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Correction: A Progress-driven approach to cognitive outcomes after traumatic brain injury: A study protocol for advancing equity, diversity, and inclusion through knowledge synthesis and mobilization

Prevalence and associated factors of chronic kidney disease among diabetes mellitus patients in Ethiopia: A systematic review and meta-analysis

Introduction Chronic kidney disease (CKD) is a major public health concern worldwide, especially among people with diabetes mellitus (DM), which is the main cause of morbidity and mortality. In Ethiopia, the burden of CKD on DM patients is compounded by a variety of socioeconomic and healthcare-related issues. Despite the increased risk of developing CKD in DM patients, comprehensive studies on the prevalence and associated factors of CKD in this population are rare. To address this gap, this study aimed to estimate the pooled prevalence and associated factors of CKD among DM patients in Ethiopia. Methods This systematic review and meta-analysis was carried out through an investigation of published studies in Ethiopia. A systematic literature search was performed using electronic databases such as PubMed, EMBASE, Scopus, and Google Scholar. A random-effects model was used to estimate the pooled prevalence of CKD and the odds ratio (OR) with a 95% confidence interval. The I² statistic was used to measure heterogeneity among the included studies, with a p-value < 0.05 indicating statistical significance. Publication bias was evaluated via a funnel plot and Egger’s test, and subgroup, sensitivity, and meta-regression analyses were also performed. Results Out of the 19 included studies, the estimated pooled prevalence of CKD among DM patients in Ethiopia was 18% (95% CI 14.0, 22.0). In addition, age ≥ 60 years (OR = 3.07, 95% CI: 2.44, 3.87), rural residence (OR = 1.40, 95% CI: 1.01, 1.95), duration of DM > 5 years (OR = 2.47, 95% CI: 1.62, 3.77), proteinuria (OR = 3.30, 95% CI: 2.23, 4.88), HDL-C level < 40 mg/dL (OR = 3.08, 95% CI: 2.28, 4.16), and family history of CKD (OR = 2.58, 95% CI: 1.62, 4.09) were factors significantly associated with the prevalence of CKD among DM patients. Conclusion The prevalence of CKD in Ethiopia was high, affecting nearly two in five individuals with diabetes. In addition, factors such as older age, rural residence, longer DM duration, positive proteinuria, lower HDL-C levels, and a family history of CKD were significantly associated with CKD prevalence. Therefore, targeted public health interventions, such as screening, education, and awareness programs, are highly recommended to mitigate this problem. Systematic review registrations PROSPERO (2024: CRD42024576958).

Retraction: Analysis of the pattern recognition algorithm of broadband satellite modulation signal under deformable convolutional neural networks

Unraveling image construction by modality: Corpus-based diachronic insights into the reports to the Party Congress of China

Recent years have witnessed a “discursive turn” in image construction studies. This article explores the linguistic features of image construction. We provide a corpus-based diachronic study of the distribution of modality in The Reports to the 16th to 20th National Congress of the Communist Party of China and unravel the role of the modal verbs in conceptualizing China’s images in The Reports. To analyze the national image, we need to understand how the various elements in The Reports, i.e., actors, actions, and situations, are not only depicted but also intricately interconnected in terms of volition, obligation, and prediction. The diverse national image profiles can be discerned through the lens of how the actors perceive the situations in relation to what is deemed desirable, committed, possible, important, and expected in the context of The Reports. The study finds that The Reports, based on the frequency, value, category and translation of the modal verbs, can project different image profiles of the nation, such as a reliable planner, a committed and powerful leader, and an active participant showing respect for others.

How AI could let us watch epic star collisions in real time

Antifouling Spiky Nanoelectrodes Enhance Detection of Bacterial mRNA

Laser-Induced Alignment of Nanoparticles and Macromolecules for Coherent-Diffractive-Imaging Applications

Retraction: The data dimensionality reduction and bad data detection in the process of smart grid reconstruction through machine learning

How the brain decides whether to persist — and when to give up

Photoenolization of <i>α,β</i>-Unsaturated Esters Enables Enantioselective Contra-Thermodynamic Positional Isomerization to α-Tertiary <i>β,γ</i>-Alkenyl Esters

Correction: Examining infantile facial features and their influence on caretaking behaviors in free-ranging Japanese macaques (Macaca fuscata)

Combining Organic Cations of Different Sizes Grants Improved Control over Perovskitoid Dimensionality and Bandgap

