Pushing the sensitivity of stimulated Raman scattering microscopy with quantum light: Current status and future challenges

Z Zicong Xu S Sho Nitanai K Kenichi Oguchi Y Yasuyuki Ozeki (Department of Electrical Engineering and Information Systems, The University of Tokyo 1 , Bunkyo, Tokyo 113-8656,)

Abstract

Quantum-enhanced stimulated Raman scattering (QE-SRS) microscopy sits at the intersection of biomedical imaging, laser microscopy, and quantum optics toward realizing sensitive molecular-vibrational imaging. This Perspective explores the current status of this emerging field, integrating viewpoints from these diverse disciplines to highlight its potential for advancing biological and medical imaging. We discuss key challenges and future directions in leveraging quantum light to push the sensitivity limits of SRS microscopy, paving the way for next-generation imaging modalities.

Article Details

Volume / Issue Vol. 127, Issue 4
Published July 28, 2025
ISSN 0003-6951
Publisher American Institute of Physics

Journal Info

Applied Physics Letters

American Institute of Physics

ISSN: 0003-6951 Physical Sciences

Authors (4)

Z

Zicong Xu

S

Sho Nitanai

K

Kenichi Oguchi

Y

Yasuyuki Ozeki

Department of Electrical Engineering and Information Systems, The University of Tokyo 1 , Bunkyo, Tokyo 113-8656,