Browse Articles

Correction: Arg-73 of the RNA endonuclease MazF in Salmonella enterica subsp. arizonae contributes to guanine and uracil recognition in the cleavage sequence

Journal of Biological Chemistry Takuma Okabe, Rie Aoi, Akiko Yokota et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110767

Cancer cachexia contender enters first pivotal trial

Nature Reviews Drug Discovery Asher Mullard Nov 01, 2025 DOI: 10.1038/d41573-025-00168-x

Missense mutations in intrinsically disordered protein regions link pathogenicity and phase separation

Journal of Biological Chemistry Oliver L. Kipp, Karen A. Lewis, Loren E. Hough et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110773

Roche buys MASH contender for up to US$3.5 billion

Nature Reviews Drug Discovery Asher Mullard Nov 01, 2025 DOI: 10.1038/d41573-025-00167-y

New insights into the crosstalk between endocannabinoids and sphingosine-1-phosphate

Journal of Biological Chemistry Cinzia Rapino, Sara Standoli, Francesca Cencetti et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110781

FDA approves BTK inhibitor for chronic hives

Nature Reviews Drug Discovery Asher Mullard Nov 01, 2025 DOI: 10.1038/d41573-025-00165-0

New biochemical approaches for the treatment of glioblastoma

Journal of Biological Chemistry Laura A. Lindsey-Boltz, Aziz Sancar Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110748

Genmab nabs EGFR × LGR5 bispecific in US$8 billion Merus acquisition

Nature Reviews Drug Discovery Asher Mullard Nov 01, 2025 DOI: 10.1038/d41573-025-00166-z

G-Quadruplex–specific action of chloroquine-based immunomodulator drugs to inhibit the cancer progression

Journal of Biological Chemistry Sunipa Sarkar, Akash Chatterjee, Subhojit Paul et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110753

Designer peptide retunes channel function

Nature Reviews Drug Discovery Katie Kingwell Nov 01, 2025 DOI: 10.1038/d41573-025-00163-2

Identification of a novel GREMLIN1 uptake pathway in epithelial cells that requires BMP binding

Journal of Biological Chemistry Zhichun Gao, Yuhan Gao, Louise R. Dutton et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110780

Macrocyclic peptides challenge cell cycle defects

Nature Reviews Drug Discovery M. Teresa Villanueva Nov 01, 2025 DOI: 10.1038/d41573-025-00162-3

BATF2-mediated control of astrocyte proliferation

Journal of Biological Chemistry Rachel A. Tinkey, Benjamin J. Frostino, Maria L. Habean et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110710

Rebalancing cardiolipin biosynthesis to treat cardiomyopathy

Nature Reviews Drug Discovery Alex Eccleston Nov 01, 2025 DOI: 10.1038/d41573-025-00161-4

The necessity of multi-parameter normalization in cyanobacterial research: A case study of the PsbU in Synechocystis sp. PCC 6803 using CRISPRi

Journal of Biological Chemistry Maria Christine Veit, Ron Stauder, Yu Bai et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110763

Targeting GPR31 to treat MASH

Nature Reviews Drug Discovery Sarah Crunkhorn Nov 01, 2025 DOI: 10.1038/d41573-025-00158-z

An amino acid transporter in the small intestine mediates basolateral efflux of plant-derived nicotianamine iron complexes

Journal of Biological Chemistry Yoshiko Murata, Makoto Fujisawa, Takehiro Watanabe et al. Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110731

Blocking SLC38A2 lowers blood pressure

Nature Reviews Drug Discovery Sarah Crunkhorn Nov 01, 2025 DOI: 10.1038/d41573-025-00157-0

Omics characteristics and epigenetic modifications of adipose-derived stem cells

Journal of Biological Chemistry Tiange Feng, Clifford J. Rosen, Ziru Li Nov 01, 2025 DOI: 10.1016/j.jbc.2025.110758

A degrader of oncoprotein SKP2

Nature Reviews Drug Discovery Sarah Crunkhorn Nov 01, 2025 DOI: 10.1038/d41573-025-00159-y