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Associations between tattooed body surface area and maladaptive personality traits in a community sample
Abstract Evidence for personality differences between tattooed and non-tattooed adults is mixed. Assessing dimensional maladaptive traits may help clarify these associations. A community sample of adults in Cyprus ( N = 280; M = 28.0, SD = 9.5; range 18 to 64) completed the Personality Inventory for DSM-5 Brief Form Adult (PID-5-BF) and a Tattoo Coverage Tool estimating the percentage of body surface area tattooed (tBSA). Analyses included t-tests, correlations, and hierarchical regressions controlling for age, sex, and socioeconomic status. More than half (58.6%) of the participants reported having at least one tattoo. Compared with non-tattooed participants, tattooed participants scored higher on Disinhibition ( d = 0.47, p < .01) and on the PID-5-BF total ( d = 0.29, p = .02). tBSA correlated with Antagonism ( r = .26, p < .01), Disinhibition ( r = .21, p < .01), and the PID-5-BF total ( r = .16, p = .01). Tattoo count showed weaker associations (Disinhibition r = .14, p < .05; Psychoticism r = .12, p < .05). In regressions, Antagonism alone explained 6.8% of the variance in tBSA ( p < .001) and Disinhibition alone explained 4.6% ( p < .001). In the joint model, Antagonism and Disinhibition explained 7.7% of the variance in tBSA ( p < .001), with Antagonism emerging as a significant predictor ( p < .01). Men reported higher tBSA and higher Antagonism, Detachment, Disinhibition, Psychoticism, and PID-5-BF total scores; women scored higher on Negative Affectivity. Tattoo presence was associated with higher Disinhibition and a higher overall maladaptive trait load, while Antagonism best tracked tBSA. tBSA was more sensitive than counts for detecting trait associations. Findings support AMPD-aligned assessment and the use of tBSA in community research on tattooing.
Delamination of lithium iron phosphate from aluminum foil using electrical pulsed discharge without heat, water, or chemicals
AI-driven dynamic resource allocation for ISAC systems in 6G networks: intelligent beamforming, interference management, and power allocation
Multi-dimensional attention transformer for vehicle and pedestrian detection in adverse weather
RAS/BRAF wild-type metastatic high-methylated colorectal cancer has gene expression patterns related to MSI-H and BRAF V600E mutant: a translational research
Bioaccumulation of toxic and essential elements and enzymatic responses in native fish from the middle Tocantins River
Abstract This study provides the first ecotoxicological evaluation of potentially toxic elements (PTEs), essential elements (EEs), and enzymatic biomarkers in two native fish species, Branquinha ( Psectrogaster amazonica ) and Branquinha-cascuda ( Caenotropus labyrhinthicus ), from the middle Tocantins River, Brazil. Specimens were collected from the urban riverside zone of Beira Rio (P1) and a fluvial beach near the rural community of Embiral (P2). PTEs and EEs concentrations were measured in liver and muscle tissues, and biochemical biomarkers included acetylcholinesterase (AChE), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP). Human health risks associated with fish consumption were assessed using the bioconcentration factor (BCF), risk quotient (RQ), and estimated daily intake (EDI). In P. amazonica (urban zone), arsenic (As) exceeded limits by 83–266% in muscle and 60–220% in liver, lead (Pb) in liver by 95–1850%, and selenium (Se) by up to 4537%. In C. labyrhinthicus (rural zone), As and Se in muscle exceeded limits by 185–470% and 5–200%, respectively, while Pb and zinc (Zn) were not detected. BCF values indicated moderate bioaccumulation of sulfur (S) (2867.29) and iron (Fe) (2641.30). Risk assessment revealed a high level of concern, with an RQ for Se reaching 53.13 and As intake exceeding child safety thresholds sevenfold, highlighting significant food safety risks.
Microbiome signatures of mangroves and salt marsh halophyte rhizosphere soil sediments: a metagenomic approach
Kerogen-rich rocks influence growth and composition of an anaerobic microbial community
Abstract Kerogen, insoluble macromolecular organic matter in sedimentary rocks, is the most abundant form of organic carbon on Earth and plays a role in deep biosphere processes. It is classified into four types (I–IV) based on origin and chemical composition, yet its influence on microbial communities and carbon cycling remains poorly understood. In this study, we examined how kerogen-rich shales and coals, each containing a distinct kerogen type, shape anaerobic microbial community development and activity. CFU counts showed that kerogen types I and II did not significantly alter overall microbial abundance, while type III-rich rocks inhibited growth, and type IV-rich rocks enhanced it. 16S rRNA gene sequencing revealed that type II-rich rocks selectively enriched for Burkholderiaceae, whereas type IV-rich rocks promoted the proliferation of Cellulomonadaceae and Pleomorphomonadaceae. Gas chromatography showed that CO 2 production occurred only in the presence of type II-rich rocks, likely driven by Burkholderiaceae activity. These findings suggest that kerogen structure and geochemical properties drive microbial community assembly and organic matter mobilization in the deep subsurface. Beyond Earth, kerogen type IV-like material is widespread in extraterrestrial environments. Our results indicate the enhancement of the habitability of these environments, offering new insights into the potential for life.
