Scientific Reports

Vol. 16, Issue 1 Issue 1 2026
24336
Articles

Articles in this Issue

Proteomic profiling reveals age-related changes in transporter proteins in the human blood–brain barrier

Xujia Zhou, Mina Azimi, Niklas Handin et al. Dec 26, 2025 10.1038/s41598-025-31224-6

Abstract The Blood–Brain Barrier (BBB) is a selective barrier that regulates the entry of molecules including nutrients, environmental toxins, and therapeutic medications into the br...

Detection and diagnosis of diabetic retinopathy in retinal fundus images using agentic AI approaches

R. Sathya, A. Valaramathi Dec 26, 2025 10.1038/s41598-025-34016-0

Catechin hydrate induces GFAP expression and astrocyte branch elongation in rat neural stem cells

Hnin Wutyi Soe, Hyun-Jung Kim Dec 26, 2025 10.1038/s41598-025-30977-4

Convolutional neural network approach for automated well zonation in the Lower Bahariya member north Western Desert Egypt

Khaled Saleh, Walid M. Mabrouk, Ahmed M. Metwally Dec 26, 2025 10.1038/s41598-025-32119-2

Abstract Accurate well-to-well stratigraphic zonation is fundamental to subsurface reservoir characterization, particularly in geologically complex settings such as tidal channel sys...

Copper immobilized MIL-125-NH2 as an efficient nanocatalyst for click reaction and synthesis of benzo[b]pyrans

Zeynab Sadati, Heshmatollah Alinezhad, Mahmood Tajbakhsh Dec 26, 2025 10.1038/s41598-025-33201-5

Cost-utility and budget impact analysis of desmopressin for treating monosymptomatic nocturnal enuresis in Thai children

Nattanichcha Kulthanachairojana, Pantira Parinyarux, Parnnaphat Luksameesate et al. Dec 26, 2025 10.1038/s41598-025-32790-5

Trends in problematic gambling among school-aged adolescents based on three Spanish nationwide population-based studies (2018–2023): a gender-based analysis of risk and protective factors

Domingo Palacios-Ceña, Lidiane Lima Florencio, María Palacios-Ceña et al. Dec 26, 2025 10.1038/s41598-025-33561-y

A hybrid multi-scale indirect vision detector algorithm for heritage building fire detection

Jian Liang, Junsheng Cheng Dec 26, 2025 10.1038/s41598-025-31278-6

Triple-negative complementary metamaterial for ultrasound transmission through elastic barrier

Ki Yong Lee, Wonju Jeon Dec 26, 2025 10.1038/s41598-025-29656-1

Pyridoxamine inhibits dopamine-induced α-synuclein oligomerization through scavenging neurotoxic dopamine quinone

Seon Hwa Lee, Naoya Matsumoto, Akane Terada et al. Dec 26, 2025 10.1038/s41598-025-31292-8

An improved steel defect detection model using multi-scale feature fusion based on YOLO-MFD

Yuqin Feng, Lingxiao Jin, Hao Yang et al. Dec 26, 2025 10.1038/s41598-025-29596-w

Effects of artificial tears on ocular surface symptoms and visual task performance in digital device users

Sara Ortiz-Toquero, Irene Sanchez, Raul Martin Dec 26, 2025 10.1038/s41598-025-22510-4

A sensor-fused BIM-based ıntelligent control system for energy-efficient ındoor environmental regulation using deep actor-critic reinforcement learning (DACRL)

Libin Tong Dec 26, 2025 10.1038/s41598-025-30460-0

Establishing molecular biomarkers for efficient demarcation of tumor and non-tumor tissue in oral squamous cell carcinoma

Kashish Gupta, Ishan Raval, Apurvasinh Puvar et al. Dec 26, 2025 10.1038/s41598-025-33758-1

Abstract Oral squamous cell carcinoma (OSCC), which accounts for 90% of head and neck cancers ( HNSC), is a prevalent can...

Patellar shape diversity as a functional indicator of locomotor specialization in selected ruminant species

Oya Kahvecioğlu, Burak Ünal, Barış Can Güzel et al. Dec 26, 2025 10.1038/s41598-025-33370-3

A case study of the application of AI to early stage drug discovery

Abbi Abdel-Rehim, Larisa N. Soldatova, Ross D. King Dec 26, 2025 10.1038/s41598-025-32805-1

Abstract Artificial intelligence (AI) has emerged as a powerful tool in drug discovery, offering the potential to expedite the design of novel therapeutics. This study evaluates the...

Enhanced feature dynamic fusion gated UNet for robust retinal vessel segmentation

Yang Yang, Yifeng Li, Jikui Wang et al. Dec 26, 2025 10.1038/s41598-025-33694-0

Abstract This study proposes a Deep learning model, the Enhanced Feature Dynamic Fusion-Gated U-Net (EFDG-UNet), for retinal vessel segmentation. To address challenges in segmenting...

In vitro assessment of an antimicrobial peptide against Acinetobacter baumannii persister cells

Mandana Hosseini, Farzaneh Hosseini, Nour Amirmozafari et al. Dec 26, 2025 10.1038/s41598-025-33137-w

Abstract The rise of multidrug-resistant and persister cell populations of Acinetobacter baumannii (...

Seasonal rainfall and land-use impacts on microplastic characteristics in an endangered salmon stream

Tsan-Yang Hu, Wen-Hui Kuan Dec 26, 2025 10.1038/s41598-025-33600-8

Semantic decentralized authentication for IoT-based e-learning using Hedera Hashgraph and Knowledge Graphs

Lixia Luo, Yusha Zhang, Qitao Tang Dec 26, 2025 10.1038/s41598-025-33206-0

Sociodemographic variation and childhood predictors of showing love and care for others in 22 countries

Matthew T. Lee, Renae Wilkinson, Katelyn N. G. Long et al. Dec 26, 2025 10.1038/s41598-025-31380-9

Abstract Showing love and care for other people is a vital aspect of human relationships. However, little is known about how levels of love/care expression diffe...

A decision making algorithm for economic growth in the digital economy using CRITIC WASPAS based circular picture fuzzy information

Junguang Gao, Ziyao Lin, Quan Liu Dec 26, 2025 10.1038/s41598-025-31078-y

Abstract In this study, we explore the use of fuzzy set (FS) theory to address uncertainty in evaluating strategies that drive economic growth within the digital economy. Specificall...

Green approach in saponin extraction from Acanthophyllum caryophyllaceae root based on ultrasonication coupled with solvent extraction method and its lyophilization

Sama Yavarzadeh, Hoda Jafarizadeh-Malmiri, Omid Ahmadi Dec 26, 2025 10.1038/s41598-025-33732-x

A linear programming framework for optimizing molecular combinations of asphalt four components

Jie Zhu, Chuyuan Wen, Sijie Tao Dec 26, 2025 10.1038/s41598-025-33654-8

ATF3 overexpression is associated with cardiac hypertrophy and electrical dysfunction accompanied by enhanced cardiac cell proliferation in zebrafish

Eunmi Kim, Jinho Kim, Hyun-Yi Moon et al. Dec 26, 2025 10.1038/s41598-025-33025-3

Abstract Activating transcription factor 3 (ATF3) is a crucial regulator of gene expression in response to physiological stress across various tissues. Abnormal...

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Journal Info

Publisher Nature Portfolio
ISSN 2045-2322
Subject Life Sciences
Language English
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