Nature Communications
Articles in this Issue
Multicenter target trial emulation to evaluate corticosteroids for sepsis stratified by predicted organ dysfunction trajectory
Diminished biophysical cooling benefits of global forestation under rising atmospheric CO2
Low temperature near-field fingerprint spectroscopy of 2D electron systems in oxide heterostructures and beyond
Abstract Confined electron systems, such as 2D electron gases (2DEGs), 2D materials, or topological insulators, show great technological promise but their susceptibility to defects often res...
Neoadjuvant PARP inhibitor scheduling in BRCA1 and BRCA2 related breast cancer: PARTNER, a randomized phase II/III trial
Abstract Poly (ADP-ribose) polymerase inhibitors (PARPi) exploit DNA repair deficiency in germline BRCA1 and BRCA2 pathogenic variant (gBRCAm) cancers. Haematological toxicity limits chemoth...
Vitamin D supplementation ameliorates ductular reaction, liver inflammation and fibrosis in mice by upregulating TXNIP in ductular cells
Combining spatial transcriptomics with tissue morphology
Sex differences in the genetic regulation of the human plasma proteome
Abstract Mechanisms underlying sex differences in the development and prognosis of many diseases remain largely elusive. Here, we systematically investigated sex differences in the genetic r...
A clinically applicable AI system for detection and diagnosis of bone metastases using CT scans
GDF8 and activin A blockade protects against GLP-1–induced muscle loss while enhancing fat loss in obese male mice and non-human primates
Desymmetric esterification catalysed by bifunctional chiral N-heterocyclic carbenes provides access to inherently chiral calix[4]arenes
Tad pili with adaptable tips mediate contact-dependent killing during bacterial predation
Abstract The predatory bacterium, Myxococcus xanthus, kills its prey by contact, using a putative Tight Adherence pilus, known as the Kil system, along with a protein complex resembling the...
Electroreduction of diluted CO2 to multicarbon products with high carbon utilization at 800 mA cm–2 in strongly acidic media
TRIM23 mediates cGAS-induced autophagy in anti-HSV defense
Multicationic interactions mitigating lattice strain in sodium layered cathodes
Acute regulation of murine adipose tissue lipolysis and insulin resistance by the TGFβ superfamily protein GDF3
Abstract TGFβ superfamily proteins can affect cellular differentiation, thermogenesis, and fibrosis in mammalian adipose tissue. Here we describe a role for Growth Differentiation Factor 3 (...
DiffInvex identifies evolutionary shifts in driver gene repertoires during tumorigenesis and chemotherapy
Nivolumab plus low-dose ipilimumab in hypermutated HER2-negative metastatic breast cancer: a phase II trial (NIMBUS)
The classical-to-quantum crossover in the strain-induced ferroelectric transition in SrTiO3 membranes
Single-molecule visualization of ATP-induced dynamics of the subunit composition of an ECF transporter complex under turnover conditions
Abstract Energy-Coupling Factor (ECF) transporters are ATP-binding cassette (ABC) transporters essential for uptake of vitamins and cofactors in prokaryotes. They have been linked to pathoge...
Rhythmic radial oxygen loss enhances soil phosphorus bioavailability
GDF8 and activin A are the key negative regulators of muscle mass in postmenopausal females: a randomized phase I trial
Exciton-phonon coupling and phonon-assisted exciton relaxation dynamics in In1-xGaxP quantum dots
Altermagnetism in the layered intercalated transition metal dichalcogenide CoNb4Se8
Token-Mol 1.0: tokenized drug design with large language models
Thermal spectrometer for superconducting circuits
Abstract Superconducting circuits provide a versatile and controllable platform for studies of fundamental quantum phenomena as well as for quantum technology applications. A conventional te...