Browse Articles

Discover research articles across all indexed journals

Identification and correction of phase delay errors for hemispherical resonator gyroscopes

Scientific Reports Youhuan Ning, Changhong Wang, Boqi Xi et al. Jan 15, 2025 DOI: 10.1038/s41598-025-86288-1

Selective Protein (Post-)modifications through Dynamic Covalent Chemistry: Self-activated S<sub>N</sub>Ar Reactions

Journal of the American Chemical Society Ferran Esteve, Jean-Louis Schmitt, Sergii Kolodych et al. Jan 15, 2025 DOI: 10.1021/jacs.4c15421

Single-cell bilayer design of a terahertz six-channel metasurface for simultaneous holographic and grayscale images

Scientific Reports Zhiqiang Du, Chunhui Zhu, Zhengyong Song Jan 15, 2025 DOI: 10.1038/s41598-025-86319-x

Structural Basis of High-Precision Protein Ligation and Its Application

Journal of the American Chemical Society Kelvin Han Chung Chong, Lichao Liu, Rae Chua et al. Jan 15, 2025 DOI: 10.1021/jacs.4c10689

Study of endophytic fungi of Ipomoea pes-caprae reveals the superiority of in situ plant conservation over ex situ conservation from a mycological view

Scientific Reports Yu-Hung Yeh, Roland Kirschner Jan 15, 2025 DOI: 10.1038/s41598-025-86508-8

Effects of Cofeeding Hydrogen on Propane Dehydrogenation Catalyzed by Isolated Iron Sites Incorporated into Dealuminated BEA

Journal of the American Chemical Society Afnan Alghannam, Alexis T. Bell Jan 15, 2025 DOI: 10.1021/jacs.4c12344

A preliminary evaluation of a fast, low-cost, and high-throughput nucleic acid extraction method for bacterial microbiota profiling in low-microbial biomass samples

Scientific Reports Xiangning Bai, Simon Rayner, Linda Ellevog Skuggen et al. Jan 15, 2025 DOI: 10.1038/s41598-024-84682-9

Abstract The respiratory tract is colonized with low-density microbial communities, which have been shown to impact human respiratory health through microbiota–host interactions. However, a lack of fast and cost-effective nucleic acid extraction method for low-microbial biomass samples hinders investigation of respiratory microbiota. Here, we performed a pilot study to assess the suitability of the NAxtra nucleic acid extraction protocol for profiling bacterial microbiota in respiratory samples. A small number of nasopharyngeal aspirate (n = 8), nasal swab (n = 8), and saliva samples (n = 8) were collected, nucleic acids were isolated using the NAxtra protocol, and 16 S rRNA gene sequencing was performed to characterize bacterial microbiota, which were compared to the same sample types from previous studies using other protocols. The bacterial composition in nasal and saliva samples were consistent with previous reports. Saliva microbiota was significantly richer than nasal microbiota and varied less among individual samples than nasal microbiota. Bacterial composition in nasal samples was distinct from nasopharyngeal aspirates, but closer to saliva samples. A sequencing depth of 50,000 reads/sample was sufficient for microbiota profiling in low biomass respiratory samples. Our pilot study indicates the potential of the NAxtra protocol for bacterial microbiota characterization of low-microbial biomass samples and supports a more comprehensive study to fully evaluate the value of the NAxtra protocol in microbiota research and clinical diagnostics of respiratory pathogens.

Glycan Sequencing Based on Glycosidase-Assisted Nanopore Sensing

Journal of the American Chemical Society Guangda Yao, Bingqing Xia, Fangyu Wei et al. Jan 15, 2025 DOI: 10.1021/jacs.4c12940

Unsupervised domain adaptation teacher–student network for retinal vessel segmentation via full-resolution refined model

Scientific Reports Kejuan Yue, Lixin Zhan, Zheng Wang Jan 15, 2025 DOI: 10.1038/s41598-024-83018-x

An Ultramicroporous Physisorbent Sustained by a Trifecta of Directional Supramolecular Interactions

Journal of the American Chemical Society Alan C. Eaby, Shaza Darwish, Shi-Qiang Wang et al. Jan 15, 2025 DOI: 10.1021/jacs.4c13797

Cost-effectiveness analysis of eribulin versus dacarbazine in patients with advanced liposarcoma

Scientific Reports Miaomiao Zhang, Jinlong Huang, Xiaochun Zheng et al. Jan 15, 2025 DOI: 10.1038/s41598-024-84247-w

Dynamic Features Driven by Stochastic Collisions in a Nanopore for Precise Single-Molecule Identification

Journal of the American Chemical Society Jia Wang, Shao-Chuang Liu, Zheng-Li Hu et al. Jan 15, 2025 DOI: 10.1021/jacs.4c13664

