Nature Communications
Articles in this Issue
Magnetic-driven multifunctional optoelectronic catheter for in vivo chemical mapping and precisely guided-tumor therapy
CF2H: a cell-free two-hybrid platform for rapid protein binder screening
Combined physical and pharmacological anabolic osteoporosis therapies increase bone response and mechanoregulation in female mice
Abstract Bone’s ability to adapt to mechanical demands is governed by mechanoregulation, the process by which cells sense and respond to mechanical stimuli to maintain skeletal integ...
A meta learning and task adaptive approach for drug target affinity prediction
Abstract Accurate and robust prediction of drug-target affinity (DTA) plays a critical role in drug discovery. While deep learning has advanced DTA prediction, existing methods strug...
Dynamic hydroxyl cycle of zeolite for short and ultra-short chain PFAS free potable water
Spin-manipulation via novel MoPS3 nanocrystal for high-performance thick-film organic solar cells
Magnetoreception in a freshwater ciliate arises from endosymbiosis
Abstract Magnetoreception is a remarkable ability found across a diverse range of organisms, including bacteria, birds, fish, insects, and mammals, enabling them...
Integrating ANI and phylogenies for re-evaluation of Fusobacterium taxonomy and disease associations
Regionalized regulation of actomyosin organization influences cardiomyocyte cell shape changes during chamber curvature formation
Abstract Cardiac chambers emerge from a heart tube that balloons and bends to create expanded ventricular and atrial structures, each containing a convex outer curvature (OC) and a r...
Textured piezoelectric ceramics with reduced grain size for high-frequency transducer applications
A foundation model for multi-task cross-distribution restoration of fluorescence microscopy images
Probing boron vacancy defects in hBN via single spin relaxometry
Abstract Spin defects in solids offer promising platforms for quantum sensing and memory due to their long coherence times and optical addressability. Here, we i...
A paired sequence language model for protein-protein interaction modeling
Abstract Understanding protein–protein interactions (PPIs) is crucial for deciphering cellular processes and guiding therapeutic discovery. While recent protein language models have...
Chirality transfer from chiral perovskite to molecular dopants via charge transfer states
A cellular basis for the hourglass pattern in vertebrate embryogenesis
Abstract Vertebrate embryogenesis follows a conserved trajectory, exhibiting divergence in early and late stages and conservation during mid-embryogenesis across species. This patter...
Wafer-scale manufacturing of ultra-broadband, high-power erbium-doped integrated lasers
Abstract Erbium (Er) is an attractive gain medium for amplifiers and lasers due to its long excited-state lifetime, low noise and nonlinearity, and temperature s...
Identification of altered immune landscape at single-cell resolution in NSCLC brain metastasis and its association with poor immune checkpoint inhibitor responses
Dual engineering of thermodynamics and kinetics in covalent organic frameworks for separation
Abstract Dual engineering thermodynamics and kinetics is crucial for achieving high-performance separation, but remains challenging. Here, we pioneer in the engineering of covalent o...
Translational regulation by oxidative desulfuration of tRNA modifications
Ancient DNA and spatial modeling reveal a pre-Inca trans-Andean parrot trade
A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma
Abstract A greater understanding of the biology of nevi will provide insights into the etiology of melanoma. Our large-scale meta-analysis of 14 nevus genome-wid...
Reconstitution of woody biomass framework via dual-functional lignin engineering toward efficient and salt-resistant solar desalination
Sororin locks the DNA-exit gate of cohesin to preserve sister-chromatid cohesion
Abstract The cohesin complex mediates sister-chromatid cohesion by topologically entrapping DNA within an SMC1-SMC3-RAD21 ring, yet how Sororin preserves cohesion beyond its known ro...
Phytochromes facilitate social behaviour in marine diatoms
Abstract The phytochrome superfamily comprises photosensory proteins that enable organisms to perceive changes in light intensity and quality and is widespread a...
Acinetobacter baumannii’s lifestyle includes soil-dwelling colonization of decaying plant material and airborne spread
Abstract Acinetobacter baumannii is a Gram-negative nosocomial pathogen that is notorious for its rapid development of antibiotic resistance....