Scientific Reports

The mechanism of luteolin suppressing pancreatic cancer (PC) via cyclin B1 (CCNB1)-mediated signalling

Optical deformation measurement for thin-walled honeycomb structure with contacting cell walls under loading based on color image processing

Assessing behavioral control across the adult lifespan using a novel outcome revaluation task

Abstract While many studies have investigated the effects of aging on cognition, relatively few have examined aging impacts on habitual behavioral control. To assess these relationsh...

Trends of ciprofloxacin use in Kazakhstan, impacts of COVID-19, and strategies for AMR control

The mediating effect of urban water system climate resilience in the impact of sponge city pilot policy on ecological welfare

New species of Dolomedes (Araneae: Dolomedidae) from Kerala, India with insights on Indian records of the genus

Gender effects and racial biases in mate selection as revealed by machine learning

Coupling between water resource constraints and agricultural sustainability in Henan Province, China

Software cost estimation using TabNet and Harris Hawks Optimization

Qualitative phenomenological exploration of lived experiences and perspectives of Chinese hospital administrators engaged in medical dispute management

Archaic humans in the Middle Palaeolithic Levant conducted planned and selective intercepts of aurochs, but not mass hunting

Abstract While archaeologically challenging, determining whether hominins practised mass hunting before ca. 50,000 years ago is crucial for demonstrating intergr...

A continuous-wave photon-pair source operating in L-band through spontaneous four-wave mixing in birefringent ZBLAN fiber

UGP2 is a potential target for breast cancer, based on bioinformatics analysis and in vitro experiments

Modeling loess collapsibility using oedometer tests for foundation and pile settlement prediction

Leveraging magnetic resonance imaging to assess biocompatible scaffolds diffusion and flow-driven perfusion for lab-on-a-chip systems

The pitfalls of multiple-choice questions in generative AI and medical education

Assessment of cytotoxicity of some synthetic compounds against breast carcinoma spheroids with subsequent analysis of pro-apoptotic and gene expression

Abstract The current study examined the anticancer potential of 80 synthetic organic compounds at 50µM using in vitro two-dimensional (2D) and three-dimensional...

The role of AIM2 inflammasome pathway-mediated pyroptosis on brain injury induced by severe acute pancreatitis in mice

Oxidative stress reactivates androgen receptor signaling via USP36 to drive castration resistance in prostate cancer

Swallowing and choking difficulties as potential markers of FXTAS progression in FMR1 premutation carriers

Abstract Fragile X-associated tremor/ataxia syndrome (FXTAS) affects motor and coordination pathways and is linked to swallowing and choking difficulties, which...

Comparing postoperative outcomes of three-dimensional versus traditional microscopic vitrectomy and subretinal rt-PA injection for submacular hemorrhage

Fabrication of curcumin-loaded emulgel and its application in low-calorie and functional cake

Root cause analysis investigation of visible particulates in therapeutic protein drug products using morphologically directed Raman spectroscopy

Abstract Visible particulate (VP) matter in therapeutic protein drug products (DPs) is a quality attribute that can impact product efficacy and patient safety across the product life...

Pelvic floor muscle exercise practice and its determinants among postpartum women in Central Ethiopia: as a strategy for preventing pelvic floor disorders

Bacterial vaginosis, vaginal Candida colonization and antifungal susceptibility patterns in pregnant women of eastern Ethiopia: a prospective study