New geographic information system based sustainability metric for isolated photovoltaic systems

Scientific Reports Rasha Elazab, Mohamed Daowd Jan 15, 2025 DOI: 10.1038/s41598-025-85222-9

Abstract The integration of photovoltaic (PV) technologies is vital for achieving sustainable energy solutions in isolated systems. However, A critical challenge that remains is maintaining the sustainability of these systems under the fluctuating conditions of solar irradiance, which is key for isolated energy systems. This study hypothesizes that the sustainability of PV systems can be accurately assessed through a new metric that incorporates performance consistency, variability, and resilience, using real-time energy production data alongside GIS-based solar radiation models. By analyzing fixed PV, concentrated PV (CPV), and dual axis tracking PV (DATPV) systems over a three-year period (2017–2019), The analysis indicates that DATPV systems achieved the highest energy output, with energy ratios exceeding 300% in 2019, though this was accompanied by substantial variability in performance. Fixed PV systems demonstrated the most stable performance, with a consistency term reaching 0.93 and a sustainability score of 0.87 in 2019. CPV systems performed moderately, with a sustainability score of 0.66 in 2017. These results highlight the trade-off between energy capture and operational stability, which is critical for sustainable energy management in isolated systems.

Spatiotemporal Spectroscopy of Fast Excited-State Diffusion in 2D Covalent Organic Framework Thin Films

Journal of the American Chemical Society Laura Spies, Alexander Biewald, Laura Fuchs et al. Jan 15, 2025 DOI: 10.1021/jacs.4c13129

An improved SPWM control approach with aid of ant lion optimization for minimizing the THD in multilevel inverters

Scientific Reports Alaa M. Abdel-hamed, Abdelrahman M. Nasser, Hamdy Shatla et al. Jan 15, 2025 DOI: 10.1038/s41598-024-84678-5

Abstract This article presents an innovative asymmetric multilevel inverter (MLI) topology that outperforms conventional counterparts. The introduced topology presents a breakthrough in implementing power electronics control by maximizing specific levels while minimizing switching components. A cutting-edge control scheme for optimal operation of the cascaded half-bridge MLI is presented. The ant lion optimization (ALO) algorithm was implemented to optimize the switching control to reduce the total harmonic distortion (THD) and improve power quality. For verification, the performance and effectiveness of the ALO technique are assessed by comparing its results to those obtained using the simplified sinusoidal pulse width modulation (SSPWM) technique, genetic algorithm (GA), and particle swarm optimization (PSO) in existing literature. Simulation results verified the efficacy of ALO in finding the optimal parameters. The suggested method showcases a remarkable reduction in the THD compared to SSPWM. The quality of the resulting waveform was enhanced, and both filter size and cost were significantly reduced. To meet stringent IEEE standards, an LC filter has been designed with minimal size and proper requirements. Experimental results validation of the suggested scheme, using a dSPACE R&amp;D controller board unequivocally, confirmed its robustness and effectiveness. This groundbreaking study not only introduces a superior asymmetric MLI topology but also validates its exceptional performance through comprehensive analysis and experimentation. The experimental waveforms showed good matching with the simulation outcomes. The findings hold immense promise for advancing the field of power system control and revolutionizing the designing and implementation of efficient and cost-effective inverter systems.

Dual Inhibitors of SARS-CoV-2 3CL Protease and Human Cathepsin L Containing Glutamine Isosteres Are Anti-CoV-2 Agents

Journal of the American Chemical Society Vivek Kumar, Jiyun Zhu, Bala C. Chenna et al. Jan 15, 2025 DOI: 10.1021/jacs.4c11620

Development of an interpretable machine learning model based on CT radiomics for the prediction of post acute pancreatitis diabetes mellitus

Scientific Reports Xiyao Wan, Yuan Wang, Ziyi Liu et al. Jan 15, 2025 DOI: 10.1038/s41598-025-86290-7

Succinate Nanomaterials Boost Tumor Immunotherapy via Activating Cell Pyroptosis and Enhancing MHC-I Expression

Journal of the American Chemical Society Pan Zheng, Guanglei Wang, Bin Liu et al. Jan 15, 2025 DOI: 10.1021/jacs.4c09566

Optimizing ternary hybrid nanofluids using neural networks, gene expression programming, and multi-objective particle swarm optimization: a computational intelligence strategy

Scientific Reports Tao Hai, Ali Basem, As’ad Alizadeh et al. Jan 15, 2025 DOI: 10.1038/s41598-025-85236-3

N-Doped Zigzag-Type Aromatic Truncated Cone Belts

Journal of the American Chemical Society Jia-Hui Chen, Teng-Yu Huang, Shuo Tong et al. Jan 15, 2025 DOI: 10.1021/jacs.4c11468