Nature Communications
Articles in this Issue
Editorial Expression of Concern: ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy
SR-A3 suppresses AKT activation to protect against MAFLD by inhibiting XIAP-mediated PTEN degradation
Dact1 induces Dishevelled oligomerization to facilitate binding partner switch and signalosome formation during convergent extension
Glyphosate is a transformation product of a widely used aminopolyphosphonate complexing agent
Abstract Diethylenetriamine penta(methylenephosphonate) (DTPMP) and related aminopolyphosphonates (APPs) are widely used as chelating agents in household and ind...
PTN activity in quiescent neural stem cells mediates Shank3 overexpression-induced manic behavior
Sub-minute synthesis and modulation of β/λ-MxTi3-xO5 ceramics towards accessible heat storage
Psychological booster shots targeting memory increase long-term resistance against misinformation
Abstract An increasing number of real-world interventions aim to preemptively protect or inoculate people against misinformation. Inoculation research has demons...
Atlas of imprinted and allele-specific DNA methylation in the human body
Discovery of the widespread site-specific single-stranded nuclease family Ssn
Accelerating discovery of bioactive ligands with pharmacophore-informed generative models
Abstract Deep generative models have advanced drug discovery but often generate compounds with limited structural novelty, providing constrained inspiration for medicinal chemists. To addres...
Gradient all-nanostructured aerogel fibers for enhanced thermal insulation and mechanical properties
In vivo prime editing rescues photoreceptor degeneration in nonsense mutant retinitis pigmentosa
Topologically reconfigurable room-temperature polariton condensates from bound states in the continuum in organic metasurfaces
Mitochondria are positioned at dendritic branch induction sites, a process requiring rhotekin2 and syndapin I
Abstract Proper neuronal development, function and survival critically rely on mitochondrial functions. Yet, how developing neurons ensure spatiotemporal distribution of mitochondria during...
Activation of endogenous full-length utrophin by MyoAAV-UA as a therapeutic approach for Duchenne muscular dystrophy
Systematic analysis of cotranscriptional RNA folding using transcription elongation complex display
Berberine-inspired ionizable lipid for self-structure stabilization and brain targeting delivery of nucleic acid therapeutics
How to stop being surprised by unprecedented weather
Abstract We see unprecedented weather causing widespread impacts across the world. In this perspective, we provide an overview of methods that help anticipate unprecedented weather hazards t...
Tebentafusp, a T cell engager, promotes macrophage reprogramming and in combination with IL-2 overcomes macrophage immunosuppression in cancer
Enzyme-activating B-cell receptors boost antigen presentation to pathogenic T cells in gluten-sensitive autoimmunity
Abstract Autoantibodies against the enzyme transglutaminase 3 (TG3) are characteristic to the gluten-sensitive skin disorder dermatitis herpetiformis (DH), which is an extraintestinal manife...
Edge-guided inverse design of digital metamaterial-based mode multiplexers for high-capacity multi-dimensional optical interconnect
Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African men
Abstract Prostate cancer (PCa) is highly heritable, with men of African ancestry at greatest risk and associated lethality. Lack of representation in genomic dat...
Electrochemical cobalt-catalyzed semi-deuteration of alkynes to access deuterated Z-alkenes
Abstract Deuterium labeling has found extensive applications across various research fields, including organic synthesis, drug design, and molecular imaging. Electrocatalytic semi-hydrogenat...