Scientific Reports

Study of caspase-6 activity in aggressive HCT116 cells using methotrexate-encapsulated lactoferrin-conjugated solid lipid nanoparticles via in silico and in vitro approaches

Sankha Bhattacharya, Ranajit Nivrutti Shinde, Vishal Beldar et al. Jul 01, 2025 10.1038/s41598-025-08089-w

Automatic generation control optimization for power system resilience under real world load variations using genetic algorithm

Muhammad Ayaz, Dur-e-Zehra Baig, Syed Muhammad Hur Rizvi et al. Jul 01, 2025 10.1038/s41598-025-03608-1

Control of motor coordination by transient receptor potential melastatin 8 through γ-aminobutyric acidergic circuit modulation in the male mouse cerebellum

Mayuka Koyama, Koki Harada, Naoko Takizawa et al. Jul 01, 2025 10.1038/s41598-025-98837-9

Exhaust manifold performance enhancement using nano fluids a design and CFD investigation for four stroke petrol engines

R. Ramesh Kumar, K. Karthik, P. V. Elumalai et al. Jul 01, 2025 10.1038/s41598-025-99747-6

Utilizing a deep neural network for robot semantic classification in indoor environments

Tareq Alhmiedat, Osama Moh’d Alia Jul 01, 2025 10.1038/s41598-025-07921-7

A network meta-analysis of efficacy and safety of adjuvant targeted therapy or immunotherapy in non-small cell lung cancer

Sunatee Sa-nguansai, Sasivimol Rattanasiri, Prapaporn Pornsuriyasak et al. Jul 01, 2025 10.1038/s41598-025-05823-2

Sex differences in the association of physical activity patterns with all-cause and cardiovascular mortality: a prospective cohort study from NHANES 2007–2018

Ailing He, Yunkai Wang, Chaopin Du et al. Jul 01, 2025 10.1038/s41598-025-06056-z

Influence of temperature and excitation density on carrier dynamics in CdZnTe quantum dots

Minh Tan Man, Hong Seok Lee Jul 01, 2025 10.1038/s41598-025-07292-z

Using graph neural network and symbolic regression to model disordered systems

Ruoxia Chen, Mathieu Bauchy, Wei Wang et al. Jul 01, 2025 10.1038/s41598-025-05205-8

Abstract The key to modeling disordered systems lies in accurately simulating atomic trajectories, typically achieved through molecular dynamic (MD) simulation. The accuracy of MD simulation...

Effects of inflammation on hypoxic renal tubular epithelial cell injury under high-glucose conditions and the regulatory role of miR-125b

Xin Shen, Yang Liu, Jiahui Zhao et al. Jul 01, 2025 10.1038/s41598-025-05701-x

Effect of nano liposomal herbal extracts against biofilm formation and adherence of streptococcus mutans

Milad Baseri, Amirreza Naseri, Faraz Radmand et al. Jul 01, 2025 10.1038/s41598-025-08856-9

Knowledge attitudes and practices of healthcare professionals regarding diabetes self management education and support

Qin Wang, Guihua Miao, Shulan Miao et al. Jul 01, 2025 10.1038/s41598-025-08537-7

Enterprise fission path optimization and dynamic capability construction based on the soft actor-critic algorithm

Hengsheng Gu Jul 01, 2025 10.1038/s41598-025-06180-w

Integrated analysis identifies key genes underlying the bidirectional association between depression and renal failure

Zhengqi Qiu, Yu Nie, Xu Lin et al. Jul 01, 2025 10.1038/s41598-025-04707-9

Abstract Depression is a common psychiatric comorbidity in individuals with end-stage renal disease (ESRD). However, the underlying biological mechanisms and the precise relationship between...

Preparation and property evaluation of oral colon targeted protein delivery system with sodium alginate and chitosan

Long Ma, Wentao Zhou, Xizhi Ma et al. Jul 01, 2025 10.1038/s41598-025-04983-5

Wave convergence principles of agricultural carbon emission efficiency: a multi-level urban agglomeration study

Xu Wei, Qixin Ma, Xiaoqun Chen Jul 01, 2025 10.1038/s41598-025-06649-8

Research on a denoising model for entity-relation extraction using hierarchical contrastive learning with distant supervision

Ayiguli Halike, Aishan Wumaier, Kahaerjiang Abiderexiti et al. Jul 01, 2025 10.1038/s41598-025-04474-7

Abstract Distant supervision is a technique that utilizes knowledge base information to automatically generate labels for text samples, enabling the large-scale creation of labeled d...

Genetic evidence suggests a causal relationship linking thyroid function to prospective memory and dementia and Parkinson’s disease

Yang Wang, Yanying Liu, Huimin Yang et al. Jul 01, 2025 10.1038/s41598-025-01596-w

Loneliness is related to facial emotion perception in people with HIV

Moka Yoo-Jeong, Rebecca E. Easter, Jennifer M. Coughlin et al. Jul 01, 2025 10.1038/s41598-025-04237-4

Characterizations of sulfate-reducing bacteria biofilm formed on N80 carbon steel in artificial shale gas field produced water

Lincai Peng, Shaomu Wen, Lei Yu et al. Jul 01, 2025 10.1038/s41598-025-04332-6

Abstract The corrosion of steel caused by sulfate-reducing bacteria (SRB) has been a big trouble resulting in the service failure of engineering equipment, and SRB biofilm is the direct reas...

Preparation and analysis of structural, morphological and optical properties of BaFeO2.67/Fe2O3 nanocomposite

Adnan Alnehia, Annas Al-Sharabi, Muhammad Hadi et al. Jul 01, 2025 10.1038/s41598-025-02908-w

Altered miRNA expression in the lesions of cutaneous leishmaniasis caused by L. major and L. tropica with insights into apoptosis regulation

Taha Masoudsinaki, Shima Hadifar, Hamzeh Sarvnaz et al. Jul 01, 2025 10.1038/s41598-025-03802-1

Abstract Leishmaniasis is a vector-borne infectious disease that affects many subtropical countries. Leishmania (L.) major and L. tropica are among the old-world causative agents and cause c...

Detecting heavy trucks from mobile phone trajectories using image-based behavioral representations and deep learning models

Franco Basso, Félix des Rotours, Tomás Maldonado et al. Jul 01, 2025 10.1038/s41598-025-06711-5

Therapeutic evaluation of Martynia annua derived carbon dots in epileptic Drosophila model

Megha B. Abbigeri, Muskan Khan, Bothe Thokchom et al. Jul 01, 2025 10.1038/s41598-025-07780-2

Abstract This study investigates the synthesis and characterization of Carbon dots (MA-CDs) derived from the aqueous extract of Martynia annua and examining their potential effects in an epi...

Simplistic synthesis of L-Serine-ZnS composites with distinct morphological nature, enhanced thermal stability and superior photocatalytic enactment for ciprofloxacin removal

Aimon Hossain Faisal, Mohammad Mizanur Rahman Khan, Jae-Ho Jeong Jul 01, 2025 10.1038/s41598-025-05208-5

Articles in this Issue