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Involvement of LncRNA FAF in chemotherapy-induced cardiotoxicity by mediating pyroptosis through modulation of the NLRP3-Caspase-1 signaling pathway

Scientific Reports Ziyu Feng, Jinhui Sun, Qiang Geng et al. Dec 12, 2025 DOI: 10.1038/s41598-025-31983-2

Effectiveness of rehabilitation dose heterogeneity for improving functional outcomes of patients with acute stroke: a nationwide observational study

Scientific Reports Takuaki Tani, Masashi Kanai, Masatoshi Kamada et al. Dec 12, 2025 DOI: 10.1038/s41598-025-32006-w

A MAGDM approach based on dual hesitant Q-rung orthopair fuzzy Dombi norm with Hamy mean operators and its application

Scientific Reports Xiuqin Ma, Mengyao Wang, Hongwu Qin et al. Dec 12, 2025 DOI: 10.1038/s41598-025-30997-0

Thixo-viscoelastoplastic rheological characterisation of human mucus using a multimode BMP constitutive equation approach

Scientific Reports Michelle Figueroa-Landeta, Sarahí L. Esponda-Cervantes, M. Fernanda Reyes-Tenorio et al. Dec 12, 2025 DOI: 10.1038/s41598-025-16178-z

Binding modes and interaction mechanism of bisphenol A and its analogs in constitutive androstane receptor

Scientific Reports Manikandan Jayaraman, Vijayakumar Gosu, Maharaja Muthuvairam Subbulakshmi et al. Dec 12, 2025 DOI: 10.1038/s41598-025-30642-w

Topological interface state-based photonic crystal sensor with porous cap layer for high-performance biosensing

Scientific Reports Jamal Barvestani Dec 12, 2025 DOI: 10.1038/s41598-025-27526-4

Optogenetic regulation of chloride ions in reactive astrocytes may mitigate Parkinson’s disease pathology

Scientific Reports Eun Jung Lee, Hyung Ho Yoon, Sang Ryong Jeon Dec 12, 2025 DOI: 10.1038/s41598-025-30935-0

Numerical study on small hole leakage and diffusion of hydrogen in buried pipelines

Scientific Reports Longfei Dong, Xin Pang, Rui Zhang Dec 12, 2025 DOI: 10.1038/s41598-025-27422-x

Impact of SAAC accreditation on laboratories in Saudi Arabia according to ISO/IEC 17025:2017

Scientific Reports Amar Alomair, Mohammed Alfayez, Muaath Abuhaimed et al. Dec 12, 2025 DOI: 10.1038/s41598-025-30089-z

Land use and land cover changes drive ecosystem services value in the Chinese county of Qianyang

Scientific Reports Wang Shuangao, Pedro Cabral, Yuefeng Xu et al. Dec 12, 2025 DOI: 10.1038/s41598-025-29320-8

Abstract Understanding how land use changes affect ecosystem services is essential for guiding sustainable development and environmental policy. In rapidly urbanizing regions, quantifying these impacts helps inform land management decisions. This study aims to analyze the impact of land use and land cover (LULC) changes on Ecosystem Services Value (ESV) in Qianyang County, China. We utilized land use data from 2007 to 2022 with a spatial resolution of 30 m. The spatial distribution and clustering of ESV were examined using spatial statistical methods. The Patch-generating Land Use Simulation (PLUS) model, which simulates LULC changes under three scenarios for 2050, was employed to calculate ESV and identify driving forces. Results show that urbanization and topography were the main driving factors for LULC changes in Qianyang County. Our findings provide valuable insights into sustainable land management and ecosystem conservation in the region.

