Journal of Clinical Oncology
Articles in this Issue
Molecular progression defined by longitudinal ctDNA dynamics for prediction of outcomes in immune checkpoint inhibitor–treated solid tumors.
2572 Background: Reliable early biomarkers of immune checkpoint inhibitor (ICI) resistance remain an unmet need due to del...
The neo-epitope-based vaccine OSE2101 with or without pembrolizumab versus best supportive care as maintenance in platinum-sensitive recurrent ovarian cancer patients with controlled disease after platinum-based chemotherapy: The academic randomized TEDOVA/GINECO-OV244b/ENGOT-ov58 trial.
5510 Background: OSE2101 is a neo-epitope vaccine targeting 5 tumor-associated antigens (TP53, MAGE2, MAGE3, CEA and HER2)...
Validation of Immunoscore for prognostic stratification in HPV-associated oropharyngeal cancer: An international multicenter study.
6077 Background: Treatment optimization in HPV-associated oropharyngeal cancer (OPSCC) remains challenging due to the limi...
Epimedin A to prevent glioblastoma growth and invasion.
e14078 Background: Glioblastomas (U87) are an aggressive brain tumor that arises from glial cells and invades surrounding...
Heart failure–related mortality among U.S. liver and intrahepatic bile duct cancer patients: A 25-year CDC WONDER analysis.
e16220 Background: Liver and intrahepatic bile duct cancer (L/IBDC) is a leading cause of cancer mortality worldwide. Como...
Prognosis of mediastinal lymph node metastases in pediatric patients with osteosarcoma and lung metastases.
e22006 Background: Metastasectomy is recommended for select pediatric patients with osteosarcoma with resectable pulmonary...
Late hematological toxicity after chemotherapy: Exome analysis with long-term follow-up in Mexican population.
e24145 Background: Genomic alterations chemotherapy-induced are associated with cytopenias, myelodysplasia, or acute leuke...
Advancing career-focused training: Program leader perspectives on professional development pathways in hematology/oncology fellowships.
9008 Background: Hematology/Oncology (H/O) fellows have diverse career opportunities post-graduation. Many fellowship prog...
Clonal hematopoiesis in head and neck carcinomas receiving immunotherapy.
6064 Background: Clonal hematopoiesis (CH) is an age-related accumulation of somatic genetic alterations in hematopoietic...
Smoking signature as used to define a genomically distinct subset of class I BRAF-mutant NSCLC.
8538 Background: Class I BRAF mutant ( BRAF...
Associated antitumor effects of oncoytic vaccinia virus expressing a tethered IL-12/IL-2 fusion cytokine.
e14557 Background: Cancer immunotherapy has revolutionized cancer treatment, but many solid tumors remain non-inflamed and...
Proton or photon? Comparative survival and toxicity outcomes in lung cancer radiotherapy: A systematic review and meta-analysis.
e20048 Background: Radiotherapy (RT) is a cornerstone in non-small cell lung cancer (NSCLC) management. Conventional photo...
Cerebrovascular mortality in patients with head and neck cancer in the United States, 1999-2023: A population-based analysis.
e18106 Background: Survival gains in head and neck cancer (HNC) have increased the importance of non-cancer mortality in o...
A multicenter, randomized phase Ib trial to evaluate neoadjuvant immunotherapy combination of nivolumab alone or plus ipilimumab with the IL-2 superkine MDNA11 alone or with tocilizumab in patients with high-risk, surgically resectable melanoma: The NEO-CYT trial.
TPS9612 Background: Neoadjuvant immunotherapy, administered upfront of surgery in patients with resectable stage III melan...
Clinicopathologic and imaging predictors of pathologic complete response after neoadjuvant chemoimmunotherapy in resectable NSCLC: A systematic review and meta-analysis.
e20068 Background: Neoadjuvant chemoimmunotherapy (CIT) improves pathologic complete response (pCR) rates in resectable no...
Racial and ethnic disparities in breast cancer care: Barriers associated with treatment delays.
e12706 Background: Breast cancer is one of the most common cancers among women. Yet, disparities in access to a timely dia...
Prognostic impact of estrogen and progesterone receptor expression disparity in early-stage HR+/HER2- breast cancer.
e12534 Background: In hormone receptor-positive, HER2-negative early-stage breast cancer (HR+/HER2- EBC), the biological c...
Impact of remote symptom monitoring program on payor-specific healthcare costs.
1632 Background: Remote symptom monitoring (RSM) programs are currently being implemented across oncology practices nation...
Real-world treatment patterns and survival outcomes in splenic marginal zone lymphoma: A SEER analysis (2000-2022).
e19096 Background: Splenic marginal zone lymphoma (SMZL) is a rare, indolent B-cell non-Hodgkin lymphoma with heterogeneou...
Comparative effectiveness of pembrolizumab and nivolumab as first-line treatment for advanced/unresectable or metastatic melanoma: A propensity-score adjusted analysis from a US national health system.
e21513 Background: Therapies targeting programmed cell death protein 1 (PD1) are mainstays of modern cancer therapy. Pembr...
Longitudinal changes in pulmonary function following multiple courses of thoracic radiotherapy.
e20103 Background: Pulmonary function decline following thoracic radiotherapy (RT), particularly DLCO, is well documented...
Improving resident education in ambulatory oncology: A novel flipped-classroom curriculum for internal medicine residents.
e21009 Background: There is a paucity of oncology curricula for internal medicine (IM) residents, particularly related to...
Assessing the performance of ChatGPT in addressing ethical dilemmas in oncology.
e23292 Background: Large language models such as ChatGPT have been shown to demonstrate accuracy in diagnostic reasoning a...
Clinical outcomes of gabapentinoids for oncologic pruritus: A retrospective cohort study.
12066 Background: Pruritus is a debilitating symptom in oncologic patients, sometimes leading to interruption of cancer th...
Escalating site burden and cost: What’s driving the surge in oncology investigator grants over the past decade.
e23149 Background: Publicly accessible data and industry analyses strongly confirm that site costs, including investigator...