Browse Articles

An ensemble learning model to predict lymph node metastasis in early gastric cancer

Serum uric acid to high-density lipoprotein cholesterol ratio predicts all-cause mortality in adults with metabolic dysfunction associated steatotic liver disease

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the most prevalent chronic metabolic diseases worldwide. While serum uric acid (SUA) and high-density lipoprotein cholesterol (HDL) are individually associated with the development of MASLD, the prognostic effect of the UA, HDL and SUA-to-HDL ratio (UHR) on the all-cause mortality of MASLD patients remains unexplored. This study utilized data from 4280 MASLD patients in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. UHR was calculated by dividing SUA by HDL, and its association with all-cause mortality was assessed using Cox proportional hazards models. Adjustments were made for demographic, lifestyle, and clinical factors. A one-standard-deviation increase in UA or UHR was associated with a 19% (HR 1.19, 95% CI 1.08–1.31, P < 0.001) or 18% (HR 1.18; 95% CI 1.07–1.30; P < 0.001) higher risk of all-cause mortality of MASLD participants respectively, while no association was found between HDL and mortality. SUA and UHR are promising predictors of all-cause mortality in MASLD patients, offering clinicians a valuable biomarker for related risk stratification. Its inclusion in clinical assessments could guide interventions and improve prognosis, advancing management for MASLD patients.

Promoting the remediation of contaminated soils using biochar in combination with bioaugmentation and phytoremediation techniques

Sex-specific spirometry effects of adult COPD polygenic score in children with asthma

Distribution, scaling, and depiction of the temporal branches of the facial nerve

Encapsulation of L. fermentum with chitosan-alginate enhances its bioactivity against acrylamide toxicity in D.mel

Estimation of common breaks in linear panel data models via screening and ranking algorithm

Assessment of continuous positive airway pressure effect on the circadian clock signaling pathway in obstructive sleep apnea patients

Assigning Surface Hole Polaron Configurations of Titanium Oxide Materials to Excited-State Optical Absorptions

Associations among air pollution, asthma and lung function: a cross-sectional study

World’s tiniest pacemaker could revolutionize heart surgery

Investigations on whether image-sharpening algorithm can improve the determination of severity of diabetic retinopathy in ultra-widefield fundus photographs

Time-optimal path parameterization planning for automatic fiber placement based on reachability quadratic analysis

Restoring the Redox and Norepinephrine Homeostasis in Mouse Brains Promotes an Antidepressant Response

A waveform engineering approach for class F operation in a class C biased peaking branch of GaN MMIC Doherty power amplifiers

Modulation of immune gene expression profile in Labeo catla with chronic toxicity to emerging endocrine disruptors through a multiorgan approach

Associations between past infectious mononucleosis diagnosis and 47 inflammatory and vascular stress biomarkers

Unraveling the Kinetics of Hydride Formation and Decomposition at Pd–Au Bimetallic Interfaces: A Combined Spectroscopic and Computational Study

A progressive wafer scale approach for Sub-10 nm nanogap structures

A toolkit for seeing how the fly brain’s visual system works