Nature Communications

SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation

The TLR7/9 adaptors TASL and TASL2 mediate IRF5-dependent antiviral responses and autoimmunity in mouse

Abstract Endosomal nucleic acid sensing by Toll-like receptors (TLRs) is central to antimicrobial immunity and several autoimmune conditions such as systemic lupus erythematosus (SLE). The i...

Triplet-ground-state nonalternant nanographene with high stability and long spin lifetimes

An essential role for TASL in mouse autoimmune pathogenesis and Toll-like receptor signaling

Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice

Abstract The gut microbiome modulates the anti-seizure effects of the ketogenic diet, but how specific dietary formulations differentially modify the gut microbi...

Force-bearing phagocytic adhesion rings mediate the phagocytosis of surface-bound particles

A dynamic optimization of soil phosphorus status approach could reduce phosphorus fertilizer use by half in China

Mechanical force-induced interlayer sliding in interfacial ferroelectrics

In-situ profiling of glycosylation on single cells with surface plasmon resonance imaging

Gene drive-based population suppression in the malaria vector Anopheles stephensi

Carbon-carbon triple bond cleavage and reconstitution to achieve aryl amidation using nitrous acid esters

Diet-derived urolithin A is produced by a dehydroxylase encoded by human gut Enterocloster species

Author Correction: Layer-by-layer phase transformation in Ti3O5 revealed by machine-learning molecular dynamics simulations

Ion bridging enables high-voltage polyether electrolytes for quasi-solid-state batteries

Direct observation of chiral edge current at zero magnetic field in a magnetic topological insulator

Controllable synthesis of nonlayered high-κ Mn3O4 single-crystal thin films for 2D electronics

Step-necking growth of silicon nanowire channels for high performance field effect transistors

Unravelling genomic drivers of speciation in Musa through genome assemblies of wild banana ancestors

Abstract Hybridization between wild Musa species and subspecies from Southeast Asia is at the origin of cultivated bananas. The genomes of these cultivars are complex mosaics involving nine...

Random resistive memory-based deep extreme point learning machine for unified visual processing

Deep soil contributions to global nitrogen budgets

Development and preclinical testing of a naloxone prodrug depot for extended protection against opioid overdose

When did recombination suppression events occur in bird ZW sex chromosomes?

Chemical tools to define and manipulate interferon-inducible Ubl protease USP18

Abstract Ubiquitin-specific protease 18 (USP18) is a multifunctional cysteine protease primarily responsible for deconjugating the interferon-inducible ubiquitin-like modifier ISG15...

Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal

Myosin-based nucleation of actin filaments contributes to stereocilia development critical for hearing

Abstract Assembly of actin-based stereocilia is critical for cochlear hair cells to detect sound. To tune their mechanosensivity, stereocilia form bundles composed of graded rows of ascendin...