Nature Communications
Articles in this Issue
Genomic inference of sites of transmission during regional spread of blaNDM Klebsiella pneumoniae in Michigan
CD177⁺ neutrophil-platelet aggregates contribute to thromboinflammation via NETs in necrotizing enterocolitis
Membrane interfacial potential governs surface condensation and fibrillation of α-Synuclein in neurons
Parkinson’s disease-associated PLA2G6 protects IP3R1 protein to control ER-mitochondria tethering and Ca2+ transfer
Abstract Mutations in the phospholipase A2 group VI ( PLA2G6 ) gene have been linked to autosomal recessive Parkinson’s d...
Coexisting kagome and heavy fermion flat bands in YbCr6Ge6
Volumetric 3D printing of a fluoropolymer and closed-loop chemical recycling of its fluorinated content
MDM2 Inhibition with Alrizomadlin (APG-115) in TP53 wild-type salivary gland cancers: a phase I clinical trial
StrucGAP: a modular, streamlined and traceable data mining platform for structural and site-specific glycoproteomics
Superacid-resistant macrocyclic BODIPYs
Abstract Boron-dipyrromethenes (BODIPYs) are versatile fluorophores with intense fluorescence and broad applications in bioimaging and sensing. However, they undergo deboronation und...
FGF1 orchestrates circadian hepatic triglyceride secretion
A snow-fire bridge mechanism for the 2025 Southern California winter wildfire
Abstract In January 2025, a rare and highly destructive wildfire devastated Southern California, becoming the costliest wildfire event in recorded history. The unusual timing of this...
Assessing the effectiveness of riparian buffers in protecting biodiversity: a meta-analysis
Tumor-specific lncRNA IGF1R-AS1 trans-regulates chromatin interactions associated with oncogenic MYC signaling
Abstract LncRNAs have emerged as pivotal regulators in the development and progression of various human cancers. However, understanding the precise mechanisms by...
The relative role of direct orbital forcing versus CO2 and ice feedbacks on Quaternary climate
Abstract During the Quaternary (the last 2.58 million years), Earth’s climate has fluctuated between glacials and interglacials, paced by external forcings and m...
Data-In-situ Computing with One-Pixel-Multiple-Memristor Architecture for Neuromorphic Sequential Vision
Abstract Neuromorphic vision systems based on memristors offer an energy-efficient approach to artificial vision, yet traditional pixel(s)-to-one-memristor architectures remain ineff...
Cryo-EM structure of TRPM1 reveals a non-canonical architecture with an inverted transmembrane domain
4polar3D single molecule imaging of 3D orientation in dense actin networks using ratiometric polarization splitting
Abstract Single Molecule Orientation and Localization Microscopy (SMOLM) aims at simultaneously measuring the position and orientation of single molecules, generating orientation-enc...
Asymmetric global urban cooling potential demands accelerated and context-specific actions
A connectivity threshold between grass patches amplifies coastal dune formation
DC-CD4 bispecific tolerogenic nanovesicles induce antigen-specific regulatory T cells and ameliorate collagen-induced arthritis in mice
Low-intensity focused ultrasound-activated piezoelectric gel bandage for diabetic wound repair and neuropathic pain relief
Paired electrolysis enables para-C–H amination of phenols with nitroarenes and mechanistic visualization via multifunctional electrochemical mass spectrometry
Bst2-targeted senotherapy restores visual function by eliminating senescent retinal cells
Abstract Senescent cells contribute to degenerative processes in multiple tissues, including the retina. In the retinal pigment epithelium (RPE), their accumulation is closely associ...
Enhancing the performance of Magnets photosensors
Abstract Photosensory protein domains, derived from nature, are foundational for optogenetic protein engineering. Tailoring their properties enables their full exploitation for optog...
RPA directly stimulates Mer3 helicase processivity to ensure normal crossover formation in meiosis
Abstract Meiotic crossover formation is critical for generating viable gametes and enhancing genetic diversity. The helicase Mer3 (HFM1 in humans) is a highly co...