Journal of Clinical Oncology
Articles in this Issue
Economic analysis of first-line treatment for advanced melanoma in a public hospital.
e13618 Background: Access to immune checkpoint inhibitors (ICIs) for advanced cutaneous melanoma remains constrained in Br...
Predictors of survival of patients with cancer-associated thrombosis: Experience from a tertiary hospital in Sub-Saharan Africa.
e24127 Background: Cancer significantly increases the risk of thrombosis. Recent advances in cancer treatment may have led...
Impact of adverse social determinants of health on long-term mortality and comorbidities in patients with cancers of the lip, oral cavity, and pharynx: A propensity score–matched cohort study using federated electronic health records.
e18124 Background: Social determinants of health (SDOH), encompassing socioeconomic and environmental factors, are pivotal...
Chemotherapy, endocrine therapy, and cognitive impairment in long-term breast cancer survivors.
523 Background: Chemotherapy and endocrine therapy have known neurobiological effects, yet evidence on their associations...
Comparative outcomes in chronic lymphocytic leukemia patients with and without myasthenia gravis: A propensity score–matched analysis.
e19019 Background: Chronic lymphocytic leukemia (CLL) is commonly associated with autoimmune complications, most of which...
Evaluation of intervention strategies to improve follow-up after FIT/FOBT tests: A systematic review and meta-analysis.
10549 Background: Colorectal cancer (CRC) is the third most common cancer worldwide, with the majority of patients diagnos...
Uptake of screening breast MRI in high-risk patients without a personal history of breast cancer.
e13527 Background: Early detection of breast cancer reduces breast cancer mortality. Women at higher-than-average risk for...
Evaluation of homologous recombination deficiency (HRD) in gastric cancer: Real-world prevalence and outcomes with first-line (1L) platinum-based therapy.
4039 Background: Metastatic gastric and gastroesophageal junction cancers (GC/GEJ) have poor outcomes with limited predict...
An open-label, randomized phase 2 trial of ramucirumab and pembrolizumab versus pembrolizumab as first-line therapy for PD-L1–positive, recurrent or metastatic head and neck squamous cell carcinoma (RM-HNSCC).
6026 Background: Vascular endothelial growth factor (VEGF) is commonly overexpressed in head and neck squamous cell carcin...
Inpatient national mortality analysis in hospitalized patients with cancer diagnoses using machine learning.
e13686 Background: In-hospital mortality among hospitalized patients with cancer diagnoses remains a major clinical and he...
MajesTEC-9: A phase 3 randomized study of teclistamab monotherapy vs investigator’s choice of pomalidomide, bortezomib, and dexamethasone or carfilzomib and dexamethasone (PVd/Kd) in patients (pts) with relapsed refractory multiple myeloma (RRMM).
7507 Background: Triplet and quadruplet regimens have greatly improved outcomes in newly diagnosed multiple myeloma, yet a...
Local delivery of SN-38 using a biodegradable implantable membrane for treatment of glioblastoma.
e14100 Background: Glioblastoma (GBM) remains a lethal disease with high rates of local recurrence despite maximal surgica...
Efbemalenograstim alfa for prophylaxis in non–small cell lung cancer patients patients with chemotherapy-induced febrile neutropenia: A randomized, multicenter, exploratory clinical trial.
8657 Background: Neutropenia is a common dose-limiting chemotherapy toxicity, with its severity and duration impairing the...
Identifying drivers of early readmission in cancer patients to improve care and outcomes.
e23295 Background: Cancer patients are at increased risk for hospital readmission, which adversely affects outcomes and bu...
Association of GLP-1 receptor agonist exposure with mortality, infectious, and hematologic outcomes in chronic lymphocytic leukemia: A real-world retrospective TriNetX study.
e18591 Background: Emerging studies show that Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) might have antineoplas...
Real-world data on clinical profile of immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs) in oncology.
11151 Background: Immune checkpoint inhibitors (ICIs) are widely used in cancer, and are associated with immune-related ad...
All that glitters is not gold: The importance of ruling out other causes of leptomeningeal enhancement on MRI that may resemble leptomeningeal disease (LMD).
e14018 Background: Leptomeningeal metastatic disease (LMD) is increasingly common entity which at times, in the proper cli...
Long-term survival, recurrence patterns, and postrecurrence outcomes after neoadjuvant chemoradiotherapy versus surgery plus adjuvant therapy in locally advanced esophageal squamous cell carcinoma: Final results of a randomized phase III trial.
e16092 Background: The optimal treatment strategy for locally advanced esophageal squamous cell carcinoma (ESCC) remains u...
Closing the information gap in oncology: A retrieval-augmented generation multi-modal AI platform for personalized patient education and physician efficiency.
11075 Background: Effective patient education is critical in oncology but hindered by the complexity of treatment guidelin...
Sensory neuropathy and neuropathic pain during taxane chemotherapy in CIPN-free patients.
e24186 Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common toxicity of taxane chemotherapy and inclu...
Partial breast irradiation followed by neoadjuvant immunochemotherapy in early TNBC.
e12649 Background: Neoadjuvant immunochemotherapy (NAICT) incorporating immune checkpoint blockade has become standard for...
Effects of microplastics on the colorectal tumor immune microenvironment and immunotherapy resistance via JAK–STAT–microbiota perturbation.
e15731 Background: Microplastics (MPs) are pervasive environmental pollutants with rising human exposure. Although potenti...
Zanubrutinib plus rituximab as front-line treatment for mucosa-associated lymphoid tissue (MALT) lymphoma: A single-arm, phase II study (ZAMA).
7080 Background: Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common subtype of marginal zone lymphoma an...
KEYNOTE-B59: An open-label, multicenter, phase 1/2 study of efdelikofusp alfa (GI-101A; CD80-IgG4 Fc-IL2v2) in advanced solid tumors (part E & F of GII-101-P101).
2519 Background: Efdelikofusp alfa is a novel immunocytokine consisting of CD80 fused to an engineered IL-2 variant (IL-2v...
Efficacy of adjuvant S-1 vs capecitabine plus oxaliplatin (XELOX) chemotherapy among gastric cancer patients after D2 gastrectomy: A systematic review and meta-analysis.
e16115 Background: Adjuvant chemotherapy improves outcomes after D2 gastrectomy for gastric cancer. S-1 and XELOX are comm...