Nature Communications

High H2O2 production in membrane-free electrolyzer via anodic bubble shielding towards robust rural disinfection

Achieving burst Li+ channels via quasi-two-dimensional fluorinated metal-organic framework modulating functionalized interface

Engineering nanozyme immunomodulator with magnetic targeting effect for cascade-enzyodynamic and ultrasound-reinforced metallo-immunotherapy in prostate carcinoma

Polymorphic relaxor phase and defect dipole polarization co-reinforced capacitor energy storage in temperature-monitorable high-entropy ferroelectrics

Cooperation of TRADD- and RIPK1-dependent cell death pathways in maintaining intestinal homeostasis

Thermal biasing for lattice symmetry breaking and topological edge state imaging

Rational design of precatalysts and controlled evolution of catalyst-electrolyte interface for efficient hydrogen production

A randomised controlled non-inferiority trial to compare the efficacy of ‘HPV screen, triage and treat’ with ‘HPV screen and treat’ approach for cervical cancer prevention among women living with HIV

Non-invasive in vivo monitoring of PROTAC-mediated protein degradation using an environment-sensitive reporter

Interpretable single-cell factor decomposition using sciRED

Abstract Single-cell RNA sequencing maps gene expression heterogeneity within a tissue. However, identifying biological signals in this data is challenging due to confounding technic...

Analysis of NS2-dependent effects on influenza PB1 segment extends replication requirements beyond the canonical promoter

Abstract Influenza A virus encodes conserved promoter sequences. Using minimal replication assays—transfections with viral polymerase, nucleoprotein, and a genomic template—these seq...

A rational multi-target combination strategy for synergistic improvement of non-ribosomal peptide production

Intra-somatosensory cortical circuits mediating pain-induced analgesia

WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses

Abstract Signaling from the T cell antigen receptor (TCR) on CD4 +  T cells plays a critical role in adaptive immune resp...

Integrated sensing and communication based on space-time-coding metasurfaces

Longitudinal evaluation of circulating tumor DNA in patients undergoing neoadjuvant therapy for early breast cancer using a tumor-informed assay

Heparan sulfate regulates myofibroblast heterogeneity and function to mediate niche homeostasis during alveolar morphogenesis

Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers

Phosphorylation of FOXN3 by NEK6 promotes pulmonary fibrosis through Smad signaling

The physical roles of different posterior tissues in zebrafish axis elongation

Abstract Shaping embryonic tissues requires spatiotemporal changes in genetic and signaling activity as well as in tissue mechanics. Studies linking specific molecular perturbations to chang...

Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults

Abstract Proteomics offers unique insights into human biology and drug development, but few studies have directly compared the utility of different proteomics platforms. We measured plasma l...

Metallaphotoredox-catalyzed alkynylcarboxylation of alkenes with CO2 and alkynes for expedient access to β-alkynyl acids

Grain boundary diffusion cannot explain the W isotope heterogeneities of the deep mantle

PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection

Magnetic Bloch states at integer flux quanta induced by super-moiré potential in graphene aligned with twisted boron nitride