Nature Communications
Articles in this Issue
Declining demand and circular transition possibilities of sand, gravel and crushed stone in China
Using in-situ small-angle scattering to reveal the structure and dynamics of supramolecular polymers
Abstract Small-angle scattering (SAS) is widely applied to nanoscale soft and hard material systems but has found limited use in the emerging field of supramolecular polymers (SPs)....
Modular esterification of unstrained carbonyls through palladium-catalyzed alkyne bridging C-C bond activation
Global sampling decline erodes science potential of natural history collections
Abstract The world’s natural history collections hold over two billion specimens, representing a unique spatial and taxonomic record of biodiversity on Earth over time. In recent dec...
11-bit two-dimensional floating-gate memories
Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation
Abstract Astrocytes are central to the pathogenesis of multiple sclerosis (MS); however, their regulation by post-translational ubiquitination and deubiquitinati...
Leveraging platinum-protein interactions to overcome chemoresistance
Abstract A common mechanism by which cancer cells acquire resistance to chemotherapeutics is through the overexpression of efflux pumps, enabling the removal of cytotoxic agents, suc...
Eosinophil-derived interleukin-24 compromises epithelial integrity and aggravates airway remodeling in mouse models of allergic asthma
Mosquito salivary sialokinin reduces monocyte activation and chikungunya virus-induced inflammation via neurokinin receptors
Abstract Global warming is expanding mosquito habitats and increasing mosquito-borne diseases. In tropical and sub-tropical regions, chikungunya virus (CHIKV) transmitted by Aedes mosquitoes...
Redox and magma recharge controls on excess sulfur build-up at Mount Samalas, 1257 CE
Large protein-like leader peptides engage differently with RiPP halogenases and lanthionine synthetases
Retraction Note: Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression
Long-range moiré tuning effect via inter-layer drag interaction
The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration
Abstract Changes in the intestinal microbiome and microbiota-derived metabolites predict clinical outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we repo...
A wearable-based aging clock associates with disease and behavior
‘Ghost’ fossils of early coccolithophores point to a Triassic diversification of marine calcifying organisms
Abstract Over geologic time, biocalcification – the process by which marine organisms make calcium carbonate (CaCO3) – has reshaped climates, ocean life, and seawater chemistry. In particula...
Entorhinal grid-like codes for visual space during memory formation
Abstract Eye movements, such as saccades, allow us to gather information about the environment and, in this way, can shape memory. In non-human primates, saccades are associated with...
Signal-strapping as a protein-sequence search method for the discovery of metalloproteins
Abstract Metalloprotein discovery is often made post hoc , in which activity studies following protein isolation reveal a...
Physics-based evolution of transmembrane helices reveals mechanisms of cholesterol attraction
Abstract The existence of linear cholesterol-recognition motifs in transmembrane domains has long been debated. Evolutionary molecular dynamics (Evo-MD) simulations—genetic algorithm...
Tetrahedral DNA dendritic nanostructure-enhanced FISH for high-speed, sensitive spatial transcriptomics
Abstract Understanding where genes are active within tissues is essential to explain how cells build and maintain organs, yet many spatial RNA assays are slow and weak, limiting shor...