Browse Articles

Grassland ecological compensation accounting based on the flow of emergy ecological products: a case from the Qinghai Tibet region, China

Daily briefing: Spouses tend to share the same psychiatric disorders

The glycosyltransferase ALG3 is an AKT substrate that regulates protein N-glycosylation

Research on real-time detection of fabric defects based on an improved Elo rating algorithm

Inositol (1,4,5)-trisphosphate 5-phosphatase promotes survival of uveal melanoma by regulating oncogenic G protein–driven calcium oscillations

Amorphous Nitride‐chloride Solid‐State Electrolytes for High Performance All‐Solid‐State Lithium Batteries

Abstract High‐performance solid‐state electrolytes (SSEs) are crucial for advancing all‐solid‐state batteries (ASSBs). Amorphous SSEs, in particular, offer promising advantages due to their grain‐boundary‐free nature, which facilitates intimate solid‐to‐solid contact and uniform lithium‐ion flux, thereby improving composite electrode performance. Here, we report a class of SSEs based on a nitrogen–chlorine dual‐anion framework, formulated as Li 3 x +0.1 ZrN x Cl 4.1 , for high‐voltage ASSBs. Unlike widely studied crystalline Li 2 ZrCl 6 with a triclinic structure, increased N 3− substitution drives a structural transition to an amorphous phase (Li 1.3 ZrN 0.4 Cl 4.1 ), which achieves a significant enhancement in Li + conductivity from 0.46 to 3.01 mS cm −1 , alongside improved oxidative stability up to 4.8 V. This dual‐anion SSEs exhibits excellent compatibility with high‐energy LiNi 0.83 Co 0.06 Mn 0.11 O 2 (NCM83) cathodes. The corresponding full cells deliver a high reversible capacity of 200.1 mAh g −1 at 4.5 V with outstanding capacity retention of 95.1% after 150 cycles at 0.2 C, along with remarkable long‐term cycling stability exceeding 3000 cycles at 3 C. Furthermore, the electrochemical stability of Li 1.3 ZrN 0.4 Cl 4.1 in conjunction with NCM83 is still preserved under elevated temperatures (50  °C) and higher cut‐off voltages (up to 4.8 V). These results highlight the promise of dual‐anion amorphous electrolytes, paving the way for the design of next‐generation SSEs beyond traditional single‐anion systems.

Some novel optical pulses in hydrodynamical nonlinear complex equation using M-truncated fractional derivative

The grant lottery: award rates at UK national funding agency fall below 20%

Robust Imidazole‐Linked 2D Covalent Organic Frameworks for Efficient Electrochemical Sodium‐Ion Storage

Abstract Exploring stable and functional linkages through facile one‐pot cyclocondensation reactions represents one of the frontiers in the development of covalent organic frameworks (COFs), which can enhance structural robustness and diversity while broadening their application potential. In this study, we report a facile synthetic strategy using p ‐toluenesulfonic acid (PTSA) as a proton mediator to construct two imidazole‐linked COFs (TABQ‐COF and TAPT‐COF) via one‐pot cyclocondensation of aromatic aldehydes with ortho ‐diamines. These two COFs not only possess good crystallinity but also exhibit excellent physicochemical stability and contain abundant redox‐active sites, which endows them with charming advantages for electrochemical energy storage. Remarkably, when employed as an anode material for sodium‐ion batteries (SIBs), TAPT‐COF delivered a reversible capacity of 517 mAh g −1 at 0.05 A g −1 while maintaining outstanding cycling stability with minimal capacity degradation (<0.035% per cycle) over 1000 cycles at 1.0 A g −1 . This superior performance stems from synergistic contributions of abundant redox‐active centers (C═O and C═N groups), which enable efficient Na + storage through multielectron redox mechanisms. This study highlights the strategic advantage of structurally stable COFs with precisely engineered redox‐active motifs via facile synthesis for advancing high‐performance electrochemical energy storage.

Catalytic Polymerization of n‐Doped Poly(benzodifurandione) (n‐PBDF) Using Parts Per Million (ppm) Levels of Molybdenum Trioxide

