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New design of a high-efficiency rectenna for wireless power transfer in 5G applications
Multi-objective optimization of a regional biogas supply chain using organic waste
Exploring the new classes of optical soliton solutions with diverse structure for the (2+1)–dimensional paraxial equation in fiber optics via two analytical methods
Integrated multi-omics analysis identifies and validates endoplasmic reticulum stress and mitophagy-related biomarkers in MASLD
Deep learning-enhanced shoreline dynamics and vulnerability assessment in Niger Delta area of Nigeria
Profiling extracellular matrix-driven heterogeneity of single cell migration and morphology
Narrower jugular bulbs and their tributaries are associated with skull base venous hyperintensity on arterial spin-labeling MRI
Abstract Incidental arterial spin-labeling MRI hyperintensity (ASL+) at the jugular bulb (JB) can mimic dural arteriovenous fistula but its anatomical basis remains incompletely understood. We investigated whether JB and tributary sizes are associated with ASL+. We retrospectively analyzed MRIs from 25 ASL+ patients and 25 controls, using post-contrast SPGR images to measure JB and tributary diameters. Group comparisons, effect sizes, false discovery rate (FDR) correction, and receiver operating characteristic (ROC) analyses were performed, with leave-one-out cross-validation (LOOCV) to assess model stability. ASL+ patients demonstrated smaller JB midportion ( P = 0.047, Cohen’s d = 0.58), JB outflow ( P = 0.030, d = 0.63), and posterior condylar vein (PCV) diameters ( P = 0.009, d = 1.02). After FDR correction across eight comparisons, only PCV remained statistically significant. ROC analysis demonstrated moderate discrimination for JB measures (AUC ≈ 0.67) and stronger discrimination for PCV (AUC = 0.78). A multivariate model achieved AUC = 0.83 with stable LOOCV performance (AUC = 0.77), suggesting limited overfitting. Thus, we identify a venous morphometric pattern associated with ASL+, characterized by smaller JB and PCV calibers. However, given multiplicity adjustment and spatial-resolution constraints for PCVs, these associations should be interpreted as exploratory. This composite anatomical configuration may contribute to delayed venous transit and ASL signal trapping, providing a plausible structural contributor to this imaging pitfall and informing future mechanistic investigations.
Analysis of rainfall response and graded warning for landslides
VALORIS: One-shot and lossless vertical logistic regression for privacy-protecting multi-site health analytics
Abstract Health analytics increasingly relies on variables held by different entities, such as clinical, laboratory, environmental, and genomic data. Due to legal, ethical, and social acceptability constraints, these vertically partitioned data often cannot be shared across organizations holding them. Conducting statistical analyses in such settings requires methods that protect privacy. We introduce VALORIS (Vertically partitioned Analytics under the LOgistic Regression model for Inference in Statistics), a novel method that enables lossless statistical inference (equivalent to the pooled analyses) under a logistic regression model without disclosing any individual-level data–including the outcome variable. VALORIS is a practical, one-shot algorithm that requires no third-party coordinator. The privacy-preserving properties of VALORIS were mathematically assessed, and a privacy-aware setting-dependent framework was provided to ensure individual-data privacy. We demonstrate the accuracy and feasibility of VALORIS through the investigation of potential factors associated with kidney failure among pediatric patients with chronic kidney disease using real health data from Necker-Enfants Malades Hospital. We further validate the proposed algorithm on a larger scale with a reproducible application using the MIMIC-IV database.
Effects of early inertial exercises on morphological and functional recovery after ACL reconstruction
Abstract Effective and safe rehabilitation following ACL reconstruction is an important factor in determining a patient’s return to health. This pilot randomized controlled trial aimed to compare the effectiveness of two rehabilitation protocols in patients following ACL reconstruction. Twenty-four adults following anterior cruciate ligament reconstruction were randomly allocated to the study groups. The first group (SR) underwent standard rehabilitation, whereas the experimental group (SRI) performed standard rehabilitation and additional inertial exercises starting from the seventh week. After 12 weeks of rehabilitation, isokinetic and inertial strength, dynamic balance, thigh circumference, and body composition were evaluated. At the post-intervention assessment, both groups demonstrated comparable isokinetic strength and dynamic balance performance, with no significant between-group differences. In contrast, the SRI group demonstrated greater restoration of morphological symmetry and interlimb strength symmetry under inertial loading compared with the SR group ( p < 0.05; Cohen’s d = 1.37). Additionally, only the SRI group exhibited a significant increase in muscle mass of the operated limb, whereas no significant change was observed in the SR group. These findings indicate that early inclusion of inertial training provides additional benefits in morphological and inertial interlimb symmetry, without compromising conventional neuromuscular strength or balance outcomes following arthroscopic ACL reconstruction.