Occurrence of Nigrospora spp. as the predominant causal agents of leaf spot disease in Cavendish banana in banana plantations in Mindanao Island, Philippines
A comprehensive cancer analysis investigating the oncogenic role of zinc finger protein 36 (ZFP36) in human tumors
Abstract The RNA-binding protein ZFP36 is involved in tumorigenesis. To systematically elucidate its pan-cancer role, we conducted an integrated analysis of ZFP36 across malignancies, combining bioinformatic exploration with experimental validation. Utilizing datasets from TCGA, GEO, GTEx, HPA, CPTAC, GEPIA2, TIMER2, cBioPortal, and STRING, we employed bioinformatics methods to investigate the potential carcinogenic properties of ZFP36 . This included examining correlations between ZFP36 and gene expression, prognosis, gene mutation, immunohistochemistry staining, immune cell infiltration, and constructing an interaction network of 50 ZFP36 -binding proteins. Additionally, we performed enrichment analysis of ZFP36 -related partners. Furthermore, to validate key bioinformatic predictions, quantitative real-time PCR (qRT-PCR) was performed on paired cancer/normal cell lines (LIHC, LUAD, BRCA). ZFP36 expression was found to be dysregulated in a cancer type-dependent manner, with significant upregulation observed in most tumor types analyzed, including BLCA, BRCA, LIHC, and LUAD. Furthermore, ZFP36 demonstrated early diagnostic value across 33 types of tumors and showed varying associations with prognosis depending on the tumor type. ZFP36 was also significantly associated with most immune-infiltrating cells in pan-cancer analyses. High ZFP36 expression was linked to pathways related to tumor progression. Critically, these bioinformatic predictions were experimentally validated, as qRT-PCR confirmed the significant upregulation of ZFP36 and its functional network genes ( SOCS3 , JUN , SLC7A11 , CSRNP1 ) in LIHC, LUAD, and BRCA cell lines. This study provides a comprehensive pan-cancer analysis of ZFP36 , integrating bioinformatics with experimental validation. We demonstrated its dysregulation across cancers in a type-dependent manner, correlations with immune infiltration and tumor-associated pathways. Critically, qRT-PCR experiments confirmed the significant co-upregulation of ZFP36 and its functional network genes ( SOCS3 , JUN , SLC7A11 , CSRNP1 ) in LIHC, LUAD, and BRCA cell lines. These findings establish ZFP36 as a promising diagnostic and prognostic biomarker and suggest its role as a pivotal post-transcriptional regulator in tumorigenesis, supporting its potential for clinical application in cancer assessment.
Lyn governs the establishment and maintenance of B cell anergy by suppressing PI3K signaling
Multimodal evidence for hippocampal engagement and modulation by functional connectivity-guided parietal TMS
High-voltage and stable co-free LiNiO2 positive electrode for sulfide-based all-solid-state batteries
Differentiation of psychotic and affective disorder patients from healthy controls using the niacin skin flush test: a novel analytical method and the SKINREMS system—preliminary research
Abstract According to the phospholipid membrane theory of psychotic disorders, fatty acid metabolism may play a role in the etiopathogenesis of schizophrenia (SCH) and related disorders. Weakened skin reactions to niacin have been documented in SCH and bipolar disorder (BD), prompting research into biomarkers underlying these responses. So far, there is also no standard for performing and interpreting the niacin skin flush test (NSFT) which creates an opportunity for development in this area. The NSFT was conducted based on the SKINREMS system and an original method of analyzing measurements. 120 individuals including 33 patients diagnosed with first-episode psychosis (FEP), 22 with BD, 13 with schizoaffective disorder (SA), 13 with chronic schizophrenia (CS), and 39 healthy controls (HC) participated in the study. NSFT differentiated patients from HC and among subgroups of patients based on color saturation, specific time points, and niacin solution concentrations. The NSFT is a fast, effective, and cheap method that allows the differentiation of individuals suffering from psychotic disorders from HC. Standardization of the test method may contribute to more precise searches for biomarkers responsible of responses in the NSFT and can support the diagnostic process. The presented study is preliminary and exploratory in nature. Developing a method of using NSFT may contribute to a more precise search for biomarkers responsible for the results and thus to the diagnostic process.
Characterization and health index assessment of 34.5 kV cross-linked polyethylene (XLPE) power cables
Settlement heritage on the Coastal Peninsula: an investigation of the spatiotemporal evolution of Shandong Province via GIS
Comparing placement and polarity configurations of a two-magnet fingertip vibrotactile device
Abstract Vibrotactile feedback enriches the use of wearable technologies for entertainment, navigation, and healthcare. The actuators of these portable systems, particularly fingertip devices, need to be compact, comfortable, and easy to integrate. Multiple vibrating elements could enhance perceptual realism, but how should they be arranged and oriented on the fingerpad? Here, we evaluate a simple approach that uses an audio input signal to drive an air coil that vibrates two magnets embedded in a soft fingertip sheath; the magnets are arranged in the radial-ulnar or proximal-distal direction with either the same or opposite polarity. We explore the effects of these new device configurations on both dynamic response and haptic perception. Experimental results indicate that the vibrations were perceived well across frequencies, with stronger sensations between 180 and 360 Hz, which aligns with the high vibration magnitudes our computational simulation predicts in this frequency range. Interestingly, perceptual responses showed that participants mainly classified vibrations based on the excitation frequency rather than the polarity of the magnets. Participants also rated vibrotactile feedback derived from recorded sounds and replayed for different interactions. Their evaluations offer promising evidence that this actuation approach could be used in extended-reality applications to improve transient user interactions with virtual objects.