Computationally designing a dual-aspheric compound lens toward multi-depth endomicroscopy imaging

B Bingxin Shen (School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,) Z Zixian Cao (School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,) Y Yankan Huang (School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,) J Jiapeng Zhu H Haiyan Huang W Wenxuan Liang (School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,)

Abstract

This study presents a computational approach for designing a compound lens system by pairing two infinity-corrected aspheric lenses with matching ray-mapping conditions to enable three-dimensional imaging over an extended volume with minimal aberrations. The surface profiles of each aspherical lens are derived by solving explicit differential equations, reducing dependence on prior optical design expertise. We explore different combinations of the aspheric lenses to create compound lenses that satisfy the Abbe sine or Herschel's condition, validating their tolerance to lateral and axial object point shifts. This computational design approach offers a low-barrier, cost-effective solution for rapidly fabricating miniature objectives and prototyping unconventional optical sectioning endomicroscope designs.

Article Details

Volume / Issue Vol. 126, Issue 22
Published June 02, 2025
ISSN 0003-6951
Publisher American Institute of Physics

Journal Info

Applied Physics Letters

American Institute of Physics

ISSN: 0003-6951 Physical Sciences

Authors (6)

B

Bingxin Shen

School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,

Z

Zixian Cao

School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,

Y

Yankan Huang

School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,

J

Jiapeng Zhu

H

Haiyan Huang

W

Wenxuan Liang

School of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China 1 , Hefei, Anhui 230026,