Abstract The recent discovery of highly conductive, solution‐processable, n‐doped poly(benzodifurandione) (n‐PBDF) has significantly pushed the boundaries of organic electronics. However, to maximize its practical impact, an efficient, scalable and cost‐effective synthetic method is essential. Initially, n‐PBDF was synthesized via duroquinone‐mediated or copper‐catalyzed polymerizations, but these methods required prolonged dialysis, limiting their scalability. Our recent SeO 2 ‐catalyzed polymerization improved efficiency but still necessitated centrifugation and filtration to remove solid selenium byproducts. In this work, we introduce a highly efficient molybdenum trioxide (MoO 3 )‐catalyzed polymerization of n‐PBDF. Remarkably, MoO 3 at parts‐per‐million (ppm) concentrations achieves near‐quantitative monomer conversion (>99% by NMR), eliminating the need for purification. Kinetic studies demonstrate that this polymerization follows a chain‐growth mechanism, enabling the synthesis of high‐quality n‐PBDF polymers with controlled particle sizes and block copolymers. Mechanistic investigations reveal that MoO 3 mediates an oxidative pathway involving dimethyl sulfoxide (DMSO), with dimethyl sulfide (DMS) identified as the reduction product. This innovation not only provides a scalable, low‐cost route to high‐quality n‐PBDF but also unlocks new synthetic opportunities, significantly expanding the synthetic toolbox for functional polymers.

Protective role of Salicylic acid and sodium nitroprusside foliar application against copper stress in okra (Abelmoschus esculentus)

Low‐Coordination Indium Single‐Atom Sites Anchored on a Metal‐Organic Framework Single‐Layer Boosts Electroreduction of CO ₂ Into Formic Acid

Abstract The electroreduction of CO 2 under acidic conditions presents both scientific significance and technical challenges. Herein, we developed a post‐synthetic modification strategy to anchor unexpected tetrahedral In(III) ions onto Zr‐oxo clusters of a single‐layer zirconium metal‐organic framework (denoted as Zr‐MOF‐In ). Operating under harsh acidic conditions (pH = 1.67) at −1.8 V versus RHE, the Zr‐MOF‐In catalyst demonstrates exceptional performance with 95.7% Faradaic efficiency for formic acid production and a current density of 213.3 mA cm −2 . The system maintains operational stability over 20 h without notable activity decay. Remarkably, when integrated into a membrane electrode assembly electrolyzer with solid‐state electrolyte at 4 V full‐cell voltage, Zr‐MOF‐In continuously generates pure formic acid solution (505.5 mmol L −1 , 100% purity) free of electrolyte contamination, achieving a concentration 1.5‐fold higher than the current state‐of‐the‐art. Mechanistic investigations identify dual enhancement mechanisms: i) the low‐coordinated In(III) single‐atom sites facilitate dual *HCOO intermediate binding, enhancing reaction kinetics beyond conventional single‐intermediate adsorption on high‐coordination metal centers; and ii) the single‐layer MOF configuration optimizes active site exposure, synergistically maximizing catalytic efficiency.

The administration of passive and active immunotherapy against Syntenin-1 decreased the tumoral growth and pulmonary metastasis in a murine model of triple-negative breast cancer

Inside Back Cover: Exceptional Second Harmonic Generation in Ultraviolet Nonlinear Optical Oxyfluoroniobate Crystals via Structural Fingerprint Optimization of Polar Chains (Angew. Chem. Int. Ed. 36/2025)

Correspondence of high dimensional emotion structures elicited from video clips between humans and multimodal LLMs

Calix[8]Arene‐Tethered Dendritic Octamer Acceptor with Ultrahigh Molecular Weight Enables 20.7% Efficiency Organic Solar Cells with Exceptional Stability

Abstract Increasing the molecular weight of the acceptor is an effective strategy to suppress excessive crystallization and molecular diffusion, thereby addressing morphological challenges in organic solar cells (OSCs). Therefore, designing high‐molecular‐weight acceptors with well‐defined structures is crucial for achieving efficient and stable OSCs towards commercialization. Herein, we report a calix[8]arene‐tethered dendritic octameric acceptor with a molecular weight of 14243 g mol −1 and a well‐defined structure. Owing to its dendritic structure, which facilitates both multidimensional charge transport and molecular interactions, C8‐IC can operate efficiently, achieving a high‐power conversion efficiency (PCE) of 18.7%, despite its lower crystallinity. Moreover, it effectively acts as a crystallization manipulator, regulating the interaction and crystallization within the D18:L8‐BO system. This optimizes charge management in the ternary system, achieving a state‐of‐the‐art efficiency of 20.7%. To our knowledge, this is among the highest efficiency values reported for OSCs based on dendritic acceptors. Moreover, the ultrahigh molecular weight of the dendritic acceptor effectively increases the glass transition temperature ( T g ), inhibits molecular diffusion, and stabilizes the morphology, leading to significantly improved device stability. This work presents high‐performance OSCs based on a dendritic acceptor with ultrahigh molecular weight and provides valuable insights into the design of acceptor materials for highly stable OSCs.

