Scientific Reports

Vol. 15, Issue 1 Issue 1 2026
45807
Articles

Articles in this Issue

Design and optimization of intranasal aripiprazole-loaded nanostructured lipid carriers for enhanced brain targeting in schizophrenia: in vitro and ex vivo evaluation

Mohamed Rahamathulla, R. Bindiya, M. P. Venkatesh et al. Dec 22, 2025 10.1038/s41598-025-32985-w

Robust securable economic operation of grid-connected renewable integrated energy system with hydrogen storage and electric and fuel cell vehicles

Hadi Varei, Hadi Zayandehroodi, Mehdi Jafari Shahbazzadeh et al. Dec 22, 2025 10.1038/s41598-025-26984-0

Differential expression genes in the eye-transcriptomes of the riverine and marine grass puffer (Takifugu niphobles)

Misa Osada, Yohey Terai Dec 22, 2025 10.1038/s41598-025-28000-x

Rifaximin improves anxiety- and depression-like behaviors in rats by regulating NPY in the colon and mPFC

Qian Luo, Haonan Li, Yihe Wang et al. Dec 22, 2025 10.1038/s41598-025-27826-9

Fuzzy logic and deep learning approach for automated white blood cell detection and classification via multi-CNN feature fusion

Taseer Ullah, Khalil Ullah, Parvez Khan et al. Dec 22, 2025 10.1038/s41598-025-28354-2

A novel approach to design compact, wideband, and high-gain circularly polarized MIMO antenna using dual-polarized elements and hybrid couplers

H. Tran, Phuong Kim-Thi, Nguyen Tran et al. Dec 22, 2025 10.1038/s41598-025-32097-5

L-ascorbate prevents non-alcoholic steatohepatitis-based hepatocarcinogenesis in Sod1/Prdx4 double-knockout mice

Tsukasa Osaki, Takujiro Homma, Yuki Maeda et al. Dec 22, 2025 10.1038/s41598-025-28982-8

Low power and high-speed quadrate node upset tolerant latch design using CNTFET

Shaik Asiya, Satheesh Kumar S Dec 22, 2025 10.1038/s41598-025-28311-z

A hybrid SERWI ensemble model for crop yield prediction using an inverse RMSE weighting strategy

Adhithi Ravikumar, Vishnusri Periyasamy, Keerthanah Mahendran Kamala Devi et al. Dec 22, 2025 10.1038/s41598-025-31987-y

Abstract Accurate crop yield prediction is critical for informed agricultural planning, food distribution, and policy formulation. Traditional statistical models often fail to captur...

Staged and geometry-adapted support for coal mine roadways under weak rock conditions: a numerical study

Yu Guo, Qinghua Ma, Shuai Zhong Dec 22, 2025 10.1038/s41598-025-30587-0

Abstract Controlling large deformation and instability of roadways in weak coal seams remains a critical challenge for safe and efficient mining operations. This study carried out an...

Effectiveness of village doctors led cognitive behavioral therapy for COPD patients in a randomized controlled trial

Maowei Zhang, Pan Zhang, Zongmei Dong et al. Dec 22, 2025 10.1038/s41598-025-31119-6

An enhanced adaptive image steganography method using block skin-maps and the integer S-transform

Amal Khalifa, Doaa Sami Khafaga, Mennatallah Sadek et al. Dec 21, 2025 10.1038/s41598-025-16176-1

Global prevalence of occult hepatitis B virus infection in HBcAb-positive individuals: a systematic review and meta-analysis

Yuting Yang, Huiwu Xing, Guojin Wu et al. Dec 21, 2025 10.1038/s41598-025-23207-4

Neurally adjusted ventilatory assist vs pressure support ventilation: short-term effects on shunt and dead space after cardiac surgery

Andreas Martinsson, Carl Lundholm, Sven-Erik Ricksten et al. Dec 21, 2025 10.1038/s41598-025-33097-1

Abstract Postoperative pulmonary complications, particularly atelectasis, are common after cardiac surgery and may contribute to impaired gas exchange or acute l...