Soil organic carbon fractions and their associated bacterial and fungal abundance in alpine ecosystems

Scientific Reports Ilaria Fracasso, Lizzie Foley, Raphael Tiziani et al. Dec 12, 2025 DOI: 10.1038/s41598-025-31187-8

Introducing an efficient method for feature extraction in image retrieval systems

Scientific Reports Xiaojun Zhao, Feng He, Kun Li Dec 12, 2025 DOI: 10.1038/s41598-025-24118-0

Structural model of hard overburden shell in thick coal seam and its application

Scientific Reports Xing Fu, Lingjun Zeng, Hai Rong et al. Dec 12, 2025 DOI: 10.1038/s41598-025-32117-4

Pharmacological activation of SERCA2 reverses ER calcium dysregulation and depression-like behaviors in hyperglycemic mice

Scientific Reports Huiju Lee, Yiseul Han, Ju-Yeon Song et al. Dec 12, 2025 DOI: 10.1038/s41598-025-31293-7

A unified multi-task learning framework for automated assessment of left ventricular structure and its systolic function from echocardiography

Scientific Reports Zeinab Khodaverdian, Ehsan Kozegar, Hossein Sadr et al. Dec 12, 2025 DOI: 10.1038/s41598-025-31773-w

Network pharmacology and molecular docking reveal antiviral mechanisms of silver nanoparticles synthesized by Oscillatoria sp. against HCV pathogenesis

Scientific Reports Lamya Azmy, Ebtesam Al-Olayan, Mohamed A. A. Abdelhamid et al. Dec 12, 2025 DOI: 10.1038/s41598-025-26310-8

Automated skin cancer detection using MedFusionNet with attention-based fusion of ConvNeXt and vision transformer

Scientific Reports Muhammad Ahtsam Naeem, Shangming Yang, Muhammad Asim Saleem et al. Dec 12, 2025 DOI: 10.1038/s41598-025-31816-2

Abstract Skin cancer, especially melanoma, the most severe type, has increased in recent decades. It develops from cells that grow abnormally and can invade the surrounding tissue and spread throughout the body. Early and accurate diagnosis is essential to prevent disease progression and allow for less invasive clinical treatment. The extraction of complex dermoscopic images and the improvement of lesion classification performance have significantly improved skin cancer diagnosis through the use of convolutional neural networks (CNNs). In this study, a novel deep convolutional neural network that combines ConvNeXt and Vision Transformer (ViT) architectures through an adaptive attention-based approach for advanced feature fusion to automatically multi-classify skin cancer samples. This model is evaluated on two dermoscopy benchmark datasets, including ISIC-2019 and HAM10000 and both datasets reflect the real-world problem of class imbalance. The evaluation results of MedFusionNet are calculated using various evaluation metrics, including accuracy, precision, recall and AUC and compared with deep learning algorithms such as ResNet50, MobileNet V2, DenseNet121 and ViT-B16. The experimental results show that MedFusionNet outperforms the current models with a classification accuracy of 98.80% and 97.90% for HAM10000 and ISIC-2019, respectively. Grad-CAM visualizations qualitatively show that the model focuses on clinically relevant lesion regions, providing interpretive insight without claiming complete causal explainability. The results show that the proposed model can efficiently handle multi-class tasks in dermatological imaging and MedFusionNet is a suitable choice for implementation in real-world computer-aided diagnosis systems.

Effect of posture on photoplethysmography signals from the posterior tibial artery in adults with and without type 2 diabetes

Scientific Reports Apakrita Tayade, Saurav Kumar, Amber Shrivastava et al. Dec 12, 2025 DOI: 10.1038/s41598-025-28223-y

Predicting biological sex in pediatric skeleton X-rays using artificial intelligence

Scientific Reports Michael Janisch, Mario Scherkl, Nikolaus Stranger et al. Dec 12, 2025 DOI: 10.1038/s41598-025-28197-x

A novel cryptographic framework and mathematical modeling for secure transmission of Parkinson’s disease data using RSA and block-based secret sharing

Scientific Reports Thalapathiraj Sambandham, Hari Mohan Srivastava, Stalin Thangamani et al. Dec 12, 2025 DOI: 10.1038/s41598-025-32227-z