Browse Articles

Multi-objective operation optimization method of microgrid considering the influence of electric vehicle

Overweight and obesity and its determinants in primary school students: a population-based study from Iran

Decreased PECAM-1 May be a potential pathological factor for vascular injury in T2DM patients

Collocation method for solving fractional reaction–diffusion problem arising in chemistry

Temporal acuity of vision decreases with eccentricity in virtual reality and is associated with schizotypy

Abstract Temporal acuity reflects our ability to consciously detect a perceptual change within a short period of time, such as an asynchrony separating two visual events. In this virtual reality study, fifty participants performed a simultaneity judgment task to estimate temporal acuity across the visual field and filled the schizotypal personality questionnaire. Topographic maps were computed to visualize asynchrony discrimination skills across the visual space in two different (natural and artificial) static virtual environments. We investigate visual temporal acuity in periphery, and how estimates of temporal acuity in a psychophysical-like setting translates into a naturalistic-like scenario. First, the temporal acuity of vision decreases as the eccentricity of the targets increases, but it remains constant across meridians. Second, this deterioration of temporal coding in peripheral vision concerns non-medicated individuals self-reporting perceptual and cognitive schizotypal traits. Third, temporal acuity estimated in a traditional psychophysical visual context does not generalize to an ecologically-valid landscape scenery, such that asynchrony discrimination skills are reduced under natural vision conditions. The results suggest that distinct temporal mechanisms drive visual temporal acuity in central and peripheral vision. Furthermore, perceptual and cognitive disturbances in the neurotypical population may be linked to abnormal temporal processing in peripheral vision. Overall, these findings may pave the way toward novel investigations into the variety of time experiences across neurotypical and neurodivergent populations.

Secondhand smoke is associated with abdominal obesity and high obesity index in a large Taiwanese population study

Biochar modification enhances mechanical and durability properties of cement-based materials

Emotion and sentiment enriched decision transformer for personalized recommendations

A distinct class of ferredoxin:NADP+ oxidoreductase enzymes driving thermophilic ethanol production

Integration of multiple coinflip devices for high-quality random sampling

Full process evolution of deformation and seepage coupling in fractured rock under triaxial stress

Short term prediction of photovoltaic power with time embedding temporal convolutional networks

Aberrant static and dynamic functional connectivity of insular cortex in patients with trigeminal neuralgia

Study on artificial reinforced concrete roof’s thickness for subsequent backfilling method in fragmented rock mass deposits

Development and characterisation of brown seaweed hydrolysates and fermentates with potential to reduce enteric methane

Mechanical properties and acoustic emission activity characteristics of different coal-rock ratios under uniaxial cyclic loading

Experimental study of the effect of natural fracture curvature on hydraulic fracture propagation behavior

Machine learning based prediction modeling of micro-EDM of Ti–29Nb–13Ta–4.6Zr (TNTZ)

Calcium triggers calmodulin degradation to induce EGF receptor instability and overcome non-small cell lung cancer resistance to tyrosine kinase inhibitors

Computational insights and study of drugs for dry eye disease through QSPR and MCDM approaches using topological indices

Abstract Sjögren’s syndrome is a cause of dry eye disease (DED) which leads to discomfort due to the lack of tear in the eye. This study aims at computing various topological indices for the molecular graphs of dry eye disease drugs. Multiple linear regression is applied to validate the relation between seven physicochemical properties and 11 topological indices. QSPR analysis is carried out for topological indices having correlation greater than 0.82 with properties polar surface area, polarizability, boiling point, enthalpy, molar refraction, molar volume, molecular weight and complexity. Furthermore, the multiple-criteria-decision-making (MCDM) techniques TOPSIS, and VIKOR are used to rank the drugs. For the considered properties of drugs under the study, polarizability has shown significant results with high correlation and least RMSE (r = 0.996 & RMSE = 1.419). The analysis revealed that Tacrolimus and Cyclosporine being ranked number 1 and number 22 respectively as identified by TOPSIS and VIKOR.