to discover variation in complex repetitive regions, assign parent-of-origin, and distinguish germline from po...
DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsis
Distinct genomic trajectory among invasive Salmonella Typhimurium ST313 infections
Bioengineered ferritin-based lysosome-targeting chimera platform for tumor-targeted therapy
Amphotericin B promotes respiratory viral entry by enhancing late endosomal maturation and fusion via glucocerebrosidase-mediated ceramide remodeling
Abstract Respiratory viral infections, such as influenza and COVID-19, pose significant global health challenges. For patients with invasive pulmonary aspergillo...
Perovskite solar cells with enhanced thermal fatigue resistance under extreme temperature cycling
Abstract Metal halide perovskite solar cells combine high power density with low-cost manufacturing, but durability under repeated extreme temperature cycling remains insufficiently...
Restoration of RBM22 overcomes the transcriptional and epigenetic barriers of cardiomyocyte proliferation for heart regeneration
p38 MAPK orchestrates cross-tissue potassium homeostasis for survival
Modulation of Pt electron transfer via engineered ultra-thin TiO2-Al2O3 interfaces for coke-resistant methane dry reforming
CryoEM structure of mGlu6 captures receptor activation prior to G protein coupling
Single-cell genomics highlight MYC-associated metabolic activation and altered cell interactions in T-prolymphocytic leukemia progression
Abstract T-prolymphocytic leukemia (T-PLL) typically presents with rapidly progressing tumor burden. However, 15–25% of cases are diagnosed at an indolent stage with asymptomatic and...
CXCR4-tropic HIV-1 infection in an immunocompetent monkey model
NPM3 functions as a lactyltransferase to promote necroptosis in male diabetic cardiomyopathy mice models via FASN transcription modulation
Water mass specific genes dominate the Southern Ocean microbiome
Abstract The Southern Ocean (SO) plays a key role in regulating global biogeochemical cycles and climate, yet microbial genes sustaining its biological activity remain poorly charact...
Epilepsy-associated FOXJ3 variants link a transcriptional program of the PTEN-mTOR pathway to neuronal specification and cortical lamination
Transcriptional regulation of the pneumococcal capsule can dictate serotype-specific infection
Directional dynamics in the entorhinal cortex of male mice driven by behavioral constraints
Molecular mapping in DNA-PAINT via modified Gaussian Mixture Modeling
Abstract Super-resolution fluorescence microscopy, and specifically DNA-PAINT, provides localization precision down to ~2 nm enabling molecular-resolution imaging. To produce molecul...