Browse Articles

Receptor activity–modifying protein 3 enhances GLP-1-mediated insulin secretion

Journal of Biological Chemistry Abigail Pearce, Poonam Kumari, Claudia M. Sisk et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110604

Targeting DNA damage in ageing: towards supercharging DNA repair

Nature Reviews Drug Discovery Arturo Bujarrabal-Dueso, George A. Garinis, Paul D. Robbins et al. Oct 01, 2025 DOI: 10.1038/s41573-025-01212-6

Evolution of drug-resistant ovarian-cancer clones tracked in patients

Nature Oct 01, 2025 DOI: 10.1038/d41586-025-03163-9

Identification of ALKBH6 as a nucleotide demethylase with a distinct substrate preference

Journal of Biological Chemistry Susmita Das, Sourbh Rankawat, Unnikrishnan P. Shaji et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110638

Impact of Hot Carrier Dynamics on Photoelectrocatalytic Activity on Au@Pd Antenna-Reactor Nanoparticles

Journal of the American Chemical Society Hyewon Park, Seunghyun Chun, Jeong Hoon Lee et al. Oct 01, 2025 DOI: 10.1021/jacs.5c12825

10 things you wish you knew about inflammatory caspases: A holistic review of their biochemistry, activation, and signalling

Journal of Biological Chemistry Sebastian Grant, Dave Boucher Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110557

Stable Isotope Labeling of Pyrimidines Using a Deconstruction–Reconstruction Strategy

Journal of the American Chemical Society Benjamin J. H. Uhlenbruck, Andrew McNally Oct 01, 2025 DOI: 10.1021/jacs.5c09719

A comparative analysis reveals electrogenic properties of PfCRT and pendrin

Journal of Biological Chemistry Eva Gil-Iturbe, Matthias Quick Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110630

In situ metabolomics reveals intra-islet metabolite changes upon in vivo stimulation of insulin secretion

Journal of Biological Chemistry Yan Zhou, Nicolas Baez, Tingting Fu et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110661

Late-Stage Tryptophan Modification of Native Peptides through Photochemical Indole-to-Quinazoline Editing

Journal of the American Chemical Society Heng-Hui Li, Yisa Xiao, Han Liu et al. Oct 01, 2025 DOI: 10.1021/jacs.5c12511

Targeting protein disorder: the next hurdle in drug discovery

Nature Reviews Drug Discovery Tamas Lazar, Acadia Connor, Charles F. DeLisle et al. Oct 01, 2025 DOI: 10.1038/s41573-025-01220-6

Machine learning matches enzymes with molecular substrates

Nature Oct 01, 2025 DOI: 10.1038/d41586-025-03161-x

Suppression of SREBP by a transmembrane protein mutated in cardiomyopathy

Journal of Biological Chemistry Yasushi Takemoto, Manchir Tserendagva, Motonari Uesugi Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110644

Local Electric Fields Originate Unusual Kinetic Isotope Effects in the Hydrogen Abstraction Reactions of the Functionally Analogous P450 and TauD Enzymes

Journal of the American Chemical Society Surajit Kalita, David Danovich, Sason Shaik Oct 01, 2025 DOI: 10.1021/jacs.5c10488

The activity of the EMT suppressor GRHL2 is regulated by SUMOylation

Journal of Biological Chemistry Sonja Santjer, Yang Xu, Sabine Riethdorf et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110662

Coherent Control over Nuclear Hyperpolarization Using an Optically Initializable Chromophore-Radical System

Journal of the American Chemical Society Hoang M. Le, Joshua S. Straub, Quentin Stern et al. Oct 01, 2025 DOI: 10.1021/jacs.5c07862

Functional dissection of the zDHHC palmitoyltransferase 5–golgin A7 palmitoylation complex

Journal of Biological Chemistry Martha A. Kahlson, Joan Ritho, João Victor Gomes et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110694

Tightly yet Dynamically Bound Aliphatic Guanidinium Ligands for Lead Halide Perovskite Nanocrystals

Journal of the American Chemical Society Yuliia Berezovska, Sebastian Sabisch, Caterina Bernasconi et al. Oct 01, 2025 DOI: 10.1021/jacs.5c09354

Hydrogen sulfide–dependent activation of human sulfide quinone oxidoreductase

Journal of Biological Chemistry Joseph V. Roman, Yashvi Shukla, David A. Hanna et al. Oct 01, 2025 DOI: 10.1016/j.jbc.2025.110681

Spinel/Rock Salt Core/Shell High-Entropy Oxides for Selective CO₂ Hydrogenation

Journal of the American Chemical Society Ke Wang, Wooseok Lee, Rui Zhang et al. Oct 01, 2025 DOI: 10.1021/jacs.5c07731