Prediction of the potential geographic distribution of the Wilsonomyces carpophilus under multiple climate change scenarios

Engineering the Microporous Environment of Flexible Metal–Organic Frameworks with Bifunctionality for Promoting the Separation of Ethylene from a Ternary Mixture

Abstract The separation of ethylene (C 2 H 4 ) from mixtures with carbon dioxide (CO 2 ) and acetylene (C 2 H 2 ) is of great industrial importance but remains a critical challenge. Here, we report that a rationally designed flexible metal–organic framework (FMOF), featuring a specifically engineered microporous environment with bifunctionality, can promote the efficient one‐step separation of C 2 H 4 from a ternary mixture. Adsorption isotherms and dynamic breakthrough tests provide experimental evidence confirming the selective adsorption of CO 2 and C 2 H 2 over C 2 H 4 on such a FMOF, as well as its ability to separate C 2 H 4 from a CO 2 /C 2 H 2 /C 2 H 4 ternary mixture. Theoretical calculations and simulations provide critical insights into the flexible adsorption process and the separation mechanism of the FMOF. The bifunctionality incorporated in FMOF provides exceptionally strong binding of CO 2 and C 2 H 2 but inhibition of C 2 H 4 , which, in turn, enables high adsorption selectivity for CO 2 /C 2 H 4 and C 2 H 2 /C 2 H 4 . This FMOF has high potential for industrial applications in the separation of C 2 H 4 from gas mixtures.

Valorization of novel bifunctional waterborne coatings with UV irradiation resistance and antimicrobial activity

Abstract This research aimed to create bifunctional acrylic waterborne coatings capable of absorbing UV radiation and resisting microbial growth. The compound 4-[2(3-acetylphenyl) diazenyl]-3,5-dimethylphenol (ADD) was incorporated into the waterborne acrylic resin at concentrations of 0.1%, 0.25%, and 0.5%. The coatings underwent characterization through scanning electron microscopy (SEM), mechanical property testing, and the CIELab color method after 500 h of UV exposure to assess their UV shielding effectiveness. Furthermore, the antimicrobial properties of both ADD powder and the coatings were evaluated against Gram-negative bacteria (Helicobacter pylori), Gram-positive bacteria (Staphylococcus aureus), and pathogenic fungi (Candida albicans) using the disc diffusion method. Results indicated that the coatings with 0.25% and 0.5% ADD retained their integrity, showing no cracks or color and texture changes after UV exposure. In contrast, the 0.1% ADD coating exhibited significant alterations in the a* value, revealing its susceptibility to UV damage and limited UV absorption. Positive a* values confirmed the red tint of the films. Antimicrobial activity was notable, with inhibition zones measuring 14 to 26 mm against Staphylococcus aureus, 11 to 21 mm against Helicobacter pylori, and 12 to 20 mm against Candida albicans. Overall, this study demonstrated that the developed coatings with ADD significantly enhance UV absorption and exhibit promising antimicrobial properties, effectively overcoming the limitations of existing commercial coatings and offering a viable solution for protecting surfaces from UV radiation and microbial contamination.

Immune-coagulation dynamics in severe COVID-19 revealed by autoantibody profiling and multi-omics integration

Abstract Severe COVID-19 is characterized by immune-coagulation dysregulation, yet the contribution of related autoantibodies remains poorly understood. We investigated relationships between plasma autoantibody reactivities, whole-blood transcriptomics, plasma proteomics, and clinical laboratory parameters in a cohort of hospitalized COVID-19 patients. Transcriptomic analysis revealed that 42 curated coagulation and complement cascade genes were upregulated in severe cases compared to healthy controls, with 15 genes, including CR1L, ELANE, ITGA2B, ITGB3, VWF, TFPI, PROS1, MMRN1, and SELP (> 1.2 log2 fold-change), also significantly different from mild cases. Autoantibody profiling against eight coagulation-related proteins (ADAMTS13, Factor V, Protein S, SERPINC1, Apo-H, PROC1, Prothrombin, and PF4) showed reactivities below positivity thresholds across all groups. Using an exploratory approach, in severe cases, subthreshold autoantibody candidates (FDR < 0.25) showed negative correlation trends with select gene expressions and inflammatory markers (Factor V with IL-6 and CXCL10), suggesting potential disease-specific immunomodulatory associations. In contrast, while mild cases exhibited stronger gene-protein correlations, they showed limited associations with antigen reactivities or clinical laboratory parameters. Additionally, no correlations were observed between autoantibodies and platelet-counts or Fibrin-D-dimer levels. Age-associated increases in antigen reactivities were noted in severe disease, implying a role for immunosenescence. These findings support further investigation into the role of subthreshold autoantibody candidates in thromboinflammatory COVID-19 pathogenesis.