Nature Communications
Articles in this Issue
Whole-body CD8+ T-cell PET imaging in patients with large B-cell lymphoma before and during CD19-directed CAR T-cell therapy: a phase 2 study
A de novo missense variant in MIDEAS results in increased deacetylase activity of the MiDAC HDAC complex causing a neurodevelopmental syndrome
Abstract MIDEAS is a scaffold protein that, together with DNTTIP1, mediates assembly of the MiDAC histone deacetylase complex. Mice lacking MiDAC die before birt...
Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection
Ecoresorbable chipless temperature-responsive tag made from biodegradable materials for sustainable IoT
Abstract Temperature monitoring within the cold chain, essential for safety of perishable products, typically employs devices such as battery-powered data loggers and radio-frequency...
Seal milk oligosaccharides rival human milk complexity and exhibit functional dynamics during lactation
Abstract Milk oligosaccharides are crucial for neonatal development and health in mammals. Yet most milk research focuses on humans, or on domesticated mammals t...
Apatinib plus ifosfamide and etoposide versus ifosfamide and etoposide in patients with advanced osteosarcomas (OAIE/PKUPH-sarcoma 11): a randomized phase II study
Latent-TGF-β has a domain swapped architecture
Abstract The multifunctional cytokine TGF-β is a dimeric protein produced within a latent complex (L-TGF-β). Latency is maintained by disulfide linked homodimeric prodomains forming...
Dual-layered mantle lithosphere beneath southeastern Canadian Cordillera
Direct microsecond wide-field single-molecule tracking and super-resolution mapping via CCD vertical shift
Abstract Wide-field single-molecule tracking is often limited by the ~10 ms camera frame time. We introduce SpeedyTrack, which directly enables microsecond wide-...
Sonication-induced J-aggregation in nonhalogenated solvents boosts exciton delocalization for high-efficiency organic solar cells
Global patterns and drivers of nitrogen isotope signal in modern marine sediments
Structural insight into bicarbonate-mediated carboxylation by human vitamin K-dependent carboxylase
Ion-selective interface engineering for durable electrolysis of impure water
Considering distributive justice as a planning principle helps navigate a diversity of future energy infrastructure designs
Abstract The low-carbon energy transition could receive broader societal support if it also delivers a more just distribution of burdens and benefits. However, achieving more just sy...
Solar-driven direct coupling of atmospheric CO2 with ammonia for urea synthesis
Spin transition in magnesiowüstite and ultralow thermal conduction in ultralow velocity zones
Epigenetic and transcriptional programming of murine eosinophils in the esophagus
Current-controlled creations, deletions, and topological transformations of a single magnetic antiskyrmion in nanostructured cells
Single rosette-based generation of uniform cortical assembloids recapitulating cellular interactions between neurons and glial cells
Abstract Despite recent advances, current brain organoid technologies face ongoing challenges in managing heterogeneity and representing the diverse structure and cell types of the h...
Substrate recognition diversity and transport dynamics of ABCC1
Desat1-mediated lipid homeostasis mitigates 20E-induced lipotoxicity in blood-fed mosquitoes
Polymer-constrained excimer enables flexible and self-healable optoelectronic elastomer for mechanical sensor
Abstract The development of high-performance, flexible, and self-healable optoelectronic materials is pivotal for advancing next-generation wearable technologies...
1q gain bypasses the selective barrier against aneuploidy in RPE differentiation via wild-type co-culture rescue
Abstract Human pluripotent stem cells (hPSC) are increasingly used in clinical trials, with retinal pigment epithelium (RPE) being among the most transplanted cell types. However, hP...