Browse Articles

Discover research articles across all indexed journals

Hydroxytyrosol ameliorates imiquimod-induced psoriasis-like dermatitis by modulating ERK and NF-κB signaling pathways in mice

Scientific Reports Meng Liu, Ruihan Fan, Li Chen et al. Aug 17, 2025 DOI: 10.1038/s41598-025-16198-9

Comparing the effect of pre-anesthesia clonidine and tranexamic acid on intraoperative bleeding volume in rhinoplasty: a machine learning approach

Scientific Reports Zahra Asghari Varzaneh, Akram Hemmatipour, Hadi Kazemi-Arpanahi Aug 17, 2025 DOI: 10.1038/s41598-025-07450-3

Relationships between burnout and coping strategies among assistant medical officers in Malaysian public healthcare facilities

Scientific Reports Nor Haniza Zakaria, Nursyahda Zakaria, Kun Yun Lee Aug 17, 2025 DOI: 10.1038/s41598-025-14036-6

Vegetation variations and driving mechanisms in northern China based on kNDVI

Scientific Reports Zhuxia Xu, Weicheng Liu, Haiyan Li et al. Aug 17, 2025 DOI: 10.1038/s41598-025-14232-4

Mycobiome of low maintenance iconic landscape plant boxwood under repeated treatments of contact and systemic fungicides

Scientific Reports Xiaoping Li, Ginger Hemmings, Olanike Omolehin et al. Aug 17, 2025 DOI: 10.1038/s41598-025-07593-3

Determination of disintegration time using formulation data for solid dosage oral formulations via advanced machine learning integrated optimizer models

Scientific Reports Mohammed Ghazwani, Umme Hani Aug 17, 2025 DOI: 10.1038/s41598-025-15996-5

Comparative study of ontogenetic trophic transition in large yellow croaker from Hong Kong and Taiwan using metabarcoding and isotope analysis

Scientific Reports Hei-Ching Wong, Chun-Ming How, Leyi Xi et al. Aug 17, 2025 DOI: 10.1038/s41598-025-15014-8

Transcriptionally up-regulation of CDKN1A/p21 by TFE3 fusion proteins worsened TFE3-rearranged renal cell carcinoma

Scientific Reports Yanwen Lu, Wenliang Ma, Yi Chen et al. Aug 17, 2025 DOI: 10.1038/s41598-025-13302-x

Reliability of the single leg stance test for safe removal of external fixator after tibial bone lengthening

Scientific Reports Mahmoud El-Rosasy, Osama Elgebaly, Amr Elrosasy et al. Aug 17, 2025 DOI: 10.1038/s41598-025-14584-x

Abstract The timing of fixator removal in distraction osteogenesis is an important decision. Bipedal weight bearing may not be an accurate estimate of body weight distribution on both limbs. The purpose of this study was to test the reliability of the Single leg stance test (SLST) as an indicator of regenerate bone maturation and safe removal of the external fixator. Patients who underwent Ilizarov limb reconstruction for tibial bone lengthening were classified into two groups. The decision to remove the external fixator was based on radiological analysis and Bipedal walking in group A versus SLST in Group B. to be included in the study, the patient should be able to communicate, perform the test on the healthy limb, have no neuromuscular, visual or vestibular disorders, can do bipedal weight bearing unsupported and plain radiographs show at least three intact cortices. The data was collected retrospectively from 2012 to 2015 in group A and prospectively from 2016 to 2022 in group B. Interpretation of the test was done by two experienced surgeons in limb reconstruction and a junior orthopedic surgeon. A total of 50 patients and 52 patients were included in group A and B respectively. The inter-observer reliability of the three observers was almost perfect. Refracture after external fixator removal occurred in five cases in group A (10%) and one case in group B (1.9%). The SLST was able to predict regenerate maturation in 98% of cases in our series.The SLST is a simple, reproducible, and reliable clinical test that can be used to evaluate the maturation of the regenerate.

Exploring behavior of Clinoptilolite@Graphene oxide compositeas a novel adsorbent for CO2 capture

Scientific Reports Maryam Helmi, Ahad Ghaemi, Mohammad Amin Sobati Aug 17, 2025 DOI: 10.1038/s41598-025-15204-4

Discrete event simulation and agent-based modelling of distributed situation awareness in patient flow management

Scientific Reports Abdulrahman A. Alhaider, Nathan Lau, Osama Alotaik et al. Aug 17, 2025 DOI: 10.1038/s41598-025-15344-7

Network pharmacology and metabolomics reveal mathurameha, a Thai traditional Anti-Diabetic formula, enhances glucose metabolism through PI3K-AKT/AMPK/GLUT4 pathway modulation

Scientific Reports Subhadip Banerjee, Wuttichai Jaidee, Narawadee Rujanapun et al. Aug 17, 2025 DOI: 10.1038/s41598-025-15556-x

Imaging characteristics of renal epithelioid angiomyolipoma and its correlation with risk stratification

Scientific Reports Jin Zhou, Guo-chu Qin, Ting-ting Chen et al. Aug 17, 2025 DOI: 10.1038/s41598-025-15340-x

An efficient and interactive feature selection approach based on copula entropy for high-dimensional genetic data

Scientific Reports Xiaoran Yan, Shilong Shang, Dongxi Li et al. Aug 17, 2025 DOI: 10.1038/s41598-025-15068-8

Computational analysis of entropy generation in EMHD micropolar dusty fluid flow incorporating esterification process

Scientific Reports Aziz Ullah Awan, Muzammil Hussain, Bagh Ali et al. Aug 17, 2025 DOI: 10.1038/s41598-025-15017-5

SCSFish2025: a large dataset from South China sea for coral reef fish identification

Scientific Reports Meng Wang, Wei Xiao, Ying Wang et al. Aug 17, 2025 DOI: 10.1038/s41598-025-14785-4

Research on the improvement of daily living skills of children with autism in virtual campus environments

Scientific Reports Li Li, Xiao Zhu, Sixuan Wan et al. Aug 17, 2025 DOI: 10.1038/s41598-025-08224-7

Causal association between employment transitions and suicide in Australia

Scientific Reports Swikar Poudel, Sandro Sperandei, Andrew Page et al. Aug 17, 2025 DOI: 10.1038/s41598-025-14217-3

Abstract Suicide remains a significant public health concern globally, with unemployment, financial hardship, and employment transitions cited as contributing factors. However, their causal association remains unclear. This study investigates the causal association between employment transitions and suicide in Australia from 2009 to 2018, utilising Convergent Cross Mapping (CCM), a dynamical systems approach. Employment transitions were categorised into positive transition, no transition, and negative transition groups, representing changes in employment status. Initial analysis of raw data suggested all three groups showed causal association to suicide. However, detrending the time series revealed that only negative transition maintained a significant causal association with suicide, while no transition and positive transition showed no causal association. These findings emphasise the critical association of employment instability on mental health and the importance of stable or improving employment conditions in suicide prevention. The study discusses the need for targeted interventions to mitigate the adverse effects of employment downturns.

A novel solid phase synthesis of an estradiol derivative and preclinical evaluation for targeting estrogen-receptor positive breast cancer

Scientific Reports Subhani M. Okarvi Aug 17, 2025 DOI: 10.1038/s41598-025-15367-0

Study of thermal performance and melting behaviour of a novel paraffin wax-carbon quantum Dots PCMs

Scientific Reports G. Murali, J. Emeema, B. Venkateswara Reddi et al. Aug 17, 2025 DOI: 10.1038/s41598-025-08312-8