Scientific Reports

Single-cell RNA sequencing analysis revealed the immunosuppressive remodeling of tumor-associated macrophages mediated by the MIF-CD74 axis in gastric cancer

Weiwei Liu, Chuangyuan Wang, Lixin Liang et al. Jul 24, 2025 10.1038/s41598-025-10301-w

Machine learning analysis of molecular dynamics properties influencing drug solubility

Zeinab Sodaei, Saeid Ekrami, Seyed Majid Hashemianzadeh Jul 24, 2025 10.1038/s41598-025-11392-1

Community phylogenetic diversity drives flowering synchrony among coexisting plant species even under drought conditions

Arantzazu L. Luzuriaga, Rocío Chaves, Pablo Ferrandis et al. Jul 24, 2025 10.1038/s41598-025-12414-8

Disease probability-enhanced follow-up chest X-ray radiology report summary generation

Zhichuan Wang, Qiao Deng, Tiffany Y. So et al. Jul 24, 2025 10.1038/s41598-025-12684-2

Abstract A chest X-ray radiology report describes abnormal findings not only from X-ray obtained at a given examination, but also findings on disease progression or change in device placemen...

Global trends and influential factors of climate change adaptation recognition in GDELT

Muhammad Mudassar, Tao Lin, Xiaotong Wang et al. Jul 24, 2025 10.1038/s41598-025-11794-1

Uncovering sequence effects in Titanium binding peptides adsorption on TiO2: A molecular dynamics study

Roja Rahmani, Alexander P. Lyubartsev Jul 24, 2025 10.1038/s41598-025-10966-3

Abstract Titanium binding peptides are useful tools for material functionalization in both biomedical and nanotechnology applications because of their ability to...

Comparative transcriptome analysis reveals the potential mechanism of seed germination promoted by trametenolic acid in Gastrodia elata Blume

Jie Liu, Wangyang Ye, Danyang Wang et al. Jul 24, 2025 10.1038/s41598-025-12269-z

Integrative approach to the systematics of the endemic Svalbard aphid specis Macrosiphum calvulum (Hemiptera, Aphididae) using molecular morphological and reproductive system analysis

Karina Wieczorek, Dominik Chłond, Łukasz Chajec et al. Jul 24, 2025 10.1038/s41598-025-12913-8

Detection of breast cancer using machine learning and explainable artificial intelligence

Tharunya Arravalli, Krishnaraj Chadaga, H Muralikrishna et al. Jul 24, 2025 10.1038/s41598-025-12644-w

Abstract Breast cancer is characterized by the proliferation of abnormal breast cells that eventually turn into malignant tumors. These cancer cells can metastasize to be life-threat...

Validation of the Arabic ADHD rating Scale-5 for adolescents in Saudi Arabia using structural equation modeling

Mohammed M. J. Alqahtani, Nouf MohammedAl Saud, Nawal Mohammed Alsharef et al. Jul 24, 2025 10.1038/s41598-025-12976-7

Comparative chromium adsorptive capacity of different low-cost materials using fixed bed column

Asma Shakeel, Inayat Mustafa Khan, Faheem Jeelani et al. Jul 24, 2025 10.1038/s41598-025-12076-6

Research on cognitive reliability model considering crew influence in main control room of digital nuclear power plant

Xueyang Liu, Jianqiao Liu, Zhaoxu Meng et al. Jul 24, 2025 10.1038/s41598-025-12885-9

Pharmacological Evaluation of active compounds in papaya associated with thrombocytopenia inhibition in dengue patients through in silico approaches

Md. Anisur Rahman, Guilherme Bastos Alves, Gabriel Vinícius Rolim Silva et al. Jul 24, 2025 10.1038/s41598-025-09835-w

The role of microplastics as vectors of antibiotic contaminants via a molecular simulation approach

Sedigheh Abdollahi, Heidar Raissi, Farzaneh Farzad Jul 24, 2025 10.1038/s41598-025-12799-6

Musculoskeletal disorders among computer user workers in Ethiopia: a systematic review and meta-analysis

Biruk Demissie, Gebrehiwot Berie Mekonnen, Tigabu Munye Aytenew Jul 24, 2025 10.1038/s41598-025-96470-0

Simulating population dynamics of sea turtles in a high survival world

Michael D. Arendt, Jeffrey A. Schwenter Jul 24, 2025 10.1038/s41598-025-10482-4

Significant prognostic value of cell-cycle proteins in early-stage small cell carcinoma of cervix

Qing Xu, Hongyu Zhou, Jiao Wu et al. Jul 24, 2025 10.1038/s41598-025-12112-5

Structural bioinformatics approaches for predicting novel drug targets in hepatitis C virus proteins: a comprehensive analysis

Miao Qu, Mingzhu Gao, Xisheng Sang et al. Jul 24, 2025 10.1038/s41598-025-12563-w

Abstract This study employs structural bioinformatics approaches to identify and evaluate potential drug targets within the Hepatitis C virus (HCV) proteome. Through integration of homology...

The ferroptotic effect of NRF2-GCLM signaling axis derived by radiotherapy of esophageal squamous cell cancer: the vivo study

Yiliyaer Nuerrula, Zhaoyuan Xue, Aidiye Tiliwalidi et al. Jul 24, 2025 10.1038/s41598-025-10414-2

Abstract Nuclearfactor erythroidderived 2-like 2(NRF2) is a major regulator of the body’s antioxidant defense system and a key protein in the process of ferroptosis, which is upregulated in...

Green tea dye ligands to transfer toxic lead metal ions to precipitated metal complexes for polymer composite applications

Dana S. Muhammad, Dara M. Aziz, Shujahadeen B. Aziz Jul 24, 2025 10.1038/s41598-025-12609-z

In silico and in vitro investigations reveal pan-PPAR agonist activity and anti-NAFLD efficacy of polydatin by modulating hepatic lipid-energy metabolism

Sumit Kumar Mandal, Mohammed Muzaffar-Ur-Rehman, Sonakshi Puri et al. Jul 24, 2025 10.1038/s41598-025-12357-0

Abstract Polydatin (PD), a stilbenoid resveratrol-derivative in Vitaceae, Liliaceae, and Leguminosae, exhibits pharmacological protection in metabolic disorders. This study investigated Poly...

The impact of parity on the risk of nonalcoholic fatty liver disease defined by hepatic steatosis index: A nationwide cohort study

So-hyeon Hong, Soon Young Hwang, Ji Hee Yu et al. Jul 24, 2025 10.1038/s41598-025-11976-x

Articles in this Issue