A statistical test for the benefits of personalizing interventions

Z Zhaoqi Li E Emma Brunskill (Computer Science Department, Stanford University, Stanford, CA, USA.)

Abstract

From medicine to marketing to social sciences, the promise of tailoring interventions to individuals is undeniable. However, practical applications force weighing personalization’s potential benefits with its possible increased cost and fragility. We introduce a statistical hypothesis test that evaluates, given historical data, evidence that a personalized intervention policy’s performance will surpass deploying the best single intervention. The test maintains strict Type I error control while achieving asymptotic normality with the minimal possible variance under specified conditions. Results on diverse datasets from job training, depression treatment, education, and recommendation systems demonstrate the test’s versatility and its superior performance over alternatives. This test can support decision-makers throughout the intervention sciences by providing a simple and powerful quantification of the potential benefits of personalization.

Article Details

Journal Science
Volume / Issue Vol. 393, Issue 6807
Published July 09, 2026
ISSN 0036-8075
Publisher American Association for the Advancement of Science

Journal Info

Science

American Association for the Advancement of Science

ISSN: 0036-8075 Social Sciences

Authors (2)

Z

Zhaoqi Li

E

Emma Brunskill

Computer Science Department, Stanford University, Stanford, CA, USA.