Nature Communications
Articles in this Issue
A microbial platform for selective biosynthesis of monoterpene esters
Tree shrew immune cell atlas identifies NR1H3⁺ tissue macrophages with conserved anti-inflammatory function
Controlling narrowband phosphorescence and delayed fluorescence by aggregate size
CD73high fibroblasts orchestrate keratinocyte inflammation in the psoriasis-associated epithelial immune microenvironment
Heterointerface-engineered ZnO/CuO bimetallic sites enable pollutant-directed conversion with in situ catalyst regeneration
Multi-layered molecular profiling informs the diagnosis and targeted therapy of desmoplastic small round cell tumor
Abstract Desmoplastic small round cell tumor (DSRCT) is an ultra-rare sarcoma with limited treatment options. Here, we show that comprehensive molecular profiling informs diagnosis a...
Thermal Force Imaging of Hot Electrons in Operando Nanodevices
Complete inhibition of β-tryptase by tetramer dissociation and active site allostery due to a single antibody residue
High-Q multimodal guided-surface lattice resonances in index-discontinuous environments
Suppressing electron-phonon coupling in perovskite nanoplatelets for efficient pure-red light-emitting diodes with narrow spectral emission
Combining multiplexed assays of variant effect for enhanced BRCA2 variant classification
Abstract Determining the clinical relevance of BRCA2 variants of uncertain significance is critical for informed risk man...
The integrated stress response suppresses PINK1-dependent mitophagy by preserving mitochondrial import efficiency
Abstract Mitophagy is crucial for maintaining mitochondrial health, but how its levels adjust to different stress conditions remains unclear. In this study, we investigated the role...
HIV-1 uncoating location dictates sites of integration
Abstract HIV-1 cores enter the nucleus and undergo capsid disassembly (uncoating) near their integration site. Although most viral cores are localized to nuclear speckles (NSs), the...
Distinct distributed neural dynamics predict pallium-dependent social approach
Fc-free single-chain antibody mRNA therapy for airway infection of multidrug-resistant Pseudomonas aeruginosa
Rocahepevirus ratti: molecular evolution, zoonotic potential and public health impact
Deep neural network inference on an integrated, reconfigurable photonic tensor processor
Abstract Artificial neural networks set the pace in machine vision, natural language processing, and scientific discovery, but their performance depends on fast and efficient tensor...
CRISPR activation screens identify oncogenic lncRNAs that are susceptible to CDK4/6 inhibitor treatment
Vitamin B12 induces memory of predation through vitellogenin provisioning
Abstract Nutritional effects on trait inheritance are widespread in animals including human famines, representing some of the most severe environmental influence...
Amphibole reaction rims record shear during magma ascent
Abstract Mineral reaction textures are fundamental archives of geological change. Amphibole reaction rims are among the most widely used to reconstruct pre-eruptive magmatic conditio...
Brain functional-structural gradient coupling reflects development, behavior and genetic influences
Abstract Gradients provide low-dimensional representations of macroscale brain organization, yet how structural-functional gradient coupling develops and relates to behavioral and mo...