Correction: Impact of feralization on evolutionary trajectories in the genomes of feral cat island populations

Sexual harassment allegations linked to drop in citations

Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein–Protein Interactions Using Phage Display

Correction: Yield of soybean genotypes identified through GGE biplot and path analysis

Excited State Covalency, Dynamics, and Photochemistry of Square Planar Ni-Thiolate Complexes Revealed by Ultrafast X-ray Absorption

Ebola and Marburg viruses IgG detections in small ruminants and dogs from villages within outbreak areas in Gabon

The Ebola virus (EBOV) and Marburg virus (MARV) have been in circulation in Africa for several decades and are the cause of numerous outbreaks. There has been very little research on the role of domestic animals in their transmission to humans, but studies have only been conducted in dogs and pigs where relatively high levels of IgG was detected. These levels suggest that ruminants, which have not been studied, should also be investigated. This study aims at evaluating the circulation of MARV and EBOV in dogs, sheep and goats and to assess their exposure to these two viruses. Between November 2018 and March 2023, a total of 448 domestic animal sera or plasma samples, including 128 dogs, 222 goats and 98 sheep, were analyzed by serological and molecular methods. The Luminex technique was employed for the detection of IgG antibodies against EBOV NP, GP, MARV GP and VP40, while EBOV specific and pan-filovirus polymerase chain reaction amplification was used for molecular analysis. All samples tested negative for EBOV and MARV RNA. However, our results showed that 2/128 (1.5%) dogs, 1/222 (0.4%) goats and 3/98 (3.1%) sheep displayed NP and GP anti-EBOV antibodies. In addition, 2/128 (1.5%) dogs displayed GP and VP40 anti-MARV antibodies, while no antibodies were detected in goats and sheep. Over all, these results suggest that dogs and small ruminants are naturally exposed to EBOV and MARV. In the absence of clinically sick individuals, the presence of IgG-positive animals suggests various sources of exposure, such as contaminated fruits with the urine and saliva of bats or dead bats fallen on the ground ate by dogs. These contaminated substrates are both consumed by both dogs and small ruminants. The findings provide new insights into the circulation and exposure of EBOV and MARV in domestic animals, emphasising their potential use as sentinels. Furthermore, they prompt significant considerations regarding the potential risk to humans in this region.

A Dual-Targeted Molecule for Disease-Activatable Proteolysis Targeting Chimeras and Targeted Radionuclide Therapy of Cancer

Causes, management and outcomes of polyhydramnios at a secondary level hospital in Cape Town, South Africa

Introduction Polyhydramnios is associated with both maternal and fetal adverse outcomes. Idiopathic polyhydramnios, regardless of its severity category, was considered not to be associated with an increase in adverse outcomes. In contrast, when conditions such as congenital and chromosomal abnormalities or diabetes mellitus are detected, neonatal and maternal adverse outcomes can be up to five times higher. We thus aimed to document the outcomes of patients with mild, moderate and severe polyhydramnios according to whether an underlying cause was found and which management protocol was followed. Methodology We conducted a retrospective cohort study of all patients with polyhydramnios on ultrasound examination at our secondary hospital between January 1, 2018 and December 31, 2020. Hospital folders were reviewed. We recorded demographic data, information on underlying causes, management and outcomes. We summarised categorical variables using count (percentage). We tested the association between categorical variables using the chi-square test. Statistical significance was set at p &lt; 0.05. Results A total of 136 patients with polyhydramnios (80 mild, 42 moderate, and 14 severe) were included. Most cases of polyhydramnios were idiopathic regardless of category [81.2% (65/80), 78% (32/42) and 78% (11/14) in the mild, moderate and severe groups, respectively]. The likelihood of occurrence of the composite adverse outcome, was higher with increasing severity of polyhydramnios, with 6.75%. 19.05%, and 35.71% in the mild, moderate and severe groups, respectively, having the composite adverse outcome (p =  0.01). Elective delivery before 40 weeks’ gestation for polyhydramnios in patients with idiopathic polyhydramnios was associated with a significant reduction in the occurrence of the composite adverse outcome compared to awaiting spontaneous labor (3.77% versus 15.79%, p =  0.036),. Conclusions Adverse outcomes were related to severity of the polyhydramnios and were significantly lower in the mild compared to the moderate and severe groups, with the rate of adverse outcome in the mild group comparable to that of the general population. Early delivery before 40 weeks gestation may be associated with benefit in moderate and severe groups of polyhydramnios.