Nature Communications
Articles in this Issue
In vivo armed macrophages curb liver metastasis through tumor-reactive T-cell rejuvenation
Abstract Despite recent progress in cancer treatment, liver metastases persist as an unmet clinical need. Here, we show that arming liver and tumor-associated macrophages in vivo to co-expre...
Trans-ancestry GWAS identifies 59 loci and improves risk prediction and fine-mapping for kidney stone disease
Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography
Abstract Microbial rhodopsins form a diverse family of light-sensitive seven-transmembrane helix retinal proteins that function as active proton or ion pumps, passive light-gated ion channel...
Brain-wide microstrokes affect the stability of memory circuits in the hippocampus
Abstract Cognitive deficits affect over 70% of stroke survivors, yet the mechanisms by which multiple small ischemic events contribute to cognitive decline remain poorly understood....
Balance between bile acid conjugation and hydrolysis activity can alter outcomes of gut inflammation
Author Correction: Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations
Structural basis of cytokinin transport by the Arabidopsis AZG2
Structural Insights into Bortezomib-Induced Activation of the Caseinolytic Chaperone-Protease System in Mycobacterium tuberculosis
Abstract The caseinolytic protease (Clp) system has recently emerged as a promising anti-tuberculosis target. The anti-cancer drug bortezomib exhibits potent anti-mycobacterial activity and...
Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise
Patterns and drivers of diatom diversity and abundance in the global ocean
Abstract Diatoms constitute one of the most diverse and ecologically important phytoplankton groups, yet their large-scale diversity patterns and drivers of abun...
Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records
An innovative approach using CRISPR-ribonucleoprotein packaged in virus-like particles to generate genetically engineered mouse models
Abstract Genetically engineered mouse models (GEMMs) are crucial for investigating disease mechanisms, developing therapeutic strategies, and advancing fundamental biological research. While...
Dynamic categorization rules alter representations in human visual cortex
Synthesis of aromatic amides from lignin and its derivatives
Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits
Detection of single-mode thermal microwave photons using an underdamped Josephson junction
Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex
Abstract Cytokines of the TGF-β superfamily control essential cell fate decisions via receptor regulated SMAD (R-SMAD) transcription factors. Ligand-induced R-SMAD phosphorylation in...
Tensor-FLAMINGO unravels the complexity of single-cell spatial architectures of genomes at high-resolution
Natural killer cells’ functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes
Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele
Abstract Obesity is a major public health crisis associated with high mortality rates. Previous genome-wide association studies (GWAS) investigating body mass in...
A comprehensive suite for extracting neuron signals across multiple sessions in one-photon calcium imaging
Abstract We developed CaliAli, a comprehensive suite designed to extract neuronal signals from one-photon calcium imaging data collected across multiple sessions in free-moving conditions in...
Insights into lattice oxygen and strains of oxide-derived copper for ammonia electrosynthesis from nitrate
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
Targeting vascular adhesion protein-1 and myeloperoxidase with a dual inhibitor SNT-8370 in preclinical models of inflammatory disease
Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice
Abstract Clinical and genetic research links altered cholesterol metabolism with ALS development and progression, yet pinpointing specific pathomechanisms remain challenging. We investigated...