Recent trends in electro-microfluidic devices for wireless monitoring of biomarker levels

Abstract

Wireless monitoring has emerged as a promising approach that enables real-time tracking of health, disease progression, and fitness, unlocking new possibilities for personalized healthcare. The review focuses on integrating electro-microfluidic (EM) devices with wireless technologies, revealing the potential for miniaturized, portable, and cost-effective systems. EM devices can noninvasively detect critical disease biomarkers such as metabolites, proteins, and pathogens. These advancements address the growing demand for accessible diagnostics, especially in resource-limited settings. Advancements in microfabrication techniques and biocompatible materials have enhanced the sensitivity, specificity, and ability of the devices to detect multiple biomarkers simultaneously, ensuring reliable performance in diverse applications. Incorporating Internet of Things frameworks further bridges the gap between laboratory diagnostics and point-of-care testing, enabling seamless data transmission and remote monitoring. Additionally, implementing flexible materials such as polymers, paper-based platforms, and textile-integrated designs has expanded the scope of devices to wearable applications, providing user comfort and convenience. These devices improve diagnostic accuracy and patient safety by enabling continuous health monitoring and early disease detection. The review highlights a comprehensive overview of the cutting-edge advancements in EM devices, emphasizing their transformative potential in making healthcare more accessible, efficient, and personalized.