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E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2

Journal of Biological Chemistry Tianyi Wu, Fengli Jiang, Fan Wu et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108027

m6A ‘encodes’ a dedicated mRNA decay pathway

Nature Reviews Molecular Cell Biology Eytan Zlotorynski Jan 01, 2025 DOI: 10.1038/s41580-024-00815-y

Science in 2025: what to expect this year

Nature Benjamin Thompson, Miryam Naddaf Jan 01, 2025 DOI: 10.1038/d41586-024-04237-w

The mechanism of Ca2+-independent activation of BKCa channels in mouse inner hair cells and the crucial role of the BK channels in auditory perception

Journal of Biological Chemistry Zhong-Shan Shen, Jun Gan, Bing Xu et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.107970

Quiescent cells maintain active degradation-mediated protein quality control requiring proteasome, autophagy, and nucleus-vacuole junctions

Journal of Biological Chemistry Dina Franić, Mihaela Pravica, Klara Zubčić et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108045

Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells

Journal of Biological Chemistry Manon Garcia, Hélène Holota, Angélique De Haze et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108022

Three decades of protein-fragment complementation

Nature Reviews Molecular Cell Biology Stephen W. Michnick Jan 01, 2025 DOI: 10.1038/s41580-024-00813-0

An anomalous abundance of tryptophan residues in ceramide synthases based on analysis of all membrane proteins in the Swiss-Prot database

Journal of Biological Chemistry Beatriz Mestre, Iris D. Zelnik, Stav Izrailov et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108053

Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment

Nature Reviews Molecular Cell Biology Xiaofu Cao Jan 01, 2025 DOI: 10.1038/s41580-024-00808-x

Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors

Journal of Biological Chemistry Thomas C. Eadsforth, Leah S. Torrie, Paul Rowland et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108049

Paleoproteomics sheds light on million-year-old fossils

Nature Reviews Molecular Cell Biology Ryan Sinclair Paterson, Palesa Petunia Madupe, Enrico Cappellini Jan 01, 2025 DOI: 10.1038/s41580-024-00803-2

Reactivation and long-term stabilization of the [NiFe] Hox hydrogenase of Synechocystis sp. PCC6803 by glutathione after oxygen exposure

Journal of Biological Chemistry Merle Romig, Marie Eberwein, Darja Deobald et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108086

Connecting cells through TNT

Nature Reviews Molecular Cell Biology Lisa Heinke Jan 01, 2025 DOI: 10.1038/s41580-024-00811-2

Misfolding of transthyretin in vivo is controlled by the redox environment and macromolecular crowding

Journal of Biological Chemistry Sanduni Wasana Jayaweera, Melisnur Sahin, Fabian Lundkvist et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108031

Chaperone-mediated disaggregation of infectious prions releases particles that seed new prion formation in a strain-specific manner

Journal of Biological Chemistry Daniel Shoup, Suzette A. Priola Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108062

The globular domain of extracellular histones mediates cytotoxicity via membrane disruption mechanism

Journal of Biological Chemistry Yixuan Pan, Mengyuan Peng, Mindan Tong et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108038

Downregulation of the splicing regulator NSRP1 confers resistance to CDK4/6 inhibitors via activation of interferon signaling in breast cancer

Journal of Biological Chemistry Shiyi Yu, Yue Si, Miao Xu et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108070

β1-integrin controls IGF-1R internalization and intracellular signaling

Journal of Biological Chemistry Niamh McDermott, Stephen O’Shea, Leonie Rieger et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108021

Interplay of niche and respiratory network in shaping bacterial colonization

Journal of Biological Chemistry Stuti Srivastav, Arpita Biswas, Amitesh Anand Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108052

Proteomic study identifies Aurora-A–mediated regulation of alternative splicing through multiple splicing factors

Journal of Biological Chemistry Arun Prasath Damodaran, Olivia Gavard, Jean-Philippe Gagné et al. Jan 01, 2025 DOI: 10.1016/j.jbc.2024.108000