Optimization of comprehensive wheat growth index system and monitoring model based on LAI

Mingguang Diao, Shuning Liang, Jianing Chen et al. Dec 21, 2025 10.1038/s41598-025-25313-9

Solar forcing on elemental and nanomechanical variations in Late Cretaceous lacustrine deposits

Yuke Liu, Xiaomei Wang, Kunning Cui et al. Dec 21, 2025 10.1038/s41598-025-27521-9

Abstract Decennial to annual-scale paleoclimate proxy variations are often attributed to solar forcing and/or unforced internal climate oscillations, but recognition of such variatio...

Decoding the relationships among miRNA, HPV infection, and tumor suppressor gene expression in breast cancer patients

Zana Naderi, Malihe Hamidzade, Amir Hossein Yari et al. Dec 21, 2025 10.1038/s41598-025-26622-9

Experiments and physical Investigation on the adsorption of methylene on activated carbon

Souhail Mohammed Bouzgarrou, Hedi Jedli, Rym Hassani et al. Dec 21, 2025 10.1038/s41598-025-31120-z

TRPV1 deletion in male mice alters cardiomyocyte ultrastructure without affecting baseline cardiac function

Nolwenn Tessier, Lucille Païta, Christophe Chouabe et al. Dec 21, 2025 10.1038/s41598-025-28521-5

Abstract The Transient Receptor Potential Vanilloid 1 (TRPV1) channel is implicated in various cardiovascular processes, including nociception, inflammation, and...

Overactive bladder phenotype induced by chronic activation of hypothalamic neuroendocrine stress pathways in rats with no extrinsic behavioral stress applied

Jenan Husain, Alexandra Bakhareva, Anna Pace et al. Dec 21, 2025 10.1038/s41598-025-32428-6

Abstract Overactive urinary bladder (OAB) negatively impacts quality of life, and stress is known to play a key role in its development. However, the mechanisms linking stress to OAB...

Exploring the expression and prognostic roles of LAD1 in lung adenocarcinoma

Sufen Wang, Banghong Qiang, Xiaoyan Xu et al. Dec 21, 2025 10.1038/s41598-025-33277-z

Abstract Lung adenocarcinoma (LUAD) is a common subtype of non-small cell lung cancer (NSCLC) with a poor prognosis. To identify novel biomarkers and understand the underlying mechan...

Hybrid micromagnetic and atomistic modeling of magnetization dynamics induced by engineered defects

Nastaran Salehi, Olle Eriksson, Johan Hellsvik et al. Dec 21, 2025 10.1038/s41598-025-31866-6

Abstract This study presents a 3D version of multiscale approach for investigating magnetization dynamics in multiscale, hybrid micromagnetic-atomistic simulations. The present work...

From monochromatic waves to realistic tides: deep learning for short-term forecasting of coastal ocean

Irem Yildiz, Emil V. Stanev, Joanna Staneva Dec 21, 2025 10.1038/s41598-025-31670-2

Abstract In this study, a hybrid architecture combining convolutional neural networks for spatial reconstruction and long short-term memory networks for temporal forecasting is used...

Interplay Between Enteroendocrine Hormone (Leptin) and Adipokines (Ghrelin and Adiponectin) with Gastric Expression of FTO and MC4R Genes

Mohamed Hany, Mona K. ElDeeb, Ehab Elmongui et al. Dec 21, 2025 10.1038/s41598-025-29899-y

Abstract Obesity is a complex, multifactorial disease influenced by genetic, hormonal, and metabolic factors. The fat mass and obesity-associated (FTO) and melan...

Irisin activates the AMPK-Beclin1 signaling pathway to regulate pulmonary autophagy induced by CSE + LPS

Zelin Chen, Siyu Wu, Zina Bai et al. Dec 21, 2025 10.1038/s41598-025-31824-2

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Journal Info

Publisher Nature Portfolio
ISSN 2045-2322
Subject Life Sciences
Language English
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