Journal of Clinical Oncology
Articles in this Issue
Prevalence of non-treatment following pancreatic cancer diagnosis in the United States: A population-based analysis, 2016–2022.
e16357 Background: Pancreatic cancer is an aggressive malignancy for which cancer-directed therapy can improve outcomes wh...
Spatial localization of epithelial-mesenchymal transition and immune niches in non-small cell lung cancer via interpretable gene set activity analysis.
e20556 Background: The tumor microenvironment (TME) in non-small cell lung cancer (NSCLC) is highly heterogeneous, with sp...
Indocyanine green fluorescence–guided navigation during gastrectomy for resectable gastric cancer: A systematic review and meta-analysis.
e16147 Background: Radical gastrectomy with lymphadenectomy is the standard surgical approach for curative treatmentof gas...
Enhanced predictive value of KELIM for surgical resectability in HRD-positive high-grade serous ovarian cancer.
5590 Background: Neoadjuvant chemotherapy followed by interval debulking surgery is commonly used in the management of adv...
EfficientNetV2-guided knowledge distillation for breast ultrasound diagnosis: Scalable deep learning with international clinical validation.
e12571 Background: Breast cancer remains a leading cause of cancer-related morbidity worldwide, with imaging central to ea...
Major adverse cardiovascular events among prostate cancer patients in the VA, stratified by HIV status and androgen deprivation therapy.
12157 Background: Despite the rapidly increasing trend in incidence of prostate cancer among persons with HIV (PWH), compr...
Total neoadjuvant immunotherapy plus chemotherapy in Borrmann type IV gastric cancer (PERISCOPE-01 study): An open-label, single-arm, phase 2 trial.
4079 Background: Borrmann type IV (Borrmann-IV) gastric cancer (GC), or linitis plastica, is marked by diffuse infiltratio...
Real-world efficacy and safety of tarlatamab in small cell lung cancer and extrapulmonary neuroendocrine carcinoma.
e20166 Background: Patients with extensive-stage small cell lung cancer (ES-SCLC) and extrapulmonary neuroendocrine carcin...
Patterns of failure and efficacy for unresectable or recurrent gastric and gastroesophageal junction adenocarcinoma after immune checkpoint inhibitor therapy: A retrospective study.
e16491 Background: Immune checkpoint inhibitors (ICIs) combined with chemotherapy have been incorporated into clinical gui...
Clinical outcomes of local treatments for oligoprogressive or oligorecurrent small cell lung cancer.
8090 Background: The role of local treatments in patients with oligoprogressive or oligorecurrent small cell lung cancer (...
Intersecting risks: Myelodysplastic neoplasms and cardiovascular disease mortality in older adults across the United States, 1999–2020.
e18581 Background: Myelodysplastic syndrome (MDS) predominantly affects older adults and carry substantial mortality. Card...
Limitations in US cancer screening rate data and opportunities for improvement.
e22535 Background: Cancer screening is a cornerstone of cancer control, yet screening participation remains inconsistent a...
Predicting infiltrative hepatocellular carcinoma and efficacy of combination treatment for conversion therapy based on pretreatment CT/MR features.
e16290 Background: Infiltrative HCC (iHCC) has been demonstrated to exhibit the highest malignant potential and poorest pr...
ASPRIA: A single-arm phase 2 trial of atezolizumab with sacituzumab govitecan to prevent recurrence in triple-negative breast cancer.
TPS644 Background: Despite marked improvements in neoadjuvant chemoimmunotherapy (NACT) and adjuvant treatment for patient...
Palliative neck radiation therapy (RT) in combination with lenvatinib/pembrolizumab (L/P) in BRAF wild-type anaplastic thyroid cancer (BRAF-WT ATC).
6117 Background: BRAF-WT ATC carries a poor prognosis due to limited effective therapies and rapid, often fatal locoregion...
Conditional survival in advanced-stage epithelial ovarian cancer: Implications for survivorship planning and patient counseling.
e17500 Background: Advanced-stage epithelial ovarian cancer (EOC) is characterized by biological heterogeneity and...
Cytokine profiles in HPV-associated cervical intraepithelial neoplasia.
e22517 Background: Persistent high-risk human papillomavirus (HPV) infection is a well-established driver of cervical intr...
Safety and efficacy results from a first-in-human, phase 1/2 study of ASKG915, an anti-PD-1/pro-IL-15 bifunctional fusion protein, for patients with advanced solid tumors.
2607 Background: ASKG915 is a bifunctional fusion protein of PD-1 antibody fused with an IL-15 prodrug. Preclinical studie...
A phase 3 trial of adagloxad simolenin/OBI-821 in patients with high-risk early-stage triple-negative breast cancer.
2551 Background: Adagloxad simolenin (AS) is a therapeutic cancer vaccine composed of Globo H linked to the carrier protei...
Impact of remote therapeutic monitoring on time to discontinuation and acute care events among patients treated with immune checkpoint inhibitors.
11108 Background: Immune checkpoint inhibitors (ICI) are used to treat several solid tumors but can cause serious toxiciti...
Factors associated with mood and anxiety disorders in cancer survivors: A systematic review and meta-analysis.
e24106 Background: Mood and anxiety disorders affect up to 38% of cancer survivors and are associated with poorer quality...
Safety and preliminary efficacy of a novel armored mesothelin-targeted CAR-T therapy in advanced solid tumors.
2543 Background: UCMYM802 is an autologous mRNA-electroporated CAR-T cell therapy targeting mesothelin (MSLN), incorporati...
Lipid-lowering therapy use among cancer survivors undergoing lung cancer screening: A cross-sectional analysis.
12029 Background: Cardiovascular disease (CVD) causes 56% of non-cancer deaths among cancer survivors, yet lipid-lowering...
First-line maintenance therapy patterns in <i>BRCA</i> wild-type and HRD-negative advanced epithelial ovarian cancer: A European real-world study.
e17552 Background: Maintenance therapy is central to the management of advanced epithelial ovarian cancer (AEOC), yet real...
Uterine serous and clear cell carcinomas: Hormonal profile and expression of steroid hormone receptors in mitochondria.
e17624 Background: Uterine serous carcinoma (USC) and clear cell carcinoma (CCC) are rare but aggressive histological subt...