Nature Communications
Articles in this Issue
Loss of polarity by Cdc42 depletion and oncogenic Kras activation in the mouse intestinal epithelia leads to a necrotizing enterocolitis (NEC)-like disease
Abstract Cell polarity is essential for maintaining intestinal epithelial organization and function. Here we show that combined loss of polarity by epithelial loss of Cdc42 with onco...
Multimodal ion-gated transistor based on 2D superionic conductor for in-memory computing in deep learning
Molecular mechanism of menthol-induced TRPV5 channel inhibition
Carbon, nitrogen, and sulfur cycling unveil deep-sea microbial niches in the Atacama Trench
Large-scale multi-omics profiling reveals environmental and evolutionary drivers of fungal phylogeographic and metabolic diversity
Decomposition of cross-country socioeconomic inequality in mortality by 288 causes of death and 84 risk factors from 1990 to 2021
Olfactory cleft biopsy analysis of Alzheimer’s disease pathobiology across disease stages
Mushroom biotech startups help address global challenges
An equilibrium rotator glass-forming phase for long-ranged repulsive colloidal rods
Behavioral shifts mask the success of legislation and outreach for endangered species recovery
Abstract A fundamental challenge in conservation is assessing the efficacy of recovery actions to optimize endangered species management. Considerable recent att...
Self-polymerized polyphenol-based platform for the management of dry eye pathogenesis
FGFR signaling establishes spatial gradients of secretory cell identities along the airway proximal-distal axis
Abstract Secretory cells are major structural and functional constituents of the lung airways. Their heterogeneity, spatial organization and specification mechanisms are partially un...
Solvation-mediated isomerization of surface motifs tunes emissions and electron transfer dynamics in gold nanoclusters
Efficient control of enterochromaffin versus islet differentiation from human pluripotent stem cell-derived pancreatic progenitors
Impacts of local anthropogenic stressors outpace those of climate on coral reef collapse in the northern South China Sea
Motor cortex somatostatin interneurons adaptively shape the structure of action sequences
Abstract The brain flexibly reorganizes action sequences to optimize behavioral outcomes through reinforcement learning and adaptive motor control. Although the primary motor cortex...
The hidden role of rhizospheric viruses in promoting nitrogen fixation in soils
Unlocking the reducing power of metal nitrides by mechanochemical hydrodefluorination of fluorinated compounds
Tough asymmetric thermochromic ionogels via dynamic in situ phase separation for dual-modal smart optical switching
Abstract Despite significant advances in thermochromic materials (TCMs) for smart optical switching, achieving simultaneous optimization of optical switching, me...
Spatial heterogeneity of MDSCs mediated by ANXA1-FPRs signaling drives immune suppression in OSCC progression
Decoupling electronic and geometric effects in Pd catalysts via thermal surface reconstruction for selective hydrogenation
Sub-second spin and lifetime-limited optical coherences in 171Yb3+:CaWO4
Prasugrel inhibits TLR7-driven autoimmunity in systemic lupus erythematosus by acetylating cGAS
Abstract Systemic lupus erythematosus (SLE) has a complex, multifactorial etiology, which contributes to a lack of definitive cure and limited treatment efficacy. Here, we report tha...
Rapid dynamics of dorsal raphe serotonin neurons regulate the strength of visual attention
Abstract Every moment, a spotlight of attention roams our visual field to enhance detection of salient stimuli. While recent work suggests how the brain selects salient relevant stim...
NANP targeting radiosensitizes glioblastoma through TNFR1 sialylation-driven mesenchymal shift
Abstract Glioblastoma (GBM) patients have dismal survival due to resistance to initial ionizing radiation therapy (RT). Clonal evolution analysis reveals no dominant RT-